PRINCIPLES OF CONCEPTUAL APPROACH TO CREATING TOOL SUBSYSTEM FOR MULTIOPERATION MACHINE SMART-PASSPORT by Andrey Kirillovich Tugengold, Andrey Igorevich Izyumov

“…The unit architecture is presented by a set of modules including a data acquisition module, a module for observing changes in the tool state and control, a monitoring module, and others. …”
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Ovalbumin Peptide–Selenium Nanoparticles Alleviate Immune Suppression in Cyclophosphamide-Induced Mice: A Combined Transcriptomic and Proteomic Approach to Reveal the Mechanism by Yingnan Zeng, Qi Yang, Zhiyang Du, Xuanting Liu, Xiaomin Shang, Menglei Xu, Jingbo Liu, Siwen Lyu, Ting Zhang

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Stimulating at the right time to recover network states in a model of the cortico-basal ganglia-thalamic circuit. by Timothy O West, Peter J Magill, Andrew Sharott, Vladimir Litvak, Simon F Farmer, Hayriye Cagnan

“…To do this we setup a neural mass model of population activity within the cortico-basal ganglia-thalamic (CBGT) circuit with parameters that were constrained to yield spectral features comparable to those in experimental Parkinsonism. We modulated the connectivity of two major pathways known to be disrupted in PD and constructed statistical summaries of the spectra and functional connectivity of the resulting spontaneous activity. …”
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Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1. by Frances A Spring, Rebecca E Griffiths, Tosti J Mankelow, Christopher Agnew, Stephen F Parsons, Joel A Chasis, David J Anstee

“…These results strongly suggest that tetraspanins have a functional role in terminal erythropoiesis by modulating interactions of erythroblast α4β1 with both macrophages and extracellular matrix.…”
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Smart tags based on the batteryless backscatter technology:applications and challenges by Ying GUO, Gongpu WANG, Zonghui LI, Ruisi HE, Zhangdui ZHONG

“…Since the radio frequency identification (RFID) technology was put forward,it has been widely used in the transportation,logistics,industry and business due to its convenience and high efficiency.As a carrier for storing recognizable data,the RFID tags play a crucial role in the Internet of things (IoT).More and more functions and modules are embedded in the RFID tags and developed into smart tags in different application fields.Recently,wireless batteryless smart tags have arisen and grown rapidly with the development of the IoT and various emerging backscatter technologies.Wireless batteryless smart tags use the passive backscatter technology to harvest the energy and transmit information through radio frequency signals.Starting from the RFID technology,the history of the RFID and smart tags was introduced briefly,the differences between traditional smart tags and emerging wireless smart tags were compared,the advantages of wireless batteryless smart tags were concluded,several specific applications of it in different fields were listed,and the open challenges were analyzed.…”
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Biofermentation of Wheat Bran by <i>Monascus anka</i> and Production of High Value-Added Dietary Fiber by Xuefeng Wu, Siqi He, Hongyi Xu, Hui Zhang, Jing Cai, Min Zhang, Dongdong Mu, Zhenhong Li, Xingjiang Li, Lanhua Liu

“…In conclusion, <i>M. anka</i> can make the most use of wheat bran and improve the structure and function of dietary fiber, thereby expanding its application potential in functional food additives, gut microbiota modulation, and low-calorie baked goods.…”
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α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology by Yaqiong Zhang, Yaqiong Zhang, Yuanyuan Chen, Chenglin Sun, Fang Li, Yin Shen, Yin Shen

“…In the SI-induced AMD mouse model, ALA significantly preserved retinal structure, maintained visual function, and reduced oxidative stress and iron accumulation. qRT-PCR confirmed that ALA exerted differential effects on the expression of the six genes, demonstrating a context-dependent regulatory mechanism.ConclusionThis study provides multi-level evidence that ALA protects against AMD by modulating ferroptosis-related pathways and restoring retinal structural integrity and functions. …”
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The Association between DRD3 Ser9Gly Polymorphism and Depression Severity in Parkinson’s Disease by Yan Zhi, Yongsheng Yuan, Qianqian Si, Min Wang, Yuting Shen, Lina Wang, Hui Zhang, Kezhong Zhang

“…Our aim was to investigate the potential effect of DRD3 Ser9Gly polymorphism on modulating resting-state brain function and associative clinical manifestations in PD patients. …”
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Tumor-infiltrating lymphocytes in cancer immunotherapy: from chemotactic recruitment to translational modeling by Fatjona Pupuleku Kraja, Vladimir B. Jurisic, Altijana Hromić-Jahjefendić, Nafsika Rossopoulou, Theodora Katsila, Katarina Mirjacic Martinovic, Javier De Las Rivas, Carmen Cristina Diaconu, Árpád Szöőr

“…This review explores the phenotypic and functional diversity of TILs—including CD8+ cytotoxic T cells, CD4+ helper T cells, regulatory T cells, B cells, and natural killer (NK) cells—and their dynamic interactions within the tumor microenvironment (TME). …”
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Measuring. Monitoring. Management. Control by D.L. Ovchinnikov, A.Yu. Tychkov, A.K. Alimuradov, A.V. Ageikin

“…A suitable microcontroller with the ability to expand functionality through built-in modules has been identified, and the type of sensor for determining the position of fingers has been selected. …”

Elastic Properties of the Single-Walled Carbon Nanotubes by O.B. Protsenko, V.V. Yemelyanenko

“…Results of this research can be used for design, analysis and evaluating of functioning and creating new materials based on carbon nanotubes.…”
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Heterosynaptic Regulation of α2A-Adrenoceptors on Glutamate/GABA Release in the Prefrontal Cortex of Rats by Yaru Wei, Yuhan Jiao, Xiaoting He, Xiaodong Tao, Baoming Li, Xuehan Zhang

“…<b>Background/Objectives:</b> Norepinephrine (NE) plays a crucial role in modulating cognitive processes via α2A-adrenoceptors (α2A-ARs) within the prefrontal cortex (PFC), an essential brain region responsible for higher cognitive functions. …”
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Femtosecond laser subtractive/additive-integrated biomimetic manufacturing for visible/infrared encryption and stimuli-responsive infrared decryption by Ruijie Liu, Dongshi Zhang, Zhuguo Li

“…The self-evolution from ‘orderless’ structuring to ‘ordered’ functionalization is validated for the proposed fs laser subtractive/additive-integrated biomimetic manufacturing, specifically from the synthesis of diverse black nanomaterials and the seemingly disordered micro/nano-aggregates to the ordered optical/thermal regulation capacities for a delicate modulation of information encryption and decryption, unveiling a new concept for future exploration and extension.…”
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Comparative analysis of differentially expressed genes in breast cancer across Asian and European populations: insights into molecular pathways and biomarkers by Prabhu Meganathan, Sharvari Sawant, Shreshta Reddy

“…CD36 and LEP could be used in liquid biopsy screening, and their metabolic function supports further investigation into CD36 inhibitors, LEP antagonists, and PPARG modulators. …”
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Effects of USP25 knockout on the gut microbial diversity and composition in mice by Jinqiu Li, Zhonghui Chen, Xingchen Yan, Qizhou Chen, Cirong Chen, Huan Liu, Jianlin Shen

“…Conclusion Our findings elucidate the essential role of USP25 in modulating gut microbiota composition and function, providing insights for future therapeutic strategies targeting gut microbiota in disease contexts. …”
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S100A11 as an immune-related exosomal driver of colorectal cancer progression: a novel diagnostic biomarker by Haibo Wang, Rongchao He, Deng Liu, Jun He, Zhong Shen

“…This study aims to identify exosome-related biomarkers in CRC and elucidate the functional significance of S100A11 in tumor progression and immune regulation.MethodsWe integrated multi-cohort transcriptomic data from TCGA and GEO databases and applied a machine learning triad (LASSO-SVM-Random Forest) to identify robust exosomal biomarkers for CRC. …”
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Assessing the conservation and targets of putative sRNAs in Streptococcus pneumoniae by Matthew C. Eichelman, Michelle M. Meyer

“…Small RNAs (sRNAs) are non-coding RNAs that modulate translation initiation and mRNA degradation by base pairing. …”
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Discovery of novel butyrylcholinesterase inhibitors for treating Alzheimer's disease by Zhipei Sang, Shuheng Huang, Wanying Tan, Yujuan Ban, Keren Wang, Yufan Fan, Hongsong Chen, Qiyao Zhang, Chanchan Liang, Jing Mi, Yunqi Gao, Ya Zhang, Wenmin Liu, Jianta Wang, Wu Dong, Zhenghuai Tan, Lei Tang, Haibin Luo

“…Further, 8e significantly improved cognitive function in APP/PS1 transgenic mice. Proteomics analysis demonstrated that 8e markedly elevated the expression levels of very low-density lipoprotein receptor (VLDLR), offering valuable insights into its potential modulation of the Reelin-mediated signaling pathway. …”
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Transcriptomic Regulatory Mechanisms of Isoflavone Biosynthesis in <i>Trifolium pratense</i> by Kefan Cao, Sijing Wang, Huimin Zhang, Yiming Ma, Qian Wu, Fan Huang, Mingjiu Wang

“…Isoflavones are important secondary metabolites in leguminous plants with significant physiological functions and economic value. However, the genetic variation, transcriptional regulation, and metabolic pathways governing isoflavone biosynthesis in <i>Trifolium pratense</i> remain largely unexplored. …”
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Dual-Valence Copper Nanostructures with Cu⁺/Cu²⁺ Interfaces for High-Sensitivity Glucose Electrochemical Sensing by Zhipeng Yu, Pengxu Yan, Yilei Sheng, Chengwei Zhang, Zhun Qiao, Qikui Fan, Chuncai Kong, Zhimao Yang

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