Construction and Testing of Health LifeStyle Evidence (HLSE) by TIAN Chen, WANG Yong, YAN Yilong, LIU Yafei, LU Yao, SUN Mingyao, LIU Jianing, MA Yan, NING Jinling, YE Ziying, CHENG Qianji, LI Ying, HUANG Jiajie, YANG Shuihua, WANG Yiyun, TONG Bo, LU Jiale, GE Long

“…This paper aims to introduce the functional module design of the evidence translation system, the system development process and testing, introduce the interface design and function demonstration, and explain the significance of constructing the HLSE.…”
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Arbuscular Mycorrhizal Fungi: Boosting Crop Resilience to Environmental Stresses by Wenjing Nie, Qinghai He, Hongen Guo, Wenjun Zhang, Lan Ma, Junlin Li, Dan Wen

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Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma by Noelia Moares, Noelia Moares, Pablo Gonzalez-Garcia, Pablo Gonzalez-Garcia, Wenjie Yi-He, Wenjie Yi-He, Juan P. Muñoz-Miranda, Juan P. Muñoz-Miranda, Antonio Gabucio, Antonio Gabucio, Rosa Luna-Espejo, Javier Ocaña-Cuesta, Ricardo Fernandez-Cisnal, Cecilia M. Fernandez-Ponce, Cecilia M. Fernandez-Ponce, Francisco Garcia-Cozar, Francisco Garcia-Cozar

“…This was achieved using a split intein-mediated protein splicing mechanism, which allows specific covalent peptide bonds to form between CAR modules. This strategy maintains an almost seamless CAR structure, preserving its overall integrity and functionality. …”
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Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells by Kerong Liu, Tingting Lv, Lu He, Wei Tang, Yan Zhang, Xiao Xiao, Yating Li, Xiaoai Chang, Shusen Wang, Stephen J. Pandol, Ling Li, Xiao Han, Yunxia Zhu

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RAG suppresses group 2 innate lymphoid cells by Aaron M Ver Heul, Madison Mack, Lydia Zamidar, Masato Tamari, Ting-Lin Yang, Anna M Trier, Do-Hyun Kim, Hannah Janzen-Meza, Steven J Van Dyken, Chyi-Song Hsieh, Jenny M Karo, Joseph C Sun, Brian S Kim

“…Furthermore, we show that RAG modulates ILC2 function in a cell-intrinsic manner independent of the absence or presence of adaptive T and B lymphocytes. …”
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اثير تدريبات الهيبوكسيك باستخدام وسيلة مساعدة على تطوير بعض المتغيرات الوظيفيه لعدائات 800م by زينب قحطان الهاشمي

“… The sports training based on scientific grounds correct factors that increase and improve indicators functional and physical abilities and skills and thus improve sporting achievement, and aerobics are only cramps against opponents certain has been lengthened or shortened at the time of their performance and this depends on the objective of the training and capacity to be training. …”
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OsPP2C49, a Negative Regulatory Factor in the Abscisic Acid Signaling Pathway, Positively Regulates Grain Yield in Rice by Jun Miao, Liubing Bu, Wenchen Tan, Ping Wang, Xiangbo Li, Xianfeng Li, Chuyan Chen, Kunming Zhang, Wenle Shen, Zhiyun Gong, Gulinaer Bahetibieke, Lei Ren, Guohua Liang, Yong Zhou

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Hybrid Electro‐optical Stimulation Improves Ischemic Brain Damage by Augmenting the Glymphatic System by Min Jae Kim, Jiman Youn, Hong Ju Lee, Seo‐Yeon Lee, Tae‐Gyu Kim, Young‐Jin Jung, Yong‐Il Shin, Byung Tae Choi, Joonsoo Jeong, Hwa Kyoung Shin

“…Moreover, hybrid stimulation restores impaired glymphatic system function by modulation of aquaporin‐4 (AQP4) polarization and alleviates the accumulation of proinflammatory cytokines such as IL‐1β. …”
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The autophagy protein ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy by Pooja Popli, Arin K Oestreich, Vineet K Maurya, Marina N Rowen, Yong Zhang, Michael J Holtzman, Ramya Masand, John P Lydon, Shizuo Akira, Kelle Moley, Ramakrishna Kommagani

“…In addition to embryo quality and endometrial function, proper oviduct function is also essential for successful pregnancy establishment. …”
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Advances in Understanding Lipopolysaccharide-Mediated Hepatitis: Mechanisms and Pathological Features by Kazuhiko Nakadate, Hayate Saitoh, Miina Sakaguchi, Fumito Miruno, Naoto Muramatsu, Nozomi Ito, Kanako Tadokoro, Kiyoharu Kawakami

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Advancing inorganic electro-optical materials for 5 G communications: from fundamental mechanisms to future perspectives by Hao Wang, Long Chen, Yao Wu, Suwan Li, Guanlong Zhu, Wei Liao, Yi Zou, Tao Chu, Qiuyun Fu, Wen Dong

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Virtual Coach–Guided Online Acceptance and Commitment Therapy for Chronic Pain: Pilot Feasibility Randomized Controlled Trial by Erin D Reilly, Megan M Kelly, Hannah L Grigorian, Molly E Waring, Karen S Quigley, Timothy P Hogan, Alicia A Heapy, Charles E Drebing, Matias Volonte, Ummul-Kiram Kathawalla, Hannah E Robins, Katarina Bernice, Timothy Bickmore

“…This is often accompanied by negative functional outcomes and higher mortality. Combined with research suggesting medical treatments for chronic pain are often insufficient, there is an urgent need for nonmedical pain self-management programs. …”
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Impact of Cetyl-Containing Ionic Liquids on Metal Halide Perovskite Structure and Photoluminescence by Maegyn A. Grubbs, Roberto Gonzalez-Rodriguez, Sergei V. Dzyuba, Benjamin G. Janesko, Jeffery L. Coffer

“…This optimal enhancement is attributed to a function of accessible surface charges associated with the heterocyclic cation of a given IL and perovskite defect passivation by bromide, the latter elucidated with the help of density functional theory. …”
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Identification of genetically engineered strategies to manipulate nano-platforms presenting immunotherapeutic ligands for alleviating primary ovarian insufficiency progression by Guannan Zhou, Yuanyuan Gu, Menglei Zhang, Jingxin Ding, Guanming Lu, Keqin Hua, Fang Shen

“…Abstract Primary ovarian insufficiency (POI) is a pathological condition characterized by the early loss of functional ovarian follicles, leading to infertility and systemic consequences affecting reproductive, skeletal, cardiovascular, and neurocognitive helath. …”
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Pro-repair macrophages driven by CGRP rescue white matter integrity following intracerebral hemorrhage by Huaping Huang, Yirui Kuang, Yang Chen, Yi Zhang, Jiayin Zhou, Xian Yu, Yonghe Zheng, Lingxin Cai, Wanglu Hu, Liansheng Gao, Haijian WU, Hui Ling, Xiao Dong, Hang Zhou, Xiaobo Yu, Yucong Peng, Gao Chen, Xiaoyu Wang, Wei Yan

“…Abstract Background Intracerebral hemorrhage (ICH) triggers a dynamic immune response involving macrophages, However, the functional heterogeneity of these cells and the mechanisms through which they promote repair remain unclear. …”
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Redox Regulation of cAMP-Dependent Protein Kinase and Its Role in Health and Disease by Ese S. Ekhator, Marco Fazzari, Robert H. Newman

“…This review examines the structural and functional regulation of PKA, with a focus on redox-dependent modifications and their impact on PKA-dependent signaling. …”
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Hematological Changes and Immunomodulation of Neutrophil and Monocyte Populations in Shelter Dogs by Marek Kulka, Iwona Monika Szopa, Maciej Klockiewicz

“…Standard methods of animal health monitoring, such as psychological evaluation or cortisol measurements, do not fully reflect modulation of the immune system. Functional cellular changes may be subtle and observed only at the molecular level. …”
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Discovery of isomiRs in PBMCs of diseased vis-à-vis healthy Indian water buffaloes by Jasdeep Kaur Dhanoa, Jasdeep Singh, Amarjit Singh, Jaspreet Singh Arora, R. S. Sethi, C. S. Mukhopadhyay

“…Gene ontology and pathway analyses of the target genes (Panther classification system) yielded several biological hits. Functional classification of the target genes indicated that these target genes were involved in different systems biology related functions like molecular binding, enzyme modulation, signal modulation, etc. …”
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Spatial dependencies between large-scale brain networks. by Robert Leech, Gregory Scott, Robin Carhart-Harris, Federico Turkheimer, Simon D Taylor-Robinson, David J Sharp

“…Functional neuroimaging reveals both increases (task-positive) and decreases (task-negative) in neural activation with many tasks. …”
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Excitatory-inhibitory homeostasis and bifurcation control in the Wilson-Cowan model of cortical dynamics. by Francisco Páscoa Dos Santos, Paul F M J Verschure

“…Although the primary function of excitatory-inhibitory (E-I) homeostasis is the maintenance of mean firing rates, the conjugation of multiple homeostatic mechanisms is thought to be pivotal to ensuring edge-of-bifurcation dynamics in cortical circuits. …”
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