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Synergistic Neuroprotection Through Epigenetic Modulation by Combined Curcumin-Enriched Turmeric Extract and L-Ascorbic Acid in Oxidative Stress-Induced SH-SY5Y Cell Damage
Published 2025-03-01“…Its multifaceted neuroprotective properties make it a promising functional ingredient in functional foods for neurodegenerative disease intervention. …”
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4162
Nano selenium in broiler feeding: physiological roles and nutritional effects
Published 2024-11-01“…Nutrition of permitted and optimal levels is very important in the consumption of nano selenium form and as it can have significant beneficial functional and health effects, in case of errors in the selected levels and doses, irreparable side effects and adverse results can occur. …”
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4163
Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration
Published 2025-01-01“…These findings underscore the dual functional capabilities of the LiCS cement in enhancing osteogenesis and modulating the immune environment, making it a promising material for bone tissue engineering and regeneration.…”
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4165
Lane detection based on IBN deep neural network and attention
Published 2022-12-01“…Lane detection is an indispensable technology for environmental perception and is a function of autonomous vehicles. Although many researchers have applied deep learning to lane detection and achieved good results, their application scenarios were relatively simple. …”
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4166
Transient Stability Assessment of Power Systems Built upon Attention-Based Spatial–Temporal Graph Convolutional Networks
Published 2025-07-01“…In addition, an adaptive focal loss function is designed to enhance the fitting of unstable samples and increase the weight of misclassified samples, thereby improving global accuracy and reducing the occurrence of missed instability samples. …”
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4167
The impact of gut microbial short-chain fatty acids on colorectal cancer development and prevention
Published 2025-12-01“…Cancer is a long-term illness that involves an imbalance in cellular and immune functions. It can be caused by a range of factors, including exposure to environmental carcinogens, poor diet, infections, and genetic alterations. …”
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4168
Oxidative Stress and Cancer: Harnessing the Therapeutic Potential of Curcumin and Analogues Against Cancer
Published 2023-12-01“…Reactive oxygen species (ROS) are a class of bioactive molecules that are the by-products of many cellular functions. These molecules are present in normal cells at homeostatic levels but have been studied extensively in cancer due to their dysregulation resulting in pro- and anti-tumorigenic environments. …”
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4169
Lightweight detection model for safe wear at worksites using GPD-YOLOv8 algorithm
Published 2025-01-01“…Furthermore, we adopt an Exponential Moving Average (EMA) SlideLoss function, which not only boosts accuracy but also ensures the stability of our safety wear detection model’s performance. …”
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4171
Power Line Segmentation Algorithm Based on Lightweight Network and Residue-like Cross-Layer Feature Fusion
Published 2025-06-01“…Finally, the Mish activation function is applied in deep convolutional layers to maintain feature extraction accuracy and mitigate overfitting. …”
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4172
About Possibility of Remote Diagnostics of the Respiratory System by Auscultation
Published 2020-06-01“…To avoid discrepancies in the diagnostic results the technical characteristics of the module elements must be normalized. Unified software is required for the module to function. …”
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4173
Integrated Approaches to Managing Cystic Fibrosis: From Nutritional Optimization to Therapeutic Advancements
Published 2024-12-01“…The prevalence of CFRD and CFLD significantly impacts CF management, necessitating regular screening and appropriate treatments. CFTR modulator therapies have led to improvements in lung function and nutritional status, though regular monitoring is essential to prevent complications such as hypervitaminosis, altered lipid metabolism, and insulin sensitivity.Conclusion: A proactive, individualized approach to nutritional management is essential in CF, emphasizing early intervention, regular screening, and personalized therapy to address the diverse challenges faced by these patients.…”
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4174
High-frequency repetitive transcranial magnetic stimulation protects against 6-OHDA-induced Parkinson’s disease symptoms by modulating the proNGF-p75NTR-sortilin pathway
Published 2025-07-01“…The decrease in proNGF-p75NTR-sortilin expression following HF rTMS correlated with a significant increase in DA neuron survival and motor function improvement. HF rTMS exhibited no effects on proBDNF expression. …”
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4175
Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review
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4176
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4177
From Digestion to Detoxification: Exploring Plant Metabolite Impacts on Insect Enzyme Systems for Enhanced Pest Control
Published 2025-04-01“…It highlights the dual function of antioxidative enzymes in detoxifying harmful plant-derived compounds while preserving cellular stability. …”
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4178
EEG-SymNet: multi-channel EEG signal-based schizophrenia diagnosis using channel recalibration and symmetric spatial temporal transformer network
Published 2025-09-01“…Schizophrenia is a severe mental disorder characterized by distorted thinking, perceptions, emotions, and behavior, which can significantly impair an individual’s ability to function in daily life. Early and effective diagnosis is crucial, as it enables timely intervention, which can improve outcomes and reduce the burden on patients and healthcare systems. …”
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4179
Targeted modulation of MMP9 and GRP78 via molecular interaction and in silico profiling of Curcuma caesia rhizome metabolites: A computational drug discovery approach for cancer th...
Published 2025-01-01“…The research targets key cancer-associated proteins, Matrix Metalloproteinase-9 (MMP9) and Glucose-Regulated Protein 78 (GRP78), identified through expression analysis, functional network mapping, and pathway enrichment as critical mediators of cancer progression and metastasis. …”
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