Bioactive whey peptides: a bibliometric and functional overview by Eduarda Heck Sumny, Aniela Pinto Kempka

“…Abstract The objective of this research was to examine bioactive peptides derived from whey, focusing on their functional properties and potential applications in food and therapeutics. …”
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Nicotinamide Inhibits CD4+ T-Cell Activation and Function by Lotte Nijhuis, Alejandra Bodelόn, Rianne C. Scholman, Isabelle Houtzager, Lyanne J. P. M. Sijbers, Enric Mocholi, Lucas W. Picavet, Jorg J. A. Calis, Michal Mokry, Sebastiaan J. Vastert, Jorg van Loosdregt

“…Here, we address this gap by investigating how NAM influences CD4+ T-cell activation and function. We also describe that NAM treatment significantly suppresses CD4+ T-cell activation in vitro, as evidenced by impaired proliferation and reduced expression of surface activation markers. …”
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Neural function of Netrin-1 in precancerous lesions of the pancreas by Hiba Haidar, Anaïs Bellon, Karen Sleiman, Mélanie Hocine, Nicolas Rama, Nicolas Gadot, Darren R. Carpizo, Patrick Mehlen, Fanny Mann

“…However, the molecular signals driving this early neuroplasticity and its functional consequences remain poorly understood. Here, we identify the axon guidance molecule Netrin-1 as a key factor secreted by pancreatic cells within precursor lesions of pancreatic cancer. …”
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Quality of Life and Psychological Functioning in Children with PFAPA Syndrome by Xosé Ramón García-Soto, Maria Isabel Villanueva-Alameda, Jessica Fernández-Solana, Jerónimo J. González-Bernal, Arancha Bernal-Jiménez, Lara Santos-Martín, Juan García-Mellado, Sara Calvo-Simal, Rodrigo Vélez-Santamaría

“…The Strengths and Difficulties Questionnaire (SDQ) and the Family Impact Module scale of Pediatric Quality of Life Inventory (PedsQL) were used to assess psychological functioning and HRQoL, respectively. …”
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Functional segregation of rostral and caudal hippocampus in associative memory by Alicia Nunez Vorobiova, Matteo Feurra, Enea Francesco Pavone, Lennart Stieglitz, Lukas Imbach, Victoria Moiseeva, Johannes Sarnthein, Tommaso Fedele, Tommaso Fedele, Tommaso Fedele

“…Given its complexity, the hippocampus participates in multiple aspects of higher cognitive functions, among which are semantics-based encoding and retrieval. …”
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Sphingolipids and mitochondrial function, lessons learned from yeast by Pieter Spincemaille, Bruno P.A. Cammue, Karin Thevissen

“…In summary, recent research shows that S. cerevisiae is an invaluable model to investigate SLs as signaling molecules in modulating mitochondrial function, but can also be used as a tool to further enhance our current knowledge on SLs and mitochondria in mammalian cells.…”
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Osteocalcin and GPR158: linking bone and brain function by Jingjing Li, Shujie Lou, Xuepeng Bian

“…As a critical receptor for OCN, G protein-coupled receptor 158 (GPR158) facilitates the proliferation, differentiation, and survival of neural cells while directly influencing neurons' structural and functional plasticity, thereby modulating cognitive function. …”
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An Integrated Optogenetic and Bioelectronic Platform for Regulating Cardiomyocyte Function by Olurotimi A. Bolonduro, Zijing Chen, Corey P. Fucetola, Yan‐Ru Lai, Megan Cote, Rofiat O. Kajola, Akshita A. Rao, Haitao Liu, Emmanuel S. Tzanakakis, Brian P. Timko

“…Systems that incorporate both modulation of cellular function and recording capabilities can enhance the utility of these approaches and their customization to the needs of each patient. …”
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Follicle architecture and innervation of functionally distinct rat vibrissae by Ben Gerhardt, Tobias Rodde, Jette Alfken, Jakob Reichmann, Tim Salditt, Michael Brecht

“…Establishing how afferent types and accessory structures operate together to derive specific kinds of sensory information has been challenging, because we often lack precise information on afferent types, accessory structures and vibrissa function. Here we address this challenge by synchrotron X-ray imaging of vibrissa follicles of rat vibrissae with distinct function. …”
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Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics by Mengyuan Peng, Niannian Li, Hongbo Wang, Yaxu Li, Hui Liu, Yanhua Luo, Bao Lang, Weihang Zhang, Shilong Li, Liujun Tian, Bin Liu

“…Tissue‐resident macrophages (e.g., Langerhans cells, Kupffer cells, microglia) display unique organ‐specific functions, while inflammatory stimuli drive their polarization into proinflammatory (M1) or anti‐inflammatory (M2) phenotypes along a functional continuum. …”
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Oxidative Stress: Signaling Pathways, Biological Functions, and Disease by Sixuan Liu, Jiachen Liu, Yinhuai Wang, Fei Deng, Zebin Deng

“…ABSTRACT The dysregulated accumulation of reactive oxygen species (ROS) and reactive nitrogen species disrupts redox homeostasis, triggering oxidative stress (OS) and driving pathophysiological changes across multiple organ systems. OS modulates critical signaling pathways, induces inflammation, impairs mitochondrial function, alters metabolic homeostasis, and dysregulates autophagy, contributing to disease progression. …”
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Pattern recognition receptors: function, regulation and therapeutic potential by Ruochan Chen, Ju Zou, Jiawang Chen, Xiao Zhong, Rui Kang, Daolin Tang

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Multiple functional neurosteroid binding sites on GABAA receptors. by Zi-Wei Chen, John R Bracamontes, Melissa M Budelier, Allison L Germann, Daniel J Shin, Krishnan Kathiresan, Ming-Xing Qian, Brad Manion, Wayland W L Cheng, David E Reichert, Gustav Akk, Douglas F Covey, Alex S Evers

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Use of Carbon Nanotubes for the Functionalization of Concrete for Sensing Applications by Xiaohui Jia, Anna Lushnikova, Olivier Plé

“…This study advances the development of self-sensing concrete through functionalization with carbon nanotubes (CNTs) for structural health monitoring. …”
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The biogenesis, regulation and functions of transitive siRNA in plants by Tan Huijun, Liu Yuelin, Guo Hongwei

“…Members of this class of siRNAs function in various biological processes ranging from development to stress adaptation. …”
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Flavonoids and anxiety: decoding their role in brain function and pathophysiology by Riya Singla, Sonia Kamboj, Brijesh Kumar Duvey, Anurag Bhargava, Jasmine Chaudhary

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BOD1 Is Required for Cognitive Function in Humans and Drosophila. by Sahar Esmaeeli-Nieh, Michaela Fenckova, Iain M Porter, M Mahdi Motazacker, Bonnie Nijhof, Anna Castells-Nobau, Zoltan Asztalos, Robert Weißmann, Farkhondeh Behjati, Andreas Tzschach, Ute Felbor, Harry Scherthan, Seyed Morteza Sayfati, H Hilger Ropers, Kimia Kahrizi, Hossein Najmabadi, Jason R Swedlow, Annette Schenck, Andreas W Kuss

“…Together our results reveal novel postmitotic functions of BOD1 as well as pathogenic mechanisms that strongly support a causative role of BOD1 deficiency in the aetiology of intellectual disability. …”
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Effective connectivity analysis of response inhibition functional network by Monica Di Giuliano, Andy Schumann, Feliberto de la Cruz, Pedro Henrique Rodrigues Da Silva, Karl-Jürgen Bär

“…Finally, correlation analyses between self-reported impulsivity levels and causal network interactions revealed that highly impulsive individuals require greater interhemispheric integration between the right and left ECNs for effective inhibition, as well as a causal excitatory modulation from the right executive control network (rECN) to the vDMN.DiscussionIn summary, our study reveals complex hierarchical dynamics among functional networks during response inhibition. …”
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Exofection by exosomes: A transient functional cargo transfer by Ramkumar Menon, Madhuri Tatiparthy, Jessica Selim, Isidore Mushimiyimana, Brinley Harrington, Awanit Kumar, Lauren Richardson, Emmanuel Amabebe, Ananth Kumar Kammala

“…In each scenario, the donor cells' exosomal cargo modulates recipient cell functions, promoting tissue repair, immune regulation, or metastasis. …”
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Reduction of Glucocorticoid Receptor Function in Chronic Fatigue Syndrome by Megan Lynn, Laura Maclachlan, Andreas Finkelmeyer, James Clark, James Locke, Stephen Todryk, Wan-Fai Ng, Julia L. Newton, Stuart Watson

“…GR function can be estimated ex vivo by measuring dexamethasone (dex) modulation of cytokine response to lipopolysaccharide (LPS), and in vivo using the impact of dex on cortisol levels. …”
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