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Dietary microbes and functional dyspepsia: modulating the gut microecology for therapeutic benefit
Published 2025-08-01“…Dietary microorganisms, capable of modulating gut microecology and thereby influencing gastrointestinal function, are being explored as a promising therapeutic strategy against FD. …”
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Massively parallel interrogation of human functional variants modulating cancer immunosurveillance
Published 2025-03-01“…Our findings provide an unprecedented resource of functional residues that regulate cancer immunosurveillance, offering valuable guidance for clinical diagnosis, ICB therapy, and the development of innovative drugs for cancer treatment.…”
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Neuroticism modulates functional connectivity of the midcingulate cortex during emotional conflict
Published 2025-04-01“…Generalized psychophysiological interaction (gPPI) analyses revealed that individuals with high NT were characterized by decreased functional connectivity between the anterior midcingulate cortex (aMCC) and both the left dorsolateral prefrontal cortex (dlPFC) and the left amygdala. …”
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Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity
Published 2025-01-01“…For example, neutrophils regulate ongoing inflammation by modulating macrophage function through efferocytosis, T cell responses by antigen presentation and the release of cytokines. …”
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The effect of modulators on lung function following inpatient treatment for CF exacerbations
Published 2025-08-01Subjects: “…lung function…”
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Light-dependent modulation of protein localization and function in living bacteria cells
Published 2024-12-01“…Abstract Most bacteria lack membrane-enclosed organelles and rely on macromolecular scaffolds at different subcellular locations to recruit proteins for specific functions. Here, we demonstrate that the optogenetic CRY2-CIB1 system from Arabidopsis thaliana can be used to rapidly direct proteins to different subcellular locations with varying efficiencies in live Escherichia coli cells, including the nucleoid, the cell pole, the membrane, and the midcell division plane. …”
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Multi-functional integrated technical support platform of aircraft maintenance
Published 2020-12-01Subjects: Get full text
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Refinement of the Co-Content function, through an integration of a polynomial fit of $$I-{I}_{sc}$$ I - I sc . Part 2 application to experimental current–voltage curves
Published 2025-01-01Subjects: “…Co-Content function…”
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A deep learning framework for predicting disease-gene associations with functional modules and graph augmentation
Published 2024-06-01“…Experimental results underscore the superiority of ModulePred, showcasing the effectiveness of incorporating functional modules and graph augmentation in predicting disease-gene associations. …”
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Retracted: Function Matching of Terminal Modules of Intelligent Furniture for Elderly Based on Wireless Sensor Network
Published 2020-01-01“…Therefore, it is very necessary to actively carry out research on the function matching of smart adaptable furniture terminal modules based on wireless sensor networks. …”
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Cholesterol Oxidase Binds TLR2 and Modulates Functional Responses of Human Macrophages
Published 2014-01-01Get full text
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Speaker differences in volitional voice modulation reflected in empathy and functional activation patterns
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Nitrogen-functionalized modulation of iron nanoparticles promotes selective hydrogenation of carbon dioxide
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Light-driven modulation of proximity-enhanced functionalities in hybrid nano-scale systems
Published 2025-08-01“…Abstract Advancing quantum information and communication technology requires smaller and faster components with actively controllable functionalities. This work presents an all-optical strategy for dynamically modulating magnetic properties via proximity effects controlled by light. …”
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Functional connectivity and GABAergic signaling modulate the enhancement effect of neurostimulation on mathematical learning.
Published 2025-07-01“…Our multimodal approach elucidates the causal role of the dlPFC and frontoparietal network in a critical academic learning skill, shedding light on the interplay between functional connectivity and GABAergic modulation in the efficacy of brain-based interventions to augment learning outcomes, particularly benefiting individuals who would learn less optimally based on their neurobiological profile.…”
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Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62
Published 2013-01-01“…However, in addition to their pathogenic roles in allergic and autoimmune diseases, mast cells are important in fighting infection, wound healing, and resolving inflammation, reflecting that mast cells exhibit a phenotypic and functional plasticity. We have therefore characterised the differential functional responses to antigen (via FcεRI) and LPS and their modulation by ES-62 of the mature peritoneal-derived mast cells (PDMC; serosal) and those of the connective tissue-like mast cells (CTMC) and the mucosal-like mast cells derived from bone marrow progenitors (BMMC) as a first step to produce disease tissue-targeted therapeutics based on ES-62 action. …”
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Modulation of innate antigen-presenting cell function by pre-patent schistosome infection.
Published 2013-01-01“…Finally, we show that loss of T cell stimulatory capacity may in part be due to suppression of IL-12 expression during pre-patent schistosome infection. Modulation of CD4(+) T cell and APC function may be an aspect of host immune exploitation by schistosomes, as both cell types influence parasite development during pre-patent schistosome infection.…”
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