Construct Validity and Internal Consistency of the Italian Version of the PedsQL^TM 4.0 Generic Core Scale and PedsQL^TM 3.0 Cerebral Palsy Module by Ilaria Pedrinelli, Sofia Biagi, Domenico Marco Romeo, Elisa Musto, Valeria Fagiani, Martina Lanza, Erika Guastafierro, Alice Colombo, Andrea Giordano, Cristina Montomoli, Cristiana Rezzani, Tiziana Casalino, Eugenio Mercuri, Daria Riva, Matilde Leonardi, Giovanni Baranello, Emanuela Pagliano

“…In CwCP, greater functional disability resulted in lower HRQoL scores, and there was significant discrepancy between the parent and child ratings.…”
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RHO-Associated Coiled-Coil-Containing Protein Kinase Inhibitors Significantly Modulate the Epithelial–Mesenchymal Transition Induced by TGF-β2 in the 2-D and 3-D Cultures of Human... by Araya Umetsu, Yosuke Ida, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

“…Results: Exposure to 5 nM of the transforming growth factor beta2 markedly increased the trans-endothelial electrical resistance values as well as the metabolic function in two-dimensional cultures of human corneal stroma fibroblasts. …”
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Complexity in cancer biology: is systems biology the answer? by Evangelia Koutsogiannouli, Athanasios G. Papavassiliou, Nikolaos A. Papanikolaou

“…Abstract Complex phenotypes emerge from the interactions of thousands of macromolecules that are organized in multimolecular complexes and interacting functional modules. In turn, modules form functional networks in health and disease. …”
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Cure the Incurable: Update of Treatment in Inherited Neuromuscular Disorders by Cheng-Hao Yu, Kuan-Lin Lai

“…Approaches aiming to rescue the underlying pathophysiology, i.e. loss-of-function or gain-of-function mutations, have been developed via end-product replacement or gene delivery/modulation, with promising results. …”
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Il funzionamento della personalità secondo il DSM-5: DPA e SCID-5-AMPD by 1 Laura Rapanà, 2 Claudio Barbaranelli

“…On one hand, we used the Dimensional Personality Assessment Test, filled out directly by the patient in self-assessment; on the other hand, we used the structured clinical interview for the Level of Personality Functioning Scale - Module I, included in the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorder-5 Alternative Model for Personality Disorders, performed by the clinician to the patient. …”
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The effect of pump laser pulse chirp on the properties of generated nonlinear Thomson scattering radiation by Zi Wang, Junyuan Xu, Jiachen Li, Qianmin Zheng, Youwei Tian

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Next-generation probiotics: Advancements in fermented dairy products and their health benefits by Aqsa Ajmal, Jixia Yang, Rimsha Ajmal, Md. Zobair Al Mahmud

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Elexacaftor/Tezacaftor/Ivacaftor Efficacy in a Cohort of Italian Patients with CFTR Rare Mutations by Francesca Lucca, Sonia Volpi, Mirco Ros, Benedetta Fabrizzi, Ilaria Meneghelli, Marica Bordicchia, Francesca Buniotto, Alessia Lancini, Cecilia Brignole, Francesca Pauro, Valentino Bezzerri, Marco Cipolli

“…Background: Cystic Fibrosis is an inherited disorder caused by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (<i>CFTR</i>) gene, encoding a chloride and bicarbonate channel widely expressed in epithelia. Loss of CFTR function leads to dehydration of the epithelium surface with thicker mucus secretions from tissues. …”
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NFIC suppressed the epithelial ovarian cancer via modulating the balance of PTEN/TGFβ1/EGR1/BRD4 and SP1/EZH2 induced Inhibition of TBX2/MMPs signaling by Yanan Ren, Ren Xu, Di Zhang, Luyang Su, Ying Jin, Na Li, Yazhuo Wang

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Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor mi... by Sang Hoon Lee, Jonghwa Won, Sora Kim, Wonjun Son, Yangsoon Lee, Yelim Park, Kyeong-Su Park, Hyunseong Youn, Arim Seo, Byungje Sung

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Reinventing gut health: leveraging dietary bioactive compounds for the prevention and treatment of diseases by Qiurong Wang, Qiurong Wang, Hui Huang, Hui Huang, Ying Yang, Xianglan Yang, Xuemei Li, Wei Zhong, Biao Wen, Feng He, Feng He, Jun Li, Jun Li

“…These metabolites are crucial for gut homeostasis, influencing gut barrier function, immune responses, energy metabolism, anti-inflammatory processes, lipid digestion, and modulation of gut inflammation. …”
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Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism by Boram Seo, Mi Young Lim

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Thylakoids for enhanced photodynamic therapy in hypoxic tumours by Tong Yin, Jingyu Liu, Yue Wu, Xiaobo Peng, Zhibin Hao, Jingxi Zhang, Xianbao Zhan

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Characterization of T cells in the progression of dry eye disease using single-cell RNA sequencing in mice by Zhizhi Zhang, Liwei Zhang, Baihua Chen

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Method for suppressing range sidelobes of bistatic integrated sensing and communication signal based on LFM by JI Chenxing, LI Peng, ZHANG Tianxiang, GAO Yulong

“…By employing performance metrics such as ambiguity function and bit error rate, and through comparative simulation analysis, the feasibility and effectiveness of the optimization methods were verified.…”
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Bi-Interfacial Electron Modulation in Co₉S₈/FeCoS₂ Heterostructures Anchored on Bamboo-Derived Carbon Quasi-Aerogel for High-Performance Hydrogen E... by Wenjing He, Jianliang Cao, Xinliang Zhou, Ning Zhang, Yuzhu Qi, Jin Li, Naiteng Wu, Xianming Liu

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Whale optimized routing path selection and 128 bit secured key management for maritime safety by Arumugam Maharajan, Parasuraman Kumar

“…These parameters are sensed through ship-attached sensors, and further transmitted to the cloud via an Internet of Things (IoT) Module. To optimize the efficiency of this data transfer to the cloud, the proposed work employs a Whale Optimization Algorithm-based Radial Basis Function Neural Network (WOA-RBFNN). …”
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A Small-Sized Unit for the Restoration of Mountain Grasslands by S. I. Bideev, L. R. Gulueva

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Computationally Efficient and Loss-Minimizing Model Predictive Control for Induction Motors in Electric Vehicle Applications by Carolina Nicolás-Martín, Miguel E. Montilla-DJesus, David Santos-Martín, Jorge Martínez-Crespo

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Recent advances in Polygonatum sibiricum polysaccharides: structural insights, bioactivities in Vitro and in Vivo, and therapeutic potential in human and animal models – A review by Mohamed E. Abd El-Hack, Hassan A. Rudayni, Ahmed K Aldhalmi, Abdullah S. Alawam, Ahmed A. Allam, Mohammad M.H. Khan, Asmaa F. Khafaga

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