Repetitive peripheral magnetic stimulation alone or in combination with repetitive transcranial magnetic stimulation in poststroke rehabilitation: a systematic review and meta-anal... by Yong Wang, Kenneth N. K. Fong, Youxin Sui, Zhongfei Bai, Jack Jiaqi Zhang

“…Abstract Objective This study aimed to comprehensively review the effects of repetitive peripheral magnetic stimulation (rPMS) alone or in combination with repetitive transcranial magnetic stimulation (rTMS) on improving upper limb motor functions and activities of daily living (ADL) in patients with stroke, and to explore possible efficacy-related modulators. …”
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Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty... by Brianna J Stubbs, Gabriela Alvarez Azañedo, Sawyer Peralta, Stephanie Roa Diaz, Wyatt Gray, Laura Alexander, Wendie Silverman-Martin, Thelma Y Garcia, Traci M Blonquist, Vaibhav Upadhyay, Peter J Turnbaugh, James B Johnson, John C Newman

“…Exploratory outcomes include physical function, cognitive function, quality of life, aging biomarkers and inflammatory measures.…”
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Antiphospholipid antibodies inhibit the migration and invasion of trophoblast cells by suppressing the JNK/C-Jun/MMP1 signaling pathway by Qingchen Wang, Weimin Feng, Yuan Tan, Jiao Qiao, Hongchao Liu, Qi Liu, He Wang, Qian Zhang, Jingjin Tao, Zhongxin Li, Boxin Yang, Zhen Xu, Chong Wang, Shuo Yang, Liyan Cui

“…Therefore, this article aimed to explore the potential mechanisms by which aPL affect trophoblast cell function. Method An APS cell model was established in the HTR-8 trophoblast cell line, followed by RNA sequencing to identify key genes involved in trophoblast cell function. …”
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Investigations of Modified Classical Dynamical Models: Melnikov’s Approach, Simulations and Applications, and Probabilistic Control of Perturbations by Nikolay Kyurkchiev, Tsvetelin Zaevski, Anton Iliev, Vesselin Kyurkchiev, Asen Rahnev

“…We present a few specific modules for examining these oscillators’ behavior. …”
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The role of GATA4 in mesenchymal stem cell senescence: A new frontier in regenerative medicine by M. Arockia Babu, Renuka Jyothi S, Irwanjot Kaur, Sachin Kumar, Naveen Sharma, M. Ravi Kumar, Pranchal Rajput, Haider Ali, Gaurav Gupta, Vetriselvan Subramaniyan, Ling Shing Wong, Vinoth Kumarasamy

“…A better understanding of the molecular mechanisms that underlie GATA4 mediated modulation of MSC senescence would provide an opportunity to develop new therapies to revitalize old MSCs to increase their regenerative function for therapeutic purposes in regenerative medicine.…”
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Regulatory role of CD177+ neutrophils in BMP signaling pathway and its implications for inflammatory bowel disease, sepsis, and intestinal tumors by Lin Yu, Haoyue Zhang, Ling Jia, Detian Lai, Lina Jia, Qingzhu Li, Enwei Guo, Feng Yang, Bingyu Zhang, Qiancheng Luo

“…Weighted gene co-expression network analysis (WGCNA), gene functional enrichment analysis, pan-cancer analysis, single-cell analysis, and in vitro experiments including Caco-2 cell culture, cell proliferation assay (CCK-8), flow cytometry apoptosis analysis, quantitative real-time PCR (qRT-PCR), and plate colony formation assay were performed. …”
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Bionic Intelligent Interaction Helmet: A Multifunctional-Design Anxiety-Alleviation Device Controlled by STM32 by Chuanwen Luo, Yang You, Yan Zhang, Bo Zhang, Ning Li, Hao Pan, Xinyang Zhang, Chenlong Wang, Xiaobo Wang

“…Secondly, it incorporates a real-time interaction function that optimizes the cycling experience while mitigating psychological stress. …”
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Coffee as a Source of Antioxidants and an Elixir of Youth by Zofia Kobylińska, Marek Biesiadecki, Ewelina Kuna, Sabina Galiniak, Mateusz Mołoń

“…This paper highlights the extensive scientific evidence supporting coffee’s ability to combat oxidative stress, enhance cognitive function, and improve metabolic and cardiovascular health. …”
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A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer by Shengyang Qiu, Gianluca Pellino, Francesca Fiorentino, Shahnawaz Rasheed, Ara Darzi, Paris Tekkis, Christos Kontovounisios

“…Neurotensin (NTS) is a physiologically occurring hormone which affects the function of the gastrointestinal (GI) tract. In recent years, NTS, acting through its cellular receptors (NTSR), has been implicated in the carcinogenesis of several cancers. …”
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YOLOv8-LSW: A Lightweight Bitter Melon Leaf Disease Detection Model by Shuang Liu, Haobin Xu, Ying Deng, Yixin Cai, Yongjie Wu, Xiaohao Zhong, Jingyuan Zheng, Zhiqiang Lin, Miaohong Ruan, Jianqing Chen, Fengxiang Zhang, Huiying Li, Fenglin Zhong

“…Finally, WIoUv3 replaces the original loss function, optimizing lesion boundary regression based on a dynamic focusing mechanism. …”
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Decoding the hypoxic tumor microenvironment in colorectal cancer for prognostic modeling and therapeutic target discovery by Xiao-Cui Duan, Yan Zhou, Fan Feng, Hai-Bo Jiang, Mei-Lin Wang, Zhe Han, Hong-Fei Pang, Yu-Hang Liu, Heng-Zhe Jia, Meng- He, Hong-Pan Xu, Yuan-Yuan Wang

“…Finally, in vitro assays assessed the functional role of GIPC2, a model gene, in CRC cell lines.ResultsSingle-cell profiling uncovered eight distinct hypoxic clusters, with H3 exhibiting the highest hypoxia scores and enrichment in glycoprotein metabolic and angiogenesis pathways. …”
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Evaluating the Accuracy and Reliability of Real-World Digital Mobility Outcomes in Older Adults After Hip Fracture: Cross-Sectional Observational Study by Martin A Berge, Anisoara Paraschiv-Ionescu, Cameron Kirk, Arne Küderle, Encarna Micó-Amigo, Clemens Becker, Andrea Cereatti, Silvia Del Din, Monika Engdal, Judith Garcia-Aymerich, Karoline B Grønvik, Clint Hansen, Jeffrey M Hausdorff, Jorunn L Helbostad, Carl-Philipp Jansen, Lars Gunnar Johnsen, Jochen Klenk, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Arne Müller, Lynn Rochester, Lars Schwickert, Kristin Taraldsen, Beatrix Vereijken

“…ObjectiveThis study examined DMO accuracy and reliability in a hip fracture cohort considering walking bout (WB) duration, physical function, days since surgery, and walking aid use. …”
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A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

“…Besides, the Gene Set Enrichment Analysis (GSEA) was used to identify the biological function of DEGs. The interaction between DEGs and the competing endogenous RNAs (ceRNA) network was detected using STRING and visualized using Cytoscape. …”
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Anti-atherosclerotic effects of natural compounds targeting lipid metabolism and inflammation: Focus on PPARs, LXRs, and PCSK9 by Marcella Palumbo, Martina Ugolotti, Francesca Zimetti, Maria Pia Adorni

“…These beneficial outcomes are certainly related to the crucial function of these targets in maintaining cholesterol homeostasis and regulating systemic inflammation. …”
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Development and Delivery of an Integrated Digital Health Care Approach for Children With Juvenile Idiopathic Arthritis: Usability Study by Sonia Butler, Dean Sculley, Derek Santos, Xavier Gironès, Davinder Singh-Grewal, Andrea Coda

“…Physical activity is also encouraged to retain musculoskeletal function. The primary determinants of treatment success are maintaining long-term adherence, ongoing monitoring by a pediatric rheumatologist, and involvement of an interdisciplinary team. …”
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Human-Intelligent Information System Collaboration in Digital Twin Environment: Value Proposition, Key Technologies, and Practical Approaches by Fangrui BAI, Shaobo LIANG, Dan WU, Yuheng REN, Fan YANG

“…[Results/Conclusions] The study shows that human and digital twin systems have different unique values in the whole ecology, the irreplaceable wisdom of the human brain is reflected in innovation and decision-making, and the core function of the digital twin system is to support and enhance the communication between man and machine. …”
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Using the Smath Computer Package in School Mathematics Lessons by Valery F. Ochkov, Inna E. Vasileva, Yuliya V. Shatskikh

“…Scenarios for the application of the package are proposed to develop both basic computational skills and the fundamental skills of solving equations and constructing function graphs. Examples include linear equations and their systems, quadratic equations, equations containing modules, and text problems leading to the construction of equations. …”
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Screening potential diagnostic biomarkers for PLA2R‑associated idiopathic membranous nephropathy by WGCNA analysis and LASSO algorithm by Jinxu Huang, Yaqing Huang, Xiaoling Zeng, Yuhong Zhang, Junneng Zhang, Qingchu Hong, Yongtiao Peng

“…WGCNA filtered PLA2R-related modules and intersected genes. LASSO regression, evaluated by ROC analysis, identified characteristic genes. …”
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Integration of single-cell RNA and bulk RNA sequencing revealed malignant ductal cell heterogeneity and prognosis signatures in pancreatic cancer by Haiyang Du, Haiyang Du, Gao Si, Jiqing Si, Xuejie Song, Xuejie Song, Fuchun Si, Fuchun Si

“…Finally, in vitro knockdown of CTSV assessed its functional role in pancreatic cancer (PAC) cell proliferation and migration.ResultsThree prognosis-related genes—ANLN, NT5E, and CTSV—were selected based on their strong association with clinical stage and validated in external datasets. …”
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Dec2 attenuates autophagy in inflamed periodontal tissues by Shunichi Oka, Xiaoyan Li, Fuyuki Sato, Fengzhu Zhang, Nitesh Tewari, Chongchong Chen, Liangjun Zhong, Makoto Makishima, Yi Liu, Ujjal K. Bhawal

“…Here, we provide a comprehensive functional characterization of periodontal ligament fibroblasts (PDLFs) treated with Porphyromonas gingivalis lipopolysaccharide (LPS), aiming to reveal previously unappreciated biological changes and to investigate how a transcription factor differentiated embryonic chondrocytes 2 (Dec2)‐deficient environment influences the function of autophagy in nflamed human PDLFs. …”
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