Extracellular Signaling Molecules from Adipose-Derived Stem Cells and Ovarian Cancer Cells Induce a Hybrid Epithelial-Mesenchymal Phenotype in a Bidirectional Interaction by Vinícius Augusto Simão, Juliana Ferreira Floriano, Roberta Carvalho Cesário, Karolina da Silva Tonon, Larissa Ragozo Cardoso de Oliveira, Flávia Karina Delella, Fausto Almeida, Lucilene Delazari dos Santos, Fábio Rodrigues Ferreira Seiva, Débora Aparecida Pires de Campos Zuccari, João Tadeu Ribeiro-Paes, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa

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Structural flexible magnetic films for biometric encryption and tactile interaction in wearable devices by Runyi Deng, Xuejiao Li, Shiqian Cai, Yang Luo, Yangqianhui Zhang, Biyan Wang, Wenbiao Zhou, Huikai Xie, Guozhen Shen, Guofang Gong, Huayong Yang, Xiaoyi Wang, Dong Han

“…Here, we report using magnetization structures and combinations of magnetic materials to achieve two types of functions: 6 n × n invisible secure encryption is achieved through a n × n dipole magnetic array, and multipole magnets are used to achieve decoupling of pressure at various positions and sliding in different directions. …”
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Different effects of prolonged β-adrenergic stimulation on heart and cerebral artery by Eunji Shin, Kyung Soo Ko, Byoung Doo Rhee, Jin Han, Nari Kim

“…Although catecholamines have identical sites of action in the heart and cerebral artery, the structural and functional modifications differentially activate intracellular signaling cascades. βAR-stimulation can increase oxidative stress in the heart and cerebral artery, but has also been shown to induce different cytoskeletal and functional modifications by modulating various components of the βAR signal transduction pathways. …”
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Co-design methodology for rapid prototyping of modular robots in care settings by Alexandre Colle, Alexandre Colle, Alexandre Colle, Alexandre Colle, Alexandre Colle, Karen Donaldson, Karen Donaldson, Mauro Dragone, Mauro Dragone, Mauro Dragone

“…The proposed approach was applied in the development of Robobrico, a modular robot created collaboratively with care home users.ResultsOutcomes from this study demonstrate that this structured process effectively aligns robot functionality with user expectations, enhances adaptability, and facilitates practical integration of modular robotic platforms in real-world care environments.DiscussionThis paper details the proposed methodology, the tools developed to support it, and key insights derived from its implementation.…”
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A cerium nanocluster for effective alleviation of inflammatory bowel disease by scavenging RONS and regulating gut microbiome by Dan Yang, Rong Wang, Lei Zhao, Ye Xu, Yufeng Zhu, Jingyan Zhang, Zhiguo Zhou, Yun Sun, Shiping Yang, Hong Yang, Wu Wang

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Effect of Diet on HDL in Obesity by Tiziana Bacchetti, Camilla Morresi, Oriana Simonetti, Gianna Ferretti

“…There is increasing evidence that white adipose tissue (WAT) participates in several metabolic activities and modulates HDL-C levels and function. In obese subjects, the changes in morphology and function of adipose tissue lead to impaired regulatory function and are associated with a state of low-grade chronic inflammation, with increased release of pro-inflammatory adipokines and cytokines. …”
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Involvement of the tryptophan-kynurenine pathway in the pathogenesis of autoimmune diseases by A-Yuan Chen, Ying-Jie Zhao, Yue-Ye Wang, Wei Wei, Wei Hu, Yan Chang

“…The kynurenine pathway (KP), a major metabolic pathway for L-tryptophan (Trp) in mammals, plays a multifaceted role in various physiological processes, including neural activity, immune system regulation, and the maintenance of intestinal homeostasis. The functional connection between the KP and immune system is supported by robust evidence, including disease-associated alterations in KP metabolite concentrations and enzyme activities that correlate with immune function changes. …”
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Lactate-mediated metabolic reprogramming of tumor-associated macrophages: implications for tumor progression and therapeutic potential by Xiaohan Jin, Xiaohan Jin, Xiaohan Jin, Ni Zhang, Tinghao Yan, Jingyang Wei, Lingli Hao, Changgang Sun, Haibo Zhao, Shulong Jiang, Shulong Jiang, Shulong Jiang

“…Among these adaptations, lactate, a key metabolic byproduct of aerobic glycolysis, accumulates in the TME and plays a pivotal role in regulating cellular metabolism and immune cell function. Tumor-associated macrophages (TAMs), known for their remarkable functional plasticity, serve as critical regulators of the immune microenvironment and tumor progression. …”
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Ferroelectric‐Assisted Ion Dynamics for Prolonged Tactile Cognizance in a Biomimetic Memory‐in‐Sensor System by Ritamay Bhunia, Joo Sung Kim, Hayoung Oh, Dong Jun Kim, Seokyeong Lee, Cheolmin Park, Do Hwan Kim

“…However, poor tactile memory and the complexity of integrating diverse modules for tactile sensing and neuromorphic functionalities pose a formidable challenge. …”
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Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of G... by Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo

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Effect of soy isoflavones on intraepithelial lymphocytes, goblet cells and long leptin receptor in intestinal of rats by TANG Xiuying, CHEN Zhengli, LUO Qihui, ZHANG Xiaolong

“…Some studies have shown that it could modulate immune function and prevention of chronic diseases, but until now it remains controversial. …”
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Small molecule disruption of RARα/NCoR1 interaction inhibits chaperone-mediated autophagy in cancer by Mericka McCabe, Rajanya Bhattacharyya, Rebecca Sereda, Olaya Santiago-Fernández, Rabia R Khawaja, Antonio Diaz, Kristen Lindenau, Deniz Gulfem Ozturk, Thomas P Garner, Simone Sidoli, Ana Maria Cuervo, Evripidis Gavathiotis

“…The lack of a specific target for CMA inhibition has limited CMA blockage to genetic manipulations or global lysosomal function inhibition. Here, using genetic modulation, transcriptional analysis, and functional studies, we demonstrate a regulatory role for the interaction of the retinoic acid receptor alpha (RARα) and its corepressor, the nuclear receptor corepressor 1 (NCoR1), on CMA in non-small cell lung cancer (NSCLC). …”
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<i>Pseudorabies Virus</i> IE180 Inhibits Virus Replication by Activating the Type I Interferon Pathway by Feiyang Zheng, Jingjing Song, Xuan Chen, Dongyue Xing, Rulan Bai, Changyong Cheng, Jin Yuan, Rui Zhang

“…Notably, IE180 failed to suppress PRV or H1N1 replication in Vero cells, which lack functional IFN-I signaling, confirming the dependence of its antiviral function on the IFN-I pathway. …”
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Research progress on NAT10-mediated acetylation in normal development and disease by Da Qin, Qing Liu, Xiaochao Ma, Rui Wang, Tianyu Lu, Yue Yang, Ze Tang, Yanbo Zhu

“…It regulates RNA stability, translation, and post-transcriptional processes. Meanwhile, NAT10 functions as a dual-function enzyme exhibiting both protein acetyltransferase and RNA acetylase activities. …”
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Design and implementation of civil aircraft test database for multi-discipline integration by LI Xinyang, FENG Yunwen, LI Jian, LU Cheng, XIE Yajun, YANG Li

“…The logical relationships between the storage content of various test modules are clarified，then the flight module serving as an example is taken for detailed database module design. …”
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Role and mechanism of heparin in cardiovascular system by Xianqiang Yu

“…Heparin, a widely used anticoagulant, plays a crucial role in cardiovascular function by exerting multifaceted effects. This review explores heparin’s impact on the cardiovascular system, emphasizing its anticoagulant properties, modulation of endothelial function, anti-inflammatory effects, platelet inhibition, and influence on vascular remodeling. …”
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Analysis and validation of characteristic genes in RNA sequencing datasets from heart failure patients based on multiple algorithms by Yuxuan Li, Ying Bai, Wujiao Wang, Zhaotian Ma, Peng Li, Dong Li, Sinai Li, Jialin Jin, Jialin Jin, Qian Lin

“…Functional enrichment analyses (GO, KEGG, GSEA) revealed associated functional alterations. …”
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Development of intelligent traction machine for tensioning and paying off construction of transmission lines by Xiaobin Li, Shuo Wang, Feng Wang, Riping Zheng, Zixin Li, Hongbing Wen

“…The data transmission module transmits monitoring data to the construction site terminal equipment and remote command center through LoRa wireless transmission technology, displays monitoring data on the terminal equipment, and realizes warning and control functions. …”
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Her IMPROVE TEACHERS' INNOVATIVE DIGITAL SKILLS ACROSS EUROPE by Ana Afonso, Isabel Cristina Carvalho, José Bidarra, Lina Morgado, Antonieta Rocha

“…This data informed a pilot program with 80 Vocational Education and Training and Higher Education teachers to test the functionality of the digital Toolkit, the e-learning platform, design, quality, and impact of the content. …”
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Double-End Location Technology of Partial Discharge in Cables Based on Frequency-Domain Reflectometry by Wang Miao, Hongjing Liu, Ci Song, Hongda Li, Nan He, Jingzhu Teng, Baoqin Cao, Ruonan Bai, Xianglong Li, Haibao Mu

“…The frequency band modulation technique determines the effective frequency band range of the acquired cable transfer function through the frequency band range of the partial discharge signals measured at both ends, which ensures the reliability of the transfer function. …”
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