Structural design and optimization of egg carrier for dynamic egg slit detection platforms. by Ronghua Meng, Yuxiang Tian, Siwei Huang

“…First, the egg carrier functions are analysed, and preliminary design concepts and solutions are proposed via TRIZ theory. …”
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Exploration of metastasis-related signatures in osteosarcoma based on tumor microenvironment by integrated bioinformatic analysis by Shiyao Liao, Xing Gao, Kai Zhou, Yao Kang, Lichen Ji, Xugang Zhong, Jun Lv

“…DEGs with similar biological functions were grouped into the same module by Gene Ontology (GO) analysis and MCODE analysis. …”
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Role of histone deacetylases and sirtuins in the ischaemic stroke: a protocol for a systematic review and meta-analysis of animal studies by Ali Majdi, Hossein Mostafavi, Ali Moharrami, Shahin Yaraghi, Amirreza Ghaffari Tabrizi, Morteza Dojahani, Erfan Alirezapour, Kamyar Mansori

“…This study aims to provide a comprehensive overview of the function of HDACs and their modulators in the treatment of acute ischaemic stroke.Methods This systematic review and meta-analysis will encompass animal intervention studies that explore the efficacy of modulation of HDACs and sirtuins in the acute phase of ischaemic stroke. …”
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Self-assembled metal clustersomes and chirality transfer to colloidal photonic crystals by Ya-Jie Wang, Ke-Xin Zheng, Yi-He Yu, Zhengkun Xie, Pengyao Xing, Shuang-Quan Zang

“…The characteristic of combining rigidity with soft matter morphology offers opportunities to explore application potentials in colloidal photonic crystals, particularly those with modulated structural colors. Compared with traditional liposomes and polymersomes, metal clustersomes could provide expanded functionalities.…”
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Disentangled similarity graph attention heterogeneous biological memory network for predicting disease-associated miRNAs by Yinbo Liu, Qi Wu, Le Zhou, Yuchen Liu, Chao Li, Zhuoyu Wei, Wei Peng, Yi Yue, Xiaolei Zhu

“…Additionally, various ablation studies were conducted to validate the contributions of different modules within the framework, and’s encoding statuses and memory units of DiGAMN were visualized to explore the utility and functionality of its modules. …”
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Failure Effects Evaluation for ATC Automation System by Rui Li, Zili Zhou, Yansong Cheng, Jianqiang Wang

“…The failure effects evaluation of ATC automation system is aimed at the effects of modules or components which affect the performance and functionality of the system. …”
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Design and Application of Reliability Calculation Program Based on Secondary Development of ABAQUS by ZOU Hong, WU Jian, XU Zhichun, YANG Li

“…As a kind of finite element analysis software,ABAQUS is widely used in nonlinear simulation field,but there is no universal and mature reliability calculation module.Therefore,it is necessary to establish a general reliability calculation program for Monte Carlo simulation based on finite element model to meet the automation requirements of reliability calculation of various structures in ABAQUS.This paper firstly puts forward the design idea and main functions of reliability calculation program in ABAQUS,including random number generation,model batch building,automatic result extraction and so on;then,develops the pre-processing and post-processing modules of ABAQUS with Python language for modularizing the main functions of the program;finally,introduces the application method of this reliability calculation program in detail taking the reliability calculation process of the finite element model of a simply supported steel truss bridge as an example.This reliability calculation program can effectively improve the degree of automation in the process of structural reliability calculation,and reduce the calculation time,which has great reference value in engineering application.…”
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La voie entre Cessero (Saint-Thibéry, Hérault) et Segodunum (Rodez, Aveyron) : lieux d’étape de la moyenne vallée de l’Hérault by Stéphane Mauné

“…Its use was frequent if not systematic, and it included several different modules. It appears to have emerged at the end of the Augustan period and its adoption was associated with a high level of functionality. …”
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Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis by Ji Hui Fan, Xiao Min Li

“…Our study aims to explore the potential functions of mesangial cell-derived circRNAs using RNA sequencing (RNA-seq) and bioinformatics analysis.Methods Mouse mesangial cells (MMCs) were stimulated by lipopolysaccharide (LPS) to establish an in vitro model of CGN. …”
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Betaine Dietary Supplementation: Healthy Aspects in Human and Animal Nutrition by Giovanni Buonaiuto, Alessia Federiconi, Carla Giuditta Vecchiato, Elisa Benini, Attilio Luigi Mordenti

“…In humans, betaine supports hepatic function, cardiovascular health, renal protection, and physical performance, mainly by modulating homocysteine metabolism, lipid profiles, and oxidative stress. …”
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Redox-driven regulation of UCHL3/Yuh1 influences mitochondrial health via the NEDD8/Rub1 pathway by Soha Issa, Yuval Klein, Eden Berda, Shahaf Saad, Yehonatan Sharaby, Moran Benhar, Elah Pick

“…Here, we investigated how changes in the redox state affect Yuh1 catalytic function. Our findings reveal a thiol-based redox switch that modulates Yuh1 catalytic function in response to accumulated ROS. …”
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Neocarzilin A induces apoptosis and mitochondrial disturbance by targeting reticulon 4-mediated endoplasmic reticulum stress by A. T. Jauch, J. Sailer, J. Braun, E. Czeslik, J. Geyer, C. Eberhagen, A. M. Vollmar, H. Zischka, S. A. Sieber, S. Zahler

“…Proteomic ABPP data indicate reticulon 4 (Rtn4, Nogo), an ER-located protein mainly involved in shaping ER tubules and maintaining proper ER function, as a promising hit to explain those effects. …”
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Research on an adaptive multimodal cognitive load classification method by Xiangxin Yu, Ruizhen Wang

“…Purpose: Functional near-infrared spectroscopy (fNIRS) has emerged as a prominent research tool in the fields of brain function analysis, and cognitive load classification due to its ability to objectively reflect cognitive states. …”
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Zebrafish mecp2 null-mutation increases anxiety and cortisol levels but no change in adult social preference and larval chemically-induced hyperlocomotion by Soaleha Shams, Pierre Cronell, Jenny Landin, Thomas Pietri, Adrian Ekehorn Gimdal, Petronella Kettunen, Lars Westberg

“…However, the hyper-locomotion response to PTZ at 5 dpf and social preference for visual social stimulus at 21 dpf and in adulthood were not affected by the lack of functional Mecp2. Conclusions Functional Mecp2 modulated larval locomotion and behavioural anxiety at different ages and adult cortisol levels, but mecp2 null-mutation did not alter adult locomotion and socialization, and developmental sociability and PTZ-induced hyperlocomotion in zebrafish. …”
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The relationships of resting-state brain entropy (BEN), ovarian hormones and behavioral inhibition and activation systems (BIS/BAS) by Donghui Song, Ze Wang

“…Furthermore, they elucidate the neural mechanisms through which PROG modulates impulsivity traits measured by BAS-drive: PROG enhances the temporal coherence (decreased entropy) of neural activity in the left DLPFC, which in turn increases temporal synchronization (increased FC) within this region during resting-state, and then enhances executive control functions, thereby negatively regulating impulsivity. …”
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Self-powered sensing platform based on triboelectric nanogenerators towards intelligent mining industry by Lindong Liu, Yurui Shang, Andy Berbille, Morten Willatzen, Yuan Wang, Xunjia Li, Longyi Li, Xiongxin Luo, Jianwu Chen, Bin Yang, Cuifeng Du, Zhong Lin Wang, Laipan Zhu

“…To address these limitations, we developed a triboelectric self-powered sensing-platform (TESS) employing two distinct triboelectric nanogenerators (TENGs) modules to achieve power generation and wind-speed sensing function, with an ultra-low starting wind speed (0.32 m s−1), capable of operating for up to 3 months in underground mining tunnels. …”
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Targeting YTHDF2 with pH-responsive siRNA nanoparticles suppresses MYC m6A modification and restores antitumor immunity in hepatocellular carcinoma by Ziqi Guo, Qiuling Huang, Zhenzhen Cui, Cheng Yang, Liu Yang

“…Despite increasing interest in MDSC-targeted strategies, effective approaches to selectively modulate MDSC function and enhance immunotherapeutic efficacy remain limited. …”
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Regulatory role of DBC1 in inflammation and autoimmune diseases by Jinzhi Wu, Fan Yang, Guanhua Xu, Xinlei Ma, Jin Lin, Weiqian Chen

“…Our findings indicate that DBC1 exhibits dual pro‐inflammatory and anti‐inflammatory functions, primarily achieved through the direct or indirect modulation of key immunoinflammatory proteins, including silent information regulation 2 homolog‐1, histone deacetylase 3, SUVH9, and signal transducer and activator of transcription (STAT). …”
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Purslane oleracea polysaccharides alleviate male reproductive damage caused by acrylonitrile by improving gut microbiota dysbiosis and metabolic disorder by Weihua Li, Hongbing Li, Jing Wu, Chenggang Jia, Yanli Lei

“…It also holds promise for functional food and drug development.…”
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The Effects of Noxious Electrical Stimulation and Eccentric Exercise on Mechanical and Thermal Pain Sensitivity in Recreational Runners with Achilles Tendinopathy by Scott K. Stackhouse, Brian J. Eckenrode, Kathleen C. Madara

“… # Hypothesis/Purpose The purpose of this study was to describe the changes in pain sensitivity and self-reported function in runners with chronic Achilles tendon pain following sequential treatment with noxious electrical stimulation (NxES) and eccentric plantarflexion exercise…”
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