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5421
Investigating the cognitive architecture of verbal fluency: evidence from an interference design on 487 controls
Published 2024-12-01“…Finally, word production appears to be modulated by different cognitive processes over time, with a prominence of the phonological output lexicon in early production and more demanding processing (i.e., executive functioning) in late production.…”
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5422
Postural Muscle Dyscoordination in Children With Cerebral Palsy
Published 2005-01-01“…This might imply that both stereotypies might be regarded as functional strategies to compensate for the dysfunctional capacity to modulate subtly postural activity.…”
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5423
Analysis and Simulation of Overmodulation Modes of a Three-Inverter Block of the Photovoltaic Installation
Published 2022-08-01“…This goal is achieved by the fact that the process of two-stage control of the system in the zone of overmodulation of inverters is carried out on the basis of synchronized phase shifts between the control signals of inverters (a constant phase shift, as well as an additional adjustable phase shift between the inverter signals as a function of the duration of clock subintervals), with an appropriate modification of the algorithms of synchronous PWM of inverters due to the inclusion of two specialized correction factors in the basic functional dependencies. …”
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5424
Toll-like receptor-mediated immune imbalance in asthma: controversies, breakthroughs, and future directions
Published 2025-07-01“…Therefore, this review sought to examine the functional mechanisms of TLRs and associated signaling cascades in asthma, and explore novel prevention and treatment approaches centered on TLRs modulation.…”
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5425
P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS
Published 2025-08-01“…Here we document the presence of PHB in spermatocytes and its functional roles in meiosis by generating the first male germ cell-specific PhbcKO mouse. …”
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5426
Mesenchymal Stem Cell-Derived Extracellular Vesicles Therapy for Pulmonary Hypertension: A Comprehensive Review of Preclinical Studies
Published 2022-01-01“…MSC-EVs therapies, safer than cell-based treatments, have been shown to be effective in modulating macrophages to support anti-inflammatory phenotypes, which are strongly related to histological and functional benefits in preclinical models of pulmonary hypertension. …”
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5427
Allosteric Lever: Toward a Principle of Specific Allosteric Response
Published 2025-06-01“…Allostery, the phenomenon by which the perturbation of a molecule at one site alters its behavior at a remote functional site, enables control over biomolecular function. …”
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5428
Gut metagenomic features of frailty
Published 2024-11-01“…This signature suggests multiple interconnected mechanisms through which the microbiome may influence frailty development, including modulation of inflammation, alterations in energy metabolism, and potential impacts on muscle function through microbial metabolites.…”
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5429
Beyond negative valence: 2-week administration of a serotonergic antidepressant enhances both reward and effort learning signals.
Published 2017-02-01“…We measured brain activity with functional magnetic resonance imaging (fMRI) in volunteers as they performed a concurrent appetitive (money) and aversive (effort) learning task. …”
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5430
The synergistic extract of Zophobas atratus and Tenebrio molitor regulates neuroplasticity and oxidative stress in a scopolamine-induced cognitive impairment model
Published 2025-04-01“…Moreover, it effectively inhibited senescence in the hippocampus by modulating the AMPK/SIRT and BDNF-Akt/mTOR signaling pathways.DiscussionThis study highlights the promising potential of the ZaTm extract mixture as a novel therapeutic agent and functional food for the prevention and treatment of Alzheimer’s disease and other neurodegenerative disorders.…”
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5431
The Role of Protein–Lipid Interactions in Priming the Bacterial Translocon
Published 2024-11-01“…Protein–lipid interactions demonstrate important regulatory roles in the function of membrane proteins. Nevertheless, due to the semi-liquid nature and heterogeneity of biological membranes, and dissecting the details of such interactions at high resolutions continues to pose a major challenge to experimental biophysical techniques. …”
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5432
Comprehensive SUMO Proteomic Analyses Identify HIV Latency-Associated Proteins in Microglia
Published 2025-02-01“…This modification is essential for modulating immune responses and influencing signaling pathways that govern the activation and function of immune cells. …”
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5433
Analysis of Alternative Splicing Events and Identification of Key Genes in <i>Brassica napus</i> Leaves Infected by <i>Leptosphaeria biglobosa</i>
Published 2024-10-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed to elucidate the biological functions of differentially spliced genes at various time points, while Weighted Gene Co-expression Network Analysis (WGCNA) was used to identify key modules and hub genes. …”
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5434
A Recovery-Oriented Suicide Prevention Program Led by Peer Specialists for Veterans With Serious Mental Illness: Protocol for a Pilot Randomized Controlled Trial
Published 2025-08-01“…This group may also experience cognitive and functional impairments that complicate suicide prevention care. …”
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5435
Software for Graph Analysis and Visualization
Published 2014-12-01“…The developed algorithm for finding communities and implemented algorithms of autolayouts of graphs are the main functionality of the product. The main advantage of the developed software is high speed processing of large size networks (up to millions of nodes and links). …”
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5436
Decoding the FSHR gene: a multi-tool computational approach to SNPs with potential application in PCOS
Published 2025-08-01“…These genetic differences can affect gene function and regulation, thereby influencing individual variations in disease susceptibility, including complex conditions such as PCOS (Polycystic Ovary Syndrome). …”
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5437
PACAP/PAC1 regulation in cystitis rats: induction of bladder inflammation cascade leading to bladder dysfunction
Published 2024-11-01“…Additionally, modulation of the PACAP/PAC1 pathway was tested in rats to determine its effects on bladder inflammation and function.ResultsOur results demonstrate significant upregulation of PACAP and PAC1 in both human bladder tissues from IC/BPS patients and in the rat cystitis model. …”
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5438
Digital teaching resource management system for higher education
Published 2024-12-01“…Abstract At present, the management and utilization of teaching resources in higher education are characterized by issues, such as limited functionality, simple structure, inadequate sharing, and weak management capacity. …”
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5439
Model of quality management in the manufacture of aircraft engines
Published 2020-01-01“…It consists of two main modules that determine the functioning of various information systems and a single data warehouse to support decision making within the framework of a unified system of enterprise quality management. …”
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5440
ENGINEERING TEACHER'S PEDAGOGICAL MASTERY: WAYS TO IMPROVE
Published 2017-10-01“…While solving the problem of the unity and polarity of roles played by a faculty member at an engineering university, such as teacher, researcher, or resource specialist, some questions arise, such as: how can all these teacher's functions be balanced? How can we ensure the efficiency of teaching activity without loss of its integrity? …”
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