CONTENT AND STRUCTURE OF THE AUTHOR’S DISCIPLINE “TECHNIQUES OF PEDAGOGICAL MANAGEMENT” by Marianna V. Shvardak

“…The structure of the discipline is given: content modules, and topics. The main methods of training and control of applicants’ knowledge are also identified. …”
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Approach to knowledge management and the development of a multi-agent knowledge representation and processing system by E. I. Zaytsev, E. V. Nurmatova

“…The aim of the present work is to identify models and methods, as well as software modules and tools, for use in developing a highly efficient MKRPS.Methods. …”
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Engaging with clean power: integrated, hands-on lessons on photocatalytic hydrogen production for high school students by Han Fu, Zhenhua Pan, Jill Wenderott

“…Module 3 takes learning outdoors, where students examine the effects of natural sunlight and environmental factors on photocatalytic efficiency, thereby gaining practical understanding of how photocatalysis functions in real-world conditions. …”
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DynamicVLN: Incorporating Dynamics into Vision-and-Language Navigation Scenarios by Yanjun Sun, Yue Qiu, Yoshimitsu Aoki

“…Our approach establishes a benchmark for developing agents capable of functioning in real-world, dynamic environments and extending beyond the limitations of static VLN tasks to more practical and versatile applications.…”
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Design and Implementation of an Integrated Underwater Wireless Optical Communication and Ranging System by WANG Jiale, ZHENG Kaiwen, LIAN Jie

“…【Conclusion】These findings indicate that the proposed OICAR system can realize efficient underwater communication and precise ranging functions in real time.…”
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UAV-DETR: An Enhanced RT-DETR Architecture for Efficient Small Object Detection in UAV Imagery by Yu Zhou, Yan Wei

“…Architecturally extending the RT-DETR framework, UAV-DETR incorporates three novel modules: the Channel-Aware Sensing Module (CAS), the Scale-Optimized Enhancement Pyramid Module (SOEP), and the newly designed Context-Spatial Alignment Module (CSAM), which integrates the functionalities of contextual and spatial calibration. …”
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Autonomous Streaming Space Objects Detection Based on a Remote Optical System by V. S. Baranova, V. A. Saetchnikov, A. A. Spiridonov

“…But the speed of the computing architecture and the functions of small optical systems are rapidly developing thus contribute to the use of a dynamic video stream for detecting and initializing space objects. …”
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Helmet Detection Device for Motorcycles for Safety Riding Porpuses by Dahlan Abdullah, Badriana Badriana, Misbahul Jannah, Dewi Rahayu, Bambang Setiaji, Cut Ita Erliana

“…Our study demonstrates that the designed system functions effectively. It operates only when the rider is wearing a helmet, enabling the motorcycle to start by activating a relay that connects power to the motorcycle socket. …”
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Data-driven prediction and design of bZIP coiled-coil interactions. by Vladimir Potapov, Jenifer B Kaplan, Amy E Keating

“…Our model, which expresses interaction energies as a sum of interpretable residue-pair and triplet terms, achieves a correlation with experimental binding free energies of R = 0.68 and significantly out-performs other scoring functions. To use our model in protein design applications, we devised a strategy in which synthetic peptides are built by assembling 7-residue native-protein heptad modules into new combinations. …”
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Deciphering the structural and dynamic effects of SHP2-E76 mutations: mechanistic insights into oncogenic activation by Humaira Rafiq, Lu Han, Ashfaq Ur Rehman, Pei He, Ali Saber Abdelhameed, Eman S. G. Hassan, Hongxia Fu, Abdul Wadood, Junjian Hu

“…These mutations disrupt the closed conformation, which normally keeps SHP2 in an inactive, auto-inhibited state, thereby enhancing phosphatase activity and activating SHP2, leading to a gain-of-function effect. However, the structural and functional implications of these disease-related mutants are not well elucidated. …”
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MEP-YOLOv5s: Small-Target Detection Model for Unmanned Aerial Vehicle-Captured Images by Shengbang Zhou, Song Zhang, Chuanqi Li, Shutian Liu, Dong Chen

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CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) by Jun-Lin Lv, Jun-Lin Lv, Ru Ma, Ru Ma, Yu-Shan Ren, Qing-Yue Liang, He-Meng Zhang, Gui-Cheng Dong, Jie Li

“…Furthermore, certain circRNAs function as effective microRNA sponges, thereby inhibiting oncogenic pathways in OSCC. …”
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Experience with nusinersen as a pathogenetic therapy in adult patients with spinal muscular atrophy 5q in the Republic of Bashkortostan by S. V. Umutbaev, L. Sh. Murzabaeva, M. A. Kutlubaev, A. V. Shishigin, T. N. Sharipov, E. V. Sayfullina, R. V. Мagzhanov

“…We examined eight patients receiving pathogenetic therapy with nusinersen (SMA type 2 – 34.5 %, SMA type 3 – 65.5 %). The Hammersmith Functional Motor Scale Expanded (HFMSE) and the Revised Upper Limb Module (RULM) were used for evaluating the effectiveness of therapy.Results. …”
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Feeding Regulates the Expression of Pancreatic Genes in Gastric Mucosa by Maria Rita De Giorgio, Mayumi Yoshioka, Jonny St-Amand

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Synthesis and Characterisation of Multivariate Metal–Organic Frameworks for Controlled Doxorubicin Absorption and Release by Ahmed Ahmed, Andrey Bezrukov, Debobroto Sensharma, Ciaran O’Malley, Michael J. Zaworotko, Davide Tiana, Constantina Papatriantafyllopoulou

“…Furthermore, the absorption and release rates of the drug are modulated by the ratio of functional groups, providing a promising approach for controlling drug delivery properties in MOFs.…”
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Standard mouse diets lead to differences in severity in infectious and non-infectious colitis by Joshua E. Denny, Julia N. Flores, Nontokozo V. Mdluli, Michael C. Abt

“…Factors like diet that shape microbiota composition and function may modulate C. difficile colitis. Here, we report that mice fed two distinct standard mouse chows (LabDiet 5010 and LabDiet 5053) exhibited significantly different susceptibility to severe C. difficile infection. …”
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OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis by Chunlei He, Qiang Wu, Zhaogan Zeng, Yadong Yang, Huabin He, Meiyu Hu, Sheng Liu

“…However, its specific functions in osteoarthritis (OA) progression remain undetermined.Objective This study focused on the target proteins of OGT-induced O-GlcNAcylation in OA and the specific functional mechanism.Methods The levels of total O-GlcNAc and OGT were measured in both in vitro and in vivo OA models using western blot. …”
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Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

“…Emerging strategies, such as selective NOX inhibitors, antioxidant therapies, and agents modulating signaling transduction, offer promising avenues for mitigating oxidative injury and improving cardiac function. …”
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Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells by Inge Varik, Katariina Johanna Saretok, Kristine Rosenberg, Ileana Quintero, Maija Puhka, Nataliia Volkova, Aleksander Trošin, Paolo Guazzi, Agne Velthut‐Meikas

“…This study highlights the molecular and functional distinctions between small (SEV) and large (LEV) FF EV subpopulations, revealing their specialised regulatory roles in granulosa cell (GC) biology and their consequential impact on ovarian function. …”
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Exploring the capabilities of repetitive transcranial magnetic stimulation in major depressive disorder: Dynamic causal modeling of the neural network by Akira Kita, Takuya Ishida, Natsuko Kita, Michiyo Tabata, Atsushi Tamaki, Shinya Uenishi, Kasumi Yasuda, Shun Takahashi, Hiroki Matsuura, Shinichi Yamada, Sohei Kimoto

“…These aberrant connections may support the neural mechanisms of MDD and indicate rTMS may modulate these areas, potentially improving the disrupted function in MDD. …”
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