From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines by Fengyan Deng, Valentina Peña, Pedro Morales-Sosa, Andrea Bernal-Rivera, Bowen Yang, Shengping Huang, Sonia Ghosh, Maria Katt, Luciana Andrea Castellano, Lucinda Maddera, Zulin Yu, Nicolas Rohner, Chongbei Zhao, Jasmin Camacho

“…These cells exhibit frequent spontaneous contractions, suggesting robust functional integrity at the neuromuscular junction. …”
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Novel multi-omics analysis revealing metabolic heterogeneity of breast cancer cell and subsequent development of associated prognostic signature by Peng Zhang, Cuicui Li, Fen Li, Jiezhong Wu, Kunpeng Hu, He Huang

“…Drug sensitivity prediction was performed via the OncoPredict tool. Functional assays investigated the oncogenic role of PDCD1 in breast cancer cell lines. …”
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Ketogenic diet, adenosine, and dopamine in addiction and psychiatry by David N. Ruskin, Luis A. Martinez, Susan A. Masino

“…Adenosine represents a unique and direct link among cell energy, neuronal activity, and gene expression, and adenosine receptors form functional heteromers with dopamine receptors. The importance of the dopaminergic system is established in addiction, as are the challenges of modulating the dopamine system directly. …”
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Identification of key biomarkers of the glomerulus in focal segmental glomerulosclerosis and their relationship with immune cell infiltration based on WGCNA and the LASSO algorithm by Yun Xia Zhang, Juan Lv, Jun Yuan Bai, XiaoWei Pu, En Lai Dai

“…MCODE identified five modules. The turquoise module of WGCNA had significant relevance to the glomerulus in FSGS. …”
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Development and Investigation of Vision System for a Small-Sized Mobile Humanoid Robot in a Smart Environment by Amer Tahseen Abu-Jassar, Hani Attar, Ayman Amer, Vyacheslav Lyashenko, Vladyslav Yevsieiev, Ahmed Solyman

“…To ensure the high speed of the computer vision system based on the ESP32-CAM module, the neural network was improved by replacing the Visual Geometry Group 16 (VGG-16) network as the base network for extracting the functions of the Single Shot Detector (SSD) network model with the tiny-YOLO lightweight network model, which made it possible to preserve the multidimensional structure of the network model feature graph, resulting in increasing the detection accuracy, while significantly reducing the amount of calculations generated by the network operation, thereby significantly increasing the detection speed, due to a limited set of objects. …”
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The potential crosstalk genes and molecular mechanisms between systemic lupus erythematosus and periodontitis by Kai Zhao, Xiaolong Li, Qingmiao Zhu, Mengyu Zhu, Jinge Huang, Ting Zhao

“…Finally, levels of immune cell infiltration in SLE and PD were assessed using CIBERSORTx.ResultsA total of 50 core genes were identified between the genes screened by WGCNA and DEGs. Functional enrichment analysis revealed that these genes are primarily associated with the PI3K-Akt and B-cell receptor signaling pathways. …”
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The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility in Oryza sativa L by Yusheng Xu, Yusheng Xu, Dingyang Yuan, Meijuan Duan

“…This system comprises three modules: first, a dominant nuclear male-sterile (NMS) functional module driven by p5126, designed to achieve the dominant nuclear male-sterile trait; second, a fluorescence-based selection module driven by the endosperm-specific promoter LTP2, which facilitates the expression of the red fluorescent protein gene DsRed; and finally, a herbicide resistance screening module driven by the constitutive CaMV35S promoter, enabling the expression of the selectable marker Bar gene. …”
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Comparative Analysis of Microbial–Short-Chain Fatty Acids–Epithelial Transport Axis in the Rumen Ecosystem Between Tarim Wapiti (<i>Cervus elaphus yarkandensis</i>) and Karakul She... by Jianzhi Huang, Yueyun Sheng, Xiaowei Jia, Wenxi Qian, Zhipeng Li

“…Core microbiota analysis identified <i>Bacteroidetes</i> (relative abundance: 52.3% vs. 48.1%), <i>Prevotellaceae</i> (22.7% vs. 19.4%), and <i>Prevotella</i> (18.9% vs. 15.6%) as dominant taxa in both species, with significant enrichment of <i>Bacteroidetes</i> in wapiti (<i>p</i> < 0.01). Functional annotation (PICRUSt2) demonstrated enhanced glycan biosynthesis (KEGG ko00511), DNA replication/repair (ko03430), and glycoside hydrolases (<i>GH20</i>, <i>GH33</i>, <i>GH92</i>, <i>GH97</i>) in wapiti (FDR < 0.05). …”
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AI-powered visual E-monitoring system for cattle health and wealth by Aung Si Thu Moe, Pyke Tin, Masaru Aikawa, Ikuo Kobayashi, Thi Thi Zin

“…The system employs a multi-camera setup, comprising RGB, RGB-D, and ToF depth cameras, strategically deployed across four functional zones of a cattle barn: the milking parlor, return lane, feeding area, and resting space. …”
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Assessing usability of electronic patient-reported outcome measures in older people with and without a rare dermatologic disorder by Calvin N. Ho, Anna Kündig, Lila Bahadori, Katy Roat, Rachel Bruce, Caroline P. Goswami, Kimberly Kelly, Thomas Moll

“…These results can be leveraged to improve clinical data recording, optimize device usability, and enhance the user experience for older people and those with functional or physical limitations. Graphical abstract…”
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Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction by Fang Lyu, Yuxin Zhong, Qingliu He, Wen Xiao, Xiaoping Zhang

“…Gene expression was confirmed in ccRCC cell lines (786-O, Caki-1) and tumor tissues. Functional assays, such as wound healing and Transwell assays, were employed to evaluate tumor invasion and migration. …”
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Prediction of Alzheimer’s Disease Based on Multi-Modal Domain Adaptation by Binbin Fu, Changsong Shen, Shuzu Liao, Fangxiang Wu, Bo Liao

“…<b>Background/Objectives:</b> Structural magnetic resonance imaging (MRI) and 18-fluoro-deoxy-glucose positron emission tomography (PET) reveal the structural and functional information of the brain from different dimensions, demonstrating considerable clinical and practical value in the computer-aided diagnosis of Alzheimer’s disease (AD). …”
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Identification of Diagnostic Biomarkers and Therapeutic Targets in Sepsis-Associated ARDS via Combining Bioinformatics with Machine Learning Analysis by Liu T, Gao L, Li X

“…Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analysis and immune infiltration analysis. …”
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Integrated Analysis to Reveal Heterogeneity of Tumor‐Associated Neutrophils in Glioma by Wen Wang, Junsheng Li, Qiheng He, Chenglong Liu, Siyu Wang, Zhiyao Zheng, Bojian Zhang, Siqi Mou, Wei Sun, Jizong Zhao

“…In vitro experiments were also performed for functional verification, including CCK8, EdU, Transwell, and TUNEL assays. …”
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Shared pyroptosis pathways and crosstalk genes underpin inflammatory links between periodontitis and atherosclerosis by Pinxin Zhan, Zhiying Feng, Xinqi Huang, Haoyang Xu, Shijun Xu, Shan Wang

“…Following batch effect correction and normalization, differential expression analysis was conducted using the limma package in R. Functional enrichment analysis was performed with the clusterProfiler package to identify key pathways, while heatmaps and pathway networks were constructed to visualize the relationships among pyroptosis genes and crosstalk genes. …”
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Multi-Omics Analysis Provides New Insights into the Interplay Between Gut Microbiota, Fatty Acid Metabolism, and Immune Response in Cultured and Wild <i>Coilia nasus</i> from the Y... by Chang Yang, Kai Liu, Yanmin Deng, Qianhui Wang, Shiqian Cao, Qunlan Zhou

“…Modular analysis identified five modules linked to immune functions and fatty acid metabolism. …”
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BSCL2 and CDK5 are two genes associated with circadian rhythm disturbance in Parkinson’s disease by Dongdong Chen, Qingqing Huang, Ming Ye

“…We then conducted weighted gene co-expression network analysis on this dataset to select the most significant modules (turquoise modules) and took the intersection of the two to obtain crossover genes (85 genes), which were functionally enriched in the Disease Ontology (DO), Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Acute stress-induced alterations in short-chain fatty acids: Implications for the intestinal and blood brain barriers by Cristina Rosell-Cardona, Sarah-Jane Leigh, Emily Knox, Emanuela Tirelli, Joshua M. Lyte, Michael S. Goodson, Nancy Kelley-Loughnane, Maria R. Aburto, John F. Cryan, Gerard Clarke

“…Microbially-produced metabolites such as short-chain fatty acids (SCFA) are key effectors within the gut-brain axis which can affect gut and brain function. The aim of this work is to determine if acute stress regulates SCFA production in the gut and to understand the associated implications for gastrointestinal and brain barrier function. …”
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Visual three-dimension finite-element analysis system (CPFEM) and its engineering application by SHEN Xiao-wen, WANG Fu-xi, QIAN Xiang-qun, SHI Wei

“…The visual three-dimension finite-element analysis system (CPFEM) was developed, Which consisted of the modules with 15 nodes, 20 nodes, 8 nodes and 6 nodes respectively, a auto-dissecting module for some special parts (CPPIP), an interface module with SAP5M and ADINATM (CPCPP), and a post-processing module. …”
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Rice Leaf Disease Image Enhancement Based on Improved CycleGAN by YAN Congkuan, ZHU Dequan, MENG Fankai, YANG Yuqing, TANG Qixing, ZHANG Aifang, LIAO Juan

“…Ablation studies were further performed to validate the effectiveness of the CBAM residual module and the perception similarity loss function in the network's overall architecture. …”
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