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5621
Fibroblast heterogeneity and its role in generating protective immunity in the secondary lymphoid organs
Published 2025-04-01“…The role of trans-differentiated effector fibroblast phenotypes that modulate the expression and function of various innate immune components (PRRs, cytokines, chemokines, and complement) in maintaining homeostasis has also been discussed.…”
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5622
Herpes simplex virus type 1 impairs mucosal-associated invariant T cells
Published 2025-05-01“…It is unknown whether HSV-1 can infect MAIT cells and modulate their functions. Here, we show that HSV-1 can infect primary human MAIT cells, including CD4±/CD8± and CD56± MAIT cell subpopulations. …”
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5623
P86 | THE EFFECTS OF NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITION ON THE EXPRESSION OF BRAIN DERIVED NEUROTROPHIC FACTOR IN THE OLFACTORY BULB ORGANOTYPIC SLICE CULTURES
Published 2025-08-01“…Demonstration of the role of BDNF signaling in olfactory bulb neurogenesis provided the first link between disruptions in neurotrophin signaling and olfactory behavioural performance. Impaired olfactory function appears to be one of the earliest detectable functional alterations in Alzheimer disease1,2. …”
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5624
Acute and chronic gene expression activation following medial forebrain bundle DBS and selective dopamine pathway stimulation
Published 2025-02-01“…In addition, clinical implication of the data is that unilateral stimulation had bilateral consequences on the gene expression, although the physiological and functional sequelae of this are yet unknown.…”
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5625
Reliability Analysis of Hybrid Laser INS Under Multi-Mode Failure Conditions
Published 2025-03-01“…A reliability analysis model is established, considering both functional and structural strength failures. To address uncertainties from manufacturing, technical conditions, material selection, and assembly errors, a global sensitivity analysis based on Bayesian inference evaluates parameter contributions to functional failure probability, using a sample size of N1 = 5 × 10<sup>5</sup>. …”
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5626
pyRoCS: A Python package to evaluate the resilience of complex systems
Published 2025-02-01“…The metrics used to quantify resilience are sourced from peer-reviewed publications across multiple domains, including information theory, biosciences, and complex systems. Functions within associated domain modules can be combined based on user needs to support the characterization of resilience. …”
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5627
Considerations on civil aircraft design assurance system review
Published 2024-08-01“…By studying the requirements of domestic and foreign airworthiness authorities on design institutions, the core contents and relationship of the DAS three major functions are identified, the main architecture of DAS manual is proposed. 11 modules and 28 elements of DAS review and the corresponding review points are analyzed, and a review idea based on modularity and a review mode based on process intervention are proposed, which can help authorities and industry better carry out the construction and review of DAS.…”
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5628
Trans-active factors controlling the IL-2 gene in adult human T-cell subsets
Published 1992-01-01“…IL-2 secretion in total or subsets of PHA/PMA-stimulated PBMC-derived human T-lymphocytes was monitored and found to be largely due to CD4+CD8− cells. The presence and functional state of transcription factors (TF) was assessed by protein-DNA interaction assays and functional transactivation experiments in the Xenopts oocyte system, modulating IL-2 transcription by injection of proteins. …”
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5629
Integration of IT solutions for resource management in environmentally sustainable agriculture
Published 2024-01-01“…The article also discusses the prospects for further research aimed at improving the accuracy of forecasts, expanding monitoring functions and adapting the system for use in small farms. …”
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5630
Simulation Study of Single-Adsorber Heat Pump Cycle with Heat Recovery Through Stratified Storage in Both Adsorber and Evaporator/Condenser Loops
Published 2024-11-01“…A stratified storage integrated into the primary heat pump loop is employed for heat recovery of the adsorber as well as the EC heat exchanger (functioning both as an evaporator and condenser). A heating system of a stock multifamily residential building in Germany is assumed as the load to be covered by the heat pump. …”
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5631
OsbZIP40 and OsbZIP12 interact with OsMFT1 to repress Ehd1 expression and delay flowering in rice
Published 2025-06-01“…Although many flowering time-related rice genes have been identified and functionally characterized, continuing in-depth research is revealing how transcription of these genes is regulated. …”
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5632
Federated Learning for a Dynamic Edge: A Modular and Resilient Approach
Published 2025-06-01“…The framework is built on decoupled modules handling core FL functionalities, allowing flexibility in integrating various algorithms, communication protocols, and resilience strategies. …”
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5633
Spectrum cognitive intelligent management and control for aviation 6G
Published 2020-03-01“…With the development of the ground-air-space integrated information network,satellite networks and ground mobile networks serve as space and ground fundamental infrastructures,respectively.While various aerial platforms such as drones constitute air mobile networks to connect space and ground infrastructures.As an important form of 6G,aviation 6G will include new types of air-to-air,air-to-ground and air-to-space communication and networking techniques.An important issue for aviation 6G is how to efficiently use spectrum resources.Based on the challenges of aviation 6G and electromagnetic spectrum space,a spectrum cognitive intelligent management and control architecture for aviation 6G was proposed,and the functions were elaborated of the four main modules in the architecture,namely spectrum cloud,spectrum control link,device spectrum software defined and spectrum sensor network.Three key technologies of spectrum cognitive intelligent management and control for aviation 6G were analyzed and discussed,namely intelligent three-dimensional spectrum space digital twins,3D spectrum intelligent decision,and rapid collaborative learning of spectrum mapping.It is expected to provide guidance and suggestions for the subsequent research on aviation 6G and spectrum intelligent management and control.…”
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5634
DESIGN AND CREATION OF A COMMERCIAL WEBSITE – PRACTICAL SOLUTION FOR ELECTRONIC COMMERCE
Published 2024-01-01“…The website features a modularized structure, consisting of administration, authentication, payment, and order launch/cancellation modules. All these components contribute to the optimal functioning of the e-commerce application.…”
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5635
Framework for NFC-Based Intelligent Agents: A Context-Awareness Enabler for Social Internet of Things
Published 2014-02-01“…The resultant social-advertising system shows that this framework can support a wide-range of different functionalities and is indispensable to an NFC-based intelligent agent for social Internet of things.…”
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5636
An Energy Control and Management System forUrban Rail Transit
Published 2021-01-01“…Considering the objective functions and system physical limitations, the energy control and management system optimizes DC output voltage commands of bidirectional converters through heuristic algorithms based on the digital reconstructed traction power system. …”
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5637
Impact of the introduction of the modular written-theoretical examination in the training internship.
Published 2005-12-01“…<strong>Background: </strong>The formative process of teachers has always been a challenge due transformations undergone by educative institution's functions. <strong>Objective</strong>: To compare the results of modular examinations of two editions of the Professional Course. …”
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5638
Network pharmacognosy of Galphimia glauca: Mapping the molecular landscape of a traditional Mexican medicinal plant.
Published 2025-01-01“…Community detection with the Walktrap algorithm further segmented the network into functionally relevant modules linked to cell survival, immune response, and inflammation, reflecting the therapeutic effects historically attributed to G. glauca. …”
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5639
ECONOMIC ANALYSIS OF DEFORESTATION IMPACT ON THE YIELD OF AGRICULTURAL CULTURES IN UKRAINE
Published 2019-01-01“…General concept of the formation and functioning of a forecasting model of scientific and technological development of the region’s agriculture in the digital economy, which is forming in accordance with the well-known Federal program is proposed. …”
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5640
Spectrum cognitive intelligent management and control for aviation 6G
Published 2020-03-01“…With the development of the ground-air-space integrated information network,satellite networks and ground mobile networks serve as space and ground fundamental infrastructures,respectively.While various aerial platforms such as drones constitute air mobile networks to connect space and ground infrastructures.As an important form of 6G,aviation 6G will include new types of air-to-air,air-to-ground and air-to-space communication and networking techniques.An important issue for aviation 6G is how to efficiently use spectrum resources.Based on the challenges of aviation 6G and electromagnetic spectrum space,a spectrum cognitive intelligent management and control architecture for aviation 6G was proposed,and the functions were elaborated of the four main modules in the architecture,namely spectrum cloud,spectrum control link,device spectrum software defined and spectrum sensor network.Three key technologies of spectrum cognitive intelligent management and control for aviation 6G were analyzed and discussed,namely intelligent three-dimensional spectrum space digital twins,3D spectrum intelligent decision,and rapid collaborative learning of spectrum mapping.It is expected to provide guidance and suggestions for the subsequent research on aviation 6G and spectrum intelligent management and control.…”
Get full text
Article