Effect of Electroacupuncture Treatment at Dazhui (GV14) and Mingmen (GV4) Modulates the PI3K/AKT/mTOR Signaling Pathway in Rats after Spinal Cord Injury by Ke Li, Juntong Liu, Liangyu Song, Wei Lv, Xi Tian, Zhigang Li, Suhua Shi

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Flow-Dependent Modulation of Endothelial Ca²⁺ Dynamics by Small Conductance Ca²⁺-Activated K⁺ Channels in Mouse Carotid Arteries by Mark S. Taylor, Michael Francis, Chung-Sik Choi

“…Background: Small conductance Ca²⁺ activated K⁺ channels (K_Ca2.3) are important regulators of vascular function. They provide Ca²⁺-dependent hyperpolarization of the endothelial membrane potential, promoting agonist-induced vasodilation. …”
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PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB–p65/NLRP3 pathway by Rui Fang, Yan Cheng, Ping Chen, Jing Hu, Liqi Yang

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Modulation of senescent Lepr+ skeletal stem cells via suppression of leptin-induced STAT3‒FGF7 axis activation alleviates abnormal subchondral bone remodeling and osteoarthritis pr... by Fu-Hao Yu, Bo-Feng Yin, Ming-Yu Liu, Wen-Jing Zhang, Zhi-Dong Zhao, Lei Wang, Xiao-Tong Li, Pei-Lin Li, Zhi-Ling Li, Run-Xiang Xu, Li Ding, Heng Zhu

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Chicken meat hydrolysate improves acetaminophen-induced liver injury by alleviating oxidative stress via modulation in Keap1/Nrf2/HO-1 signaling in BALB/c mice by Vipul Wayal, Zhuo-En Tsai, Yu-Hsuan Lin, Yi-Hsuan Lai, Shulhn-Der Wang, Chang-Chi Hsieh

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Astragalus polysaccharides protect against Di-n-butyl phthalate-induced testicular damage by modulating oxidative stress, apoptosis, and the PI3K/Akt/mTOR pathway in rats by Manal R. Bakeer, Seham Samir Soliman, Omaima Ahmed, Fady Sayed Youssef, Ghada E. Ali, Nada H. Aljarba, George D. Zouganelis, Maha M. Rashad

“…Biochemical, histological, and molecular analyses were conducted to evaluate testicular function, oxidative stress markers, and gene expression.ResultsDBP exposure significantly decreased serum testosterone levels, catalase (CAT) activity, lactate dehydrogenase (LDH) activity, and sperm quality, while increasing malondialdehyde (MDA) levels and apoptotic markers Casp3, Casp9. …”
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Neuroprotective and anticonvulsant effect of trimetazidine in a PTZ-kindling model of mice through modulation of the IL-1β/IL-1R1 and HMGB-1/TLR-4 axis by Shahnawaz Ahmad, Mohammed Samim, Seema Jain, Divya Vohora, Nidhi

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Modulation of cognitive activity by plant-based extracts (Allium cepa, Coffea robusta, and Brassica oleracea) through the phosphodiesterase 4B inhibition: Insite from a Mice model... by Nazir Ahmad, Kaisun Nesa Lesa, Nanang Fakhrudin, Zullies Ikawati

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PYY-mediated appetite control and obesity alleviation through short-chain fatty acid–driven gut-brain axis modulation by Lacticaseibacillus rhamnosus HF01 isolated from Qula by Y. Sun, D. Li, L. Zhao, X. Liu, K. Guan, Y. Ma, R. Wang, Q. Li

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Oligochitosan Mitigates <i>Vibrio harveyi</i> Infection in Hybrid Groupers (<i>Epinephelus lanceolatus</i> ♂ × <i>Epinephelus fuscoguttatus</i> ♀) by Modulating Immune Responses an... by Fei Shi, Lixin Ma, Zhilong Chen, Hao Zhao, Cuiyun Zou, Li Lin, Zhendong Qin

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Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omics and experimental va... by Rui Hou, Wei Song, Yi Nan, Yiyi Gong, Jieying Liu, Jialin Liu

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Deubiquitylases MoUbp12 and MoUbp14 modulated by transcription factor MoMsn2 are critical for mitochondrial fusion/fission balance and infectious growth of the rice blast fungus by Xingyu Wang, Yuhan Xiao, Qi Li, Lele Xu, Yayuan Huang, Muxing Liu, Xinyu Liu, Zhengguang Zhang, Haifeng Zhang

“…In particular, it plays a significant role in modulating mitochondrial fission and fusion, which are essential for maintaining cellular energy balance and function. …”
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Trypanosoma cruzi Mexican Strains Differentially Modulate Surface Markers and Cytokine Production in Bone Marrow-Derived Dendritic Cells from C57BL/6 and BALB/c Mice by Cecilia Gomes Barbosa, Tamires Marielem Carvalho Costa, Chamberttan Souza Desidério, Paula Tatiana Mutão Ferreira, Mariana de Oliveira Silva, César Gómez Hernández, Malú Mateus Santos, Rafael Obata Trevisan, Weslley Guimarães Bovi, Virmondes Rodrigues, Juliana Reis Machado, Luiz Eduardo Ramirez, Carlo José Freire de Oliveira, Marcos Vinícius da Silva

“…Here, we evaluated whether Ninoa and INC5 strains evaded the immunity of their hosts by modulating the biology and function of murine DCs. The CL-Brener strain was used as the reference strain. …”
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TssI2-TsiI2 of Vibrio fluvialis VflT6SS2 delivers pesticin domain-containing periplasmic toxin and cognate immunity that modulates bacterial competitiveness by Yuanming Huang, Yu Han, Zhenpeng Li, Xiaorui Li, Zhe Li, Ping Liu, Xiaoshu Liu, Qian Cheng, Fenxia Fan, Biao Kan, Weili Liang

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Radar signal recognition exploiting information geometry and support vector machine by Yuqing Cheng, Muran Guo, Limin Guo

“…Abstract Aiming at the recognition of low‐probability‐of‐intercept (LPI) radar signals, a support vector machine (SVM)‐based algorithm is proposed, where the information geometry theory is utilised to optimise the kernel function of the SVM. Since signals with different modulations have different characteristics in the time‐frequency domain, the time‐frequency transformation result of the LPI radar signal is considered as an image, referred to as the time‐frequency image, and computer vision techniques are utilized to perform recognition. …”
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Foreign object detection for mining conveyor belts based on YOLOv5n-CND by SUN Aoran, ZHAO Peipei, YANG Di, ZHANG Junyi, YU Hongjian

“…Second, the normalized Gaussian Wasserstein distance (NWD) regression loss function was used to replace CIoU, improving the performance of multi-scale foreign object detection and accurately predicting the detection of adhering small objects. …”
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Applying shape grammar and BIM for generating the mass modular housing design in ShanLiChenJia village, ZhaoYuan, China by Jiang Wang, Jiandong Zhou, Sheng Zhang

“…The modular building is composed of several component modules, and shape grammar can manipulate their graphics and functions to enrich the combination relationship between component modules. …”
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The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism by Mai-dong Li, Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan, Yue-yin Pan

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Role of vitamin D in the pathogenesis of early-onset preeclampsia: a narrative review by Shu Zheng, Shuai Dong, Huimin Shen, Peng Xu, Chang Shu

“…Despite extensive research, the etiology of EOPE remains unclear, though emerging evidence suggests that vitamin D (VD) may play an important role in placental development and function. Recent studies associate VD deficiency with adverse pregnancy outcomes, including EOPE, through mechanisms such as impaired trophoblast invasion and immune dysregulation at the maternal-fetal interface. …”
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Exploring the Analgesic Potential of L-Lysine: Molecular Mechanisms, Preclinical Evidence, and Implications for Pharmaceutical Pain Therapy by Walaa Alibrahem, Nihad Kharrat Helu, Gréta Törős, Csaba Oláh, József Prokisch

“…Studies in animal models have shown that the administration of lysine reduces pain responses without altering motor function. Despite the favorable profile of lysine in terms of minor side effects and its promising effectiveness as a nutritional supplement, more research is needed to optimize its efficacy, adjust its dosage, and ensure its safety for long-term use.…”
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