Epimedin C enhances mitochondrial energy supply by regulating the interaction between MIC25 and UBC in rodent model. by Mi Huang, Lei Yu, Zhong Li, Ying Wang, Chunlin Yang

“…Using C57BL/6 mice, we demonstrate that Epimedin C enhances exercise performance through preservation of mitochondrial function. Proteomic analysis identified MIC25 as a key protein modulated by Epimedin C, whose stability is regulated via ubiquitin-dependent degradation. …”
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Organization of electronic archive based on TOFI Platform by F. Ismagulova, M. Gabbasov, A. Toybekov

“…This article examines the main functionality and modules of a typical electronic archive on the TOFI Platform that can be used as a standard solution for electronic archives for universities and institutes based on KazRENA…”
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Design of an Intelligent Active Surveillance and Early Warning System for Infectious Diseases by Min Liu, Wannian Liang, Jian Hu, Liangyu Kang, Wenzhan Jing, Kangning Cai, Xiaopeng Qi, Debing Liu, Quanyi Wang

“…The proposed system encompasses four key functional modules: multi-channel active surveillance, intelligent early warning, data-driven risk assessment, and smart response and evaluation. …”
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A dual-reporter LDLR system integrating fluorescence and luminescence for understanding LDLR regulation and facilitating drug discovery by Peng Jiao, Peng Jiao, Peng Jiao, Peng Jiao, Na Yang, Na Yang, Qianfeng Jia, Baozhen Fan, Ke Feng, Ke Feng, Jian Yu, Shengtian Zhao, Shengtian Zhao, Shengtian Zhao

“…Additionally, screening for transcriptional regulators identified FOXP3 and CREB as novel modulators of LDLR expression, with CREB-mediated regulation involving the sterol regulatory element-binding protein 2 (SREBP2) pathway.DiscussionThis dual-reporter system enables complementary monitoring of LDLR dynamics, providing enhanced sensitivity, accuracy, and versatility for studying LDLR regulation and function, as well as facilitating drug discovery targeting hyperlipidemia and cardiovascular diseases.…”
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Dynamic Coordination of Alternative Splicing and Subgenome Expression Bias Underlies Rusty Root Symptom Response in <i>Panax ginseng</i> by Jing Zhao, Juzuo Li, Xiujuan Lei, Peng Di, Hongwei Xun, Zhibin Zhang, Jian Zhang, Xiangru Meng, Yingping Wang

“…Integrative analysis of differentially expressed genes uncovered 671 loci under dual regulation; functional classification categorized these genes in receptor-like kinase signaling and chromatin-remodeling modules, underscoring the synergy between AS and transcriptional control. …”
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A Novel Triboelectric–Electromagnetic Hybrid Generator with a Multi-Layered Structure for Wind Energy Harvesting and Wind Vector Monitoring by Jiaqing Niu, Ribin Hu, Ming Li, Luying Zhang, Bei Xu, Yaqi Zhang, Yi Luo, Jiang Ding, Qingshan Duan

“…The TEHG comprises three functional layers corresponding to three modules: a soft-contact rotary triboelectric nanogenerator (S-TEHG), an electromagnetic generator (EMG), and eight flow-induced vibration triboelectric nanogenerators (F-TENGs), which are arranged in a circular array to enable low-wind-speed energy harvesting and multi-directional wind vector monitoring. …”
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Game-based visual feedback-guided dynamic balance training versus conventional training in patients with hemiplegia: a pilot randomized controlled trial by Yan Xu, Jiadong Ni, Yajing Yang, Jiajia Yao, Lianhui Fu, Cong Xu

“…The post-training assessment revealed significant improvements (Berg Balance Scale, Functional Reaching Test, Timed “Up-and-Go” Test scores and 10-metre fast walking speed) in outcome measures in the full sample. …”
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Integrative analysis of bulk and single-cell transcriptomic data reveals novel insights into lipid metabolism and prognostic factors in hepatocellular carcinoma by Feiyu Qi, Guiming Zha, Yanfang Zhang, Sihua Liu, Yuhang Yang, Wanliang Sun, Dongdong Wang, Zhong Liu, Zheng Lu, Dengyong Zhang

“…A weighted gene co-expression analysis of all genes of the bulk transcriptome samples revealed the correlation between gene modules and risk score. Genes with cor > 0.4 in the highest-expressing module were selected for Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functional enrichment analysis. …”
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A Data Storage, Analysis, and Project Administration Engine (TMFdw) for Small- to Medium-Size Interdisciplinary Ecological Research Programs with Full Raster Data Capabilities by Paulina Grigusova, Christian Beilschmidt, Maik Dobbermann, Johannes Drönner, Michael Mattig, Pablo Sanchez, Nina Farwig, Jörg Bendix

“…Over almost 20 years, a data storage, analysis, and project administration engine (TMFdw) has been continuously developed in a series of several consecutive interdisciplinary research projects on functional biodiversity of the southern Andes of Ecuador. …”
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Integrative bioinformatic analysis identifies differentially expressed gene targets as potential biomarkers for anaplastic thyroid cancer by Angel Sebastian Treviño-Juarez, Jose Gerardo Gonzalez-Gonzalez, Rene Rodriguez-Gutierrez, Adriana Sanchez-Garcia, Camilo Daniel Gonzalez-Velazquez

“…Differentially expressed genes (DEGs) were identified using GEO2R, and overlapping genes across datasets were detected through Venn diagram analysis. Functional enrichment was performed using DAVID and Metascape. …”
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Teaching Bioinspired Design for Assistive Technologies Using Additive Manufacturing: A Collaborative Experience by Maria Elizete Kunkel, Alexander Sauer, Carlos Isaacs, Thabata Alcântara Ferreira Ganga, Leonardo Henrique Fazan, Eduardo Keller Rorato

“…This initiative illustrates how biomimetic mechanisms and design can be integrated into education to generate functional outcomes and socially impactful health technologies. …”
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Proteomic profiling of plasma extracellular vesicles identifies signatures of innate immunity, coagulation, and endothelial activation in septic patients by Chanhee Park, Taekyung Ryu, Rashida Mohamed-Hinds, Kyungdo Kim, Jin Hyeok Kim, Lin Zou, Brittney Williams, Chan Hyun Na, Wei Chao

“…The KEGG analysis of the DE proteins revealed multiple functional pathways linked to sepsis, e.g., complement/coagulation, platelet activation, phagosome, inflammation, and neutrophil extracellular trap formation. …”
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Retinoid X receptor γ regulates epithelial–mesenchymal transition and tumor immune infiltration in papillary thyroid cancer tumorigenesis: an experimental and in silico study by Pihong Li, Wei Zhang, Qiaolin Wu, Xiaohua Zhang, Zhouci Zheng

“…Objective: This study aimed to elucidate the functional role and underlying molecular mechanisms of retinoid X receptor γ (RXRG) in the pathogenesis of papillary thyroid carcinoma (PTC). …”
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Enhancing operational efficiency and financial reporting through Oracle NetSuite ERP implementation: A case study in a logistics company by Stepani Sisca Wulandari, Kevin Maulana

“…The study highlights the benefits and challenges associated with implementing ERP systems, emphasizing the importance of aligning the chosen ERP system with the organizational functionalities, culture, strategy, and structure. Also, the modules within Oracle NetSuite, including Procure To Pay, Inventory, Fixed Asset, and General Ledger, are explained, along with their respective functionalities. …”
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Extraction, structure, activity and application of konjac glucomannan by Qiurui Hu, Gangliang Huang, Hualiang Huang

“…It contains various bioactive components, the most notable of which is konjac glucomannan, which has several biological roles, including efficiently fighting diabetes, exerting prebiotic activity, containing antioxidant capacity, modulating immunological function, and demonstrating anti-cancer potential. …”
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Remote Monitoring System of Patient Status in Social IoT Environments Using Amazon Web Services Technologies and Smart Health Care by Amer Tahseen Abu-Jassar, Hani Attar, Ayman Amer, Vyacheslav Lyashenko, Vladyslave Yevsieiev, Ahmed Solyman

“…The authors advocate using the accomplished system for functional diagnostics specialists, paramedics, and cardiologists in medical facilities and the military medical system for rapid diagnosis and direct monitoring of troops’ health state on the battlefield.…”
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HSD²Former: Hybrid-Scale Dual-Domain Transformer with Crisscrossed Interaction for Hyperspectral Image Classification by Binxin Luo, Meihui Li, Yuxing Wei, Haorui Zuo, Jianlin Zhang, Dongxu Liu

“…HSD²Former consists of three functional modules: dual-dimension multiscale convolutional embedding (D²MSCE), mixed domainFormer (MDFormer), and pyramid scale fusion block (PSFB). …”
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Experimental Investigation and Simultaneous Optimisation of Honing Parameters of Dry Cast Iron Cylinder Relining Sleeves of Motor Vehicle Engine Blocks for Surface Finish and Energ... by Nicholas Tayisepi, Lameck Mugwagwa, Albert Mnkandla, Innocent Mapindu, Takudzwa Muhla

“…Machining based manufacturing industries consume significant amounts of electrical energy, to power the several modules constituting the machine tool, with low levels of efficiency. …”
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Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia. by Ignat Drozdov, Bernhard Svejda, Bjorn I Gustafsson, Shrikant Mane, Roswitha Pfragner, Mark Kidd, Irvin M Modlin

“…The network was confirmed to be non-random, scale-free, and highly modular. Functional analysis of gene co-expression modules revealed processes including 'Nervous system development', 'Immune response', and 'Cell-cycle'. …”
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Infrastructure for Digital Pasture-Based Livestock Production in Arid Zones by S. S. Dorzhiev, E. G. Bazarova

“…(Conclusions) The modular architecture of the proposed system enables flexible integration of various technologies and functional units, adaptable to the specific needs of local production conditions. …”
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