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4661
Integration of ordered porous materials for targeted three-component gas separation
Published 2025-01-01“…Thermodynamic and dynamic simulation results explained that the pre-designed pore modules can perform specific target functions independently in the pore-integrated materials.…”
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4662
Synergizing Multi-Temporal Remote Sensing and Systemic Resilience for Rainstorm–Flood Risk Zoning in the Northern Qinling Foothills: A Geospatial Modeling Approach
Published 2025-06-01“…This framework quantitatively evaluates the nonlinear response mechanisms of town–village systems to flood disasters, emphasizing the synergistic effects of spatial scale, morphology, and functional organization. The proposed framework uniquely integrates three innovative modules: (1) a hybrid risk identification engine combining normalized difference vegetation index (NDVI) temporal anomaly detection and spatiotemporal hotspot analysis; (2) a morpho-functional resilience quantification model featuring a newly developed spatial morphological resilience index (SMRI) that synergizes landscape compactness, land-use diversity, and ecological connectivity through the entropy-weighted analytic hierarchy process (AHP); and (3) a dynamic scenario simulator embedding rainfall projections into a coupled hydrodynamic model. …”
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4663
Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy
Published 2025-05-01“…IntroductionSmall cell lung cancer (SCLC) remains a leading cause of cancer mortality worldwide, characterized by rapid progression and poor clinical outcomes, and the function of metabolic reprogramming remains unclear in SCLC.MethodsWe performed multi-omics analysis using public SCLC datasets, analyzing single-cell RNA sequencing to identify metabolic reprogramming patterns between chemotherapy-resistant and sensitive samples. …”
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4664
Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol
Published 2022-07-01“…The intervention group will receive a newly developed 6-week novel custom-made SP-VR application comprising two sessions weekly. Three SP-VR modules will cover key aspects of survivors’ social health needs, namely functional rehabilitation, social participation, and social interaction and recreation. …”
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4665
Machine learning identifies lipid-associated genes and constructs diagnostic and prognostic models for idiopathic pulmonary fibrosis
Published 2025-07-01“…WGCNA revealed that the blue module was strongly associated with IPF and served as the core module. …”
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4666
Evolutionarily stable gene clusters shed light on the common grounds of pathogenicity in the Acinetobacter calcoaceticus-baumannii complex.
Published 2022-06-01“…We delineate gene clusters in the type strain A. baumannii ATCC 19606 whose evolutionary conservation indicates a functional integration of the subsumed genes. These evolutionarily stable gene clusters (ESGCs) reveal metabolic pathways, transcriptional regulators residing next to their targets but also tie together sub-clusters with distinct functions to form higher-order functional modules. …”
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4667
Automatic Semifluid Mass Dispenser
Published 2023-03-01“…The article discusses the genesis of the project, the functional and technical assumptions of the innovative device, as well as the design and development of the prototype and performance of functional tests, paying particular attention to the presentation and description of the following: (1) the original structural solutions; (2) the operation of functional modules that are responsible for positioning and identifying dye tubes, dispensing dyes in precisely defined amounts, monitoring the composition of the colour formula, and ensuring optimum dye use; and (3) the user interface. …”
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4668
Network features of the mammalian circadian clock.
Published 2009-03-01“…The use of multiple doses powered the analysis to uncover several novel network features of the circadian clock, including proportional responses and signal propagation through interacting genetic modules. We also observed several examples where a gene is up-regulated following knockdown of its paralog, suggesting the clock network utilizes active compensatory mechanisms rather than simple redundancy to confer robustness and maintain function. …”
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4669
Single-cell Analysis Highlights Anti-apoptotic Subpopulation Promoting Malignant Progression and Predicting Prognosis in Bladder Cancer
Published 2025-02-01“…Protein-protein interaction (PPI) network analysis identified functional modules related to apoptosis, proliferation, and metabolism in the anti-apoptotic subpopulation. …”
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4670
Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties.
Published 2012-02-01“…Members of the myomesin protein family function as molecular bridges that connect major filament systems in the central M-band of muscle sarcomeres, which is a central locus of passive stress sensing. …”
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4671
A target detection model HR-YOLO for advanced driver assistance systems in foggy conditions
Published 2025-04-01“…Furthermore, The Wise Intersection over Union (WIoU) loss function is introduced to enhance target localization accuracy. …”
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4672
Methods and algorithms of intellectual support in making managerial decisions in the implementation of security alarm tasks at objects of special importance
Published 2024-01-01“…Currently, there is a problem of developing low-cost and functional SOTC controllers with support for algorithms for controlling the totality of elements of life support systems and subsystems of HMB OOV, for example, access control and management systems (ACS), as well as the possibility of integrating the proposed SOTC solutions into existing HMB facilities. …”
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4673
COUNTERREENGINEERING OF ELECTRONIC DEVICES
Published 2019-02-01“…Methods and means of special design reengineering of functional modules of multilayer printed circuit boards and case microcircuits are presented. …”
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4674
斜齿椭圆齿轮CAD系统的研究
Published 2014-01-01“…The design methods and calculation equation of the helical elliptical gears are studied.Then a helical elliptical gears CAD system is built through secondary development of SolidWorks software by using VB 6.0which is a visual and object-oriented program language.By using this system,the 3Dparametric modeling and dynamic meshing simulation of helical elliptical gears is achieved and these problems such as complex calculations and 3Ddesign are solved.The specific process,composition,function of main modules and the realization of the system are introduced,and finally,the functionality of this CAD system is verified by an example of a pair of three order helical elliptical gear3Dmodeling and dynamic meshing simulation.…”
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4675
Analysis of human brain RNA-seq data reveals combined effects of 4 types of RNA modifications and 18 types of programmed cell death on Alzheimer’s disease
Published 2025-04-01“…Abstract Background RNA modification plays a critical role in Alzheimer’s disease (AD) by modulating the expression and function of AD-related genes, thereby affecting AD occurrence and progression. …”
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4676
Research on Soft PLC System of Open CNC
Published 2017-12-01“…Furthermore,it can achieve the function to control logic instruction function of open architecture CNC system.…”
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4677
A Fog Computing-Based Cost-Effective Smart Health Monitoring Device for Infectious Disease Applications
Published 2024-10-01“…All these sensor modules are connected to a fog computing device, namely a Raspberry PI microcontroller. …”
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4678
Single-cell transcriptional landscape of peripheral myeloid cells in autoimmune diseases
Published 2025-08-01“…Through pseudotime analysis, we identified a branching process leading to two intermediary inflammatory subtypes and observed dysregulation in eight co-expression modules crucial for monocyte function across autoimmune conditions. …”
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4679
A Scripting Language for Embedded Software Automatic Test
Published 2019-01-01“…In addition, based on the established use-case model, nested execution of use cases is used to solve the problem of uncertainty of test results caused by the interaction of functional modules. This method is validated by establishing an automatic test system for safety equipment of train, which satisfies the input of test scripts written in natural language and the test of complex coupling and correlation functions.…”
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4680
NUF2 is associated with cancer stem cell characteristics and a potential drug target for prostate cancer
Published 2024-12-01“…Next, we explored the potential function of the modules and genes obtained using WGCNA using an enrichment analysis. …”
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