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Advances in Functionalized Nanoparticles for Osteoporosis Treatment
Published 2025-06-01“…This review examines the various types and architectures of functionalized nanoparticles, emphasizing their unique capabilities in targeting bone tissue and modulating bone metabolism. …”
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402
Functions of Macrophages in the Maintenance of Intestinal Homeostasis
Published 2019-01-01“…Understanding the mechanisms employed by intestinal macrophages in mediating intestinal immune homeostasis and inflammation, as well as the mode of action of dietary nutrients in the modulating functions of intestinal macrophages, represents an opportunity to prevent and control inflammatory bowel diseases.…”
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403
Effects of bacteriophages on gut microbiome functionality
Published 2025-12-01“…Bacteriophages may regulate the relative abundance of bacterial communities, affect bacterial functions in various ways, and modulate mammalian host immunity. …”
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404
The Role of Apelin in the Functioning of the Reproductive System
Published 2019-07-01Get full text
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405
Bilinear Multipliers on Banach Function Spaces
Published 2019-01-01“…Let X1,X2,X3 be Banach spaces of measurable functions in L0(R) and let m(ξ,η) be a locally integrable function in R2. …”
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406
Optogenetic control of mitochondrial aggregation and function
Published 2025-01-01“…Our functional experiments demonstrate that Opto-MitoA-induced mitochondrial aggregation potently alleviates niclosamide-caused cell dysfunction in ATP production. …”
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407
APPROXIMATE INTEGRATION OF HIGHLY OSCILLATING FUNCTIONS
Published 2017-07-01“…Elementary approximate formulae for numerical integration of functions containing oscillating factors of a special form with a parameter have been proposed in the paper. …”
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408
The Role of Tau in Neuronal Function and Neurodegeneration
Published 2025-05-01“…Tau protein plays a pivotal role in maintaining neuronal structure and function through its regulation of microtubule stability and neuronal polarity. …”
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The effect of cognitive function heterogeneity on depression risk in older adults: a stratified analysis based on functional status
Published 2025-08-01“…BackgroundsThe mechanisms linking depression and cognitive decline in older adults in the context of global aging are unclear, and functional status may modulate the relationship. This study aimed to reveal the heterogeneity of cognitive functioning in older adults under different physical functional states through latent profile analysis (LPA) and to explore the patterns associated with depressive symptoms.MethodsBased on the China Health and Retirement Longitudinal Study (CHARLS) 2020 data, 4,158 older adults ≥60 years old were included, and the subtypes of cognitive functions (immediate memory, delayed memory, calculative ability, orientation, and visual construction) were classified by LPA. …”
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412
Lactobacillus reuteri DSM 17,938 ameliorates LPS-induced depression-like and anxiety-like behaviors by modulating gut microbiota and brain metabolic function
Published 2025-08-01“…In contrast, L. reuteri DSM 17,938 administration restored neural homeostasis, as evidenced by KEGG functional enrichment analysis identifying activated amino acid metabolism and unsaturated fatty acid metabolism pathways. …”
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Type I Interferon Modulates the Function of Ly6C High-Expressing Naïve CD8<sup>+</sup> T Cells to Promote an Antitumor Response
Published 2025-02-01“…This study investigates the functional impact of Ly6C expression on CD8<sup>+</sup> T cells and explores albumin-conjugated IFNβ (Alb-IFNβ) as a strategy to modulate Ly6C expression and improve cancer vaccine efficacy. …”
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415
Role of Adenosine A2A Receptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease
Published 2010-01-01“…The crucial role of adenosine A2ARs in the maintenance of synaptic functions and BDNF levels will be reviewed here and discussed in the light of possible implications for Huntington's disease therapy, in which a joint impairment of BDNF and A2ARs seems to play a pathogenetic role.…”
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416
Cerebral perfusion as a modulator of structural-functional coupling and depressive symptoms: a blue-green light intervention study on subjective memory complaints in women
Published 2025-12-01“…In the right ventral tegmental area (VTA)-right lobule III of cerebellar hemisphere (CER3) edge (ΔCBF in VTA: ΔF = 13.625, p = 0.008; ΔCBF in CER3: ΔF = 23.584, p = 0.002), the intralaminar of thalamus (tIL)-VTA edge (ΔCBF in tIL: ΔF = 22.768, p = 0.002) and the left pulvinar lateral of thalamus (tPuL)-VTA edge (ΔCBF in tIL: ΔF = 11.835, p = 0.011), significant moderation effects of ΔCBF were found.Conclusion Our findings suggested that alterations of CBF might be critical modulating factors, interacting with the structural-functional coupling characteristics of light-sensitive pathways and ultimately regulating depressive symptoms. …”
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Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Atopic Dermatitis Symptoms in Mice through Modulating Immune Balance and Skin Barrier Function
Published 2022-01-01“…In conclusion, SHEDs attenuated AD-like skin lesions in mice by modulating the immune balance and skin barrier function. …”
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Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.
Published 2015-01-01“…Following on these observations, we further assessed the link between the AURKA-HMMR-TPX2-TUBG1 functional module and risk of breast cancer in BRCA1 or BRCA2 mutation carriers. …”
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