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5301
Application of the Rehabilitation Principle of "GU ZHENG (Bones Integrity) and JIN HE (Muscles Harmony), XING SHEN GONG TIAO (Union of Body and Mind)" in Chronic Musculoskeletal Dy...
Published 2023-02-01“…The function of Gu is to provide structural support and stability. …”
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5302
Abnormal neuronal activity in the subthalamic nucleus contributes to dysarthria in patients with Parkinson's disease
Published 2025-04-01“…Background: This study investigated the subthalamic nucleus (STN) function and deep brain stimulation (DBS) effects on single-unit activity (SUA) in Parkinson's disease (PD) patients with dysarthria. …”
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5303
Brain-acting hepatokines: its impact on energy balance and metabolism
Published 2025-05-01“…The liver is recognized for its central role in energy metabolism, yet emerging evidence highlights its function as an endocrine organ, secreting a variety of proteins—hepatokines—that influence distant tissues. …”
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5304
Security monitoring via sound analysis and voice identification with artificial intelligence
Published 2024-08-01“…Successful correct recognition of the test voice profiles on access and security personalization with a quantitative equivalent of 100.0 % accuracy was achieved in the Linear transfer function for Cascade-Forward Neural Networks. The proposed method and the synthesized neural models in the research can be used as units and modules in access control systems with biometric diagnostics and intelligent recognition of employees in company departments to electronically store classified information and physical access control.…”
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5305
Rapid Prediction of Multi-physics Coupling in Heat Pipe ReactorBased on Neural Network
Published 2024-06-01“…In the process of multi-physics coupling, there exists a sophisticated iterative mechanism, wherein the computational analyses of distinct physical domains largely function autonomously. When contemplating the integration of neural network paradigms as surrogates within the multi-physics coupling framework, it is pivotal to target the numerical computations intrinsic to individual physical domains. …”
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5306
TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis
Published 2024-11-01“…We have identified a novel function of the p53 family protein TAp73 in regulating mitochondrial dynamics. …”
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5307
Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching
Published 2025-05-01“…Introduction: Sympathetic hyperinnervation plays an important role in modulating the vascular smooth muscle cell (VSMC) phenotype and vascular diseases, but its role in abdominal aortic aneurysm (AAA) is still unknown. …”
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5308
CLINICAL EXPERIENCE OF USING THE DRUG CELLEX IN PATIENTS WITH VESTIBULAR SYNDROME
Published 2021-11-01“…Chronic cerebral ischemia with predominantly vertebrobasilar insufficiency is a reversible violation of cerebral function caused by a decrease in blood circulation in the vertebral system and the main arteries. …”
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5309
ATP6AP1 drives pyroptosis-mediated immune evasion in hepatocellular carcinoma: a machine learning-guided therapeutic target
Published 2025-04-01“…Pyroptosis is a form of cell death with complex dual functions in tumor immunity. However, the precise regulatory mechanisms and interactions between pyroptosis and immune evasion in HCC remain poorly understood. …”
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5310
Machine Learning in Cyber-Physical Systems and Manufacturing Singularity – it Does Not Mean Total Automation, Human Is Still in the Centre: Part I – Manufacturing Singularity and a...
Published 2020-12-01“…Based on the exposed considerations, a generic architecture of intelligent CPS, with embedded ML functional modules in multiple learning loops, in order to evaluate way of use of ML functionality in the context of CPPS/CPS. …”
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5311
RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11
Published 2022-01-01“…The findings were validated using a dual-luciferase reporter assay and western blotting. The functional genes of the PI3K/AKT/mTOR signaling pathway were identified, and the functional significance of miR-7-5p in AML cells was determined using a functional recovery assay. …”
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5312
Direct analytical efficiency assessment of the NaI(Tl) gamma-ray detector (Romashka)
Published 2025-01-01“…The present study focuses on the analytical and numerical calculations of the solid angle, effective solid angle, efficiency, and gamma-ray average path length within the detector materials as a function of the source position. This analysis is conducted for a Romashka module of the 4p NaI(Tl) gamma-ray detector array (NaGRaDA). …”
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5313
Ferroptosis in Cancer: Epigenetic Control and Therapeutic Opportunities
Published 2024-11-01“…This review delves into the epigenetic mechanisms that modulate ferroptosis in cancer cells, focusing on how DNA methylation, histone modifications, and non-coding RNAs influence the expression and function of essential genes involved in this process. …”
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5314
PIPNet: A Deep Convolutional Neural Network for Multibaseline InSAR Phase Unwrapping Based on Pure Integer Programming
Published 2025-01-01“…Then, we innovatively designed a new joint loss function and PIP constraints to guide the iterative optimization of model parameters. …”
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5315
Multi-Scale Long- and Short-Range Structure Aggregation Learning for Low-Illumination Remote Sensing Imagery Enhancement
Published 2025-01-01“…., local continuity) structures distributed across different scales of each input LI image to build an appropriate deep mapping function from the LI images to their corresponding high-quality counterparts. …”
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5316
Insight into the effects of Omega-3 fatty acids on gut microbiota: impact of a balanced tissue Omega-6/Omega-3 ratio
Published 2025-05-01“…Emerging evidence suggests that Omega-3 polyunsaturated fatty acids (PUFAs) are essential structural and functional nutrients that significantly influence the composition and function of the gut microbiota, a key mediator of host health. …”
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5317
Signal processing of little elements monopulse direction finder in the conditions of strong interference using neural networks
Published 2019-06-01“…The results of comparative analysis of the accuracy of direction finding of the useful signal achieved by using neural network and statistical algorithms of functioning are presented.…”
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5318
Actin isoforms and neoplastic transformation
Published 2017-04-01“…The major goal of the research was to elucidate the function of the actin isoforms during motile activities, adhesions and cell division and to investigate whether their expression and/or structural organization is related to pathological function. …”
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5319
MARC, a novel modular chimeric antigen receptor, improves T cell-based cancer immunotherapies by preventing early T cell exhaustion and enhancing persistence
Published 2025-04-01“…We hypothesized that these limitations arise because current CAR architectures fail to replicate the modular design of native activating immune receptors, which integrate distinct receptor and signaling modules. This modular assembly is crucial for maintaining proper receptor regulation and function.Methods Therefore, we set forth to develop a modular chimeric antigen receptor leveraging the same assembly principles found in native activating immune receptors to reestablish the intrinsic safeguards in receptor expression and signaling.Results The resulting Modular Actuation Receptor Complex (MARC) displayed surface expression levels akin to its native immune receptor counterpart, the NK cell receptor KIR2DS3, while eliminating tonic signaling. …”
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5320
The role of the contralesional primary motor cortex in upper limb recovery after stroke: a scoping review following PRISMA-ScR guidelines
Published 2025-05-01“…Animal studies provided evidence of structural and functional plasticity, including dendritic remodeling and enhanced neuronal connectivity, which paralleled improvements in motor function. …”
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