Methylation-modulated PFTK1 regulates gefitinib resistance via Wnt/β-catenin signaling in EGFR mutant non-small-cell lung cancer cells by Xiaoting Jia, Jingjie Tian, Pingping Chen, Jing Dong, Lei Li, Danyang Chen, Jianlei Zhang, Dongjiang Liao, Zhimin He, Kai Luo

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Docosahexaenoic acid-rich fish oil prevented insulin resistance by modulating gut microbiome and promoting colonic peptide YY expression in diet-induced obesity mice by Wanxiu Cao, Fang Liu, Robert W. Li, Yaoxian Chin, Yuming Wang, Changhu Xue, Qingjuan Tang

“…DHA-FO also altered gut microbial function (e.g. “linoleic acid metabolism”) associated with PYY expression (r > 0.80, P < 0.05). …”
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The RELN heterozygous single-nucleotide polymorphism rs362691 increases the prefrontal cortical thickness and modulates systemizing-related autistic tendencies in typically develop... by Hiroki Sato, Hiroki Sato, Hiroki Sato, Mitsunari Abe, Mitsunari Abe, Hikaru Takeuchi, Hiroaki Tomita, Shigeo Kure, Shigeo Kure, Ryuta Kawashima, Yasuyuki Taki

“…Animal and human studies suggest that insufficient reelin signaling due to RELN mutations may alter the functional properties of the prefrontal cortex and contribute to cortical dysplasia in the frontal and temporal lobes. …”
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Lupus nephritis serum induces changes in gene expression in human glomerular endothelial cells, which is modulated by L-sepiapterin: implications for redox-mediated endothelial dys... by Jim C Oates, Dayvia A Russell, Margaret Markiewicz, Justin P Van Beusecum, Sandra M Sanchez, Jeremy L Barth

“…Endothelial nitric oxide synthase (eNOS) plays a modulating role in LN, as genetic ablation of the eNOS enzyme worsens disease. …”
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Transplantation of gastric epithelial mitochondria into human gastric cancer cells inhibits tumor growth and enhances chemosensitivity by reducing cancer stemness and modulating ga... by Hsin-Yi Tsai, Kuen-Jang Tsai, Deng-Chyang Wu, Yaw-Bin Huang, Ming-Wei Lin

“…The mitochondrial metabolic function of gastric cancer cells was determined via a Seahorse bioanalyzer, and extracellular lactate was evaluated via bioluminescent assay. …”
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Extracorporeal ultrasound exposure by the low-frequency acoustic amplitude-modulated signal on a ureteral stent for preventing its incrustation: experimental determination of optim... by A. Yu. Tsukanov, D. S. Akhmetov, A. A. Novikov, N. A. Negrov, A. R. Putintseva, S. P. Semikina

“…The pulsed mode of the device function is most safe. The optimal application points of the instrument emitter for the ureteral upper and middle thirds is the posterior axillary line, and for the ureteral lower third is the middle axillary line.…”
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Variations in flanking or less conserved positions of Reb1 and Abf1 consensus binding sites lead to major changes in their ability to modulate nucleosome sliding activity by Fernanda Raiqueo, Roberto Amigo, José L. Gutiérrez

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LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial-mesenchymal transition by modulating miR-27b-3p by Yuhui Zhao, Zhihang Zhang, Yi Zheng, Huiming Bai, Xiaotong Wu, Yantao Yang, Junfeng Zhang, Chao Yu

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Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a ran... by Masoud Nasiri, Amirabbas Monazzami, Solmaz Alavimilani, Zatollah Asemi

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CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulatin...

“…Additional genetic variants modulating the coagulation cascade may influence bleeding severity. …”
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Multi‐Institutional Phase II Study on the Efficacy and Safety of Dynamic Tumor‐Tracking, Moderately Hypofractionated Intensity‐Modulated Radiotherapy in Patients With Locally Advan... by Michio Yoshimura, Masahiro Hiraoka, Masaki Kokubo, Takashi Sakamoto, Katsuyuki Karasawa, Yukinori Matsuo, Mitsuhiro Nakamura, Nobutaka Mukumoto, Satoshi Morita, Takashi Mizowaki

“…A linac system, which was mounted with a gimbal function, was used for DTT‐IMRT. The prescribed dose was 48 Gy in 15 fractions. …”
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Integrated Transcriptomic and Machine Learning Analysis Identifies EAF2 as a Diagnostic Biomarker and Key Pathogenic Factor in Parkinson&rsquo;s Disease by Peng H, Cheng Y, Chen Q, Qin L

“…Additionally, RT-qPCR experiments were conducted to validate our findings in clinical specimens. Functional enrichment analysis and Gene Set Enrichment Analysis (GSEA) were performed to explore the functional and pathway mechanisms of the identified genes in PD. …”
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Leonurine (SCM-198) exerts protective effects on pancreatic β-cells in type 1 diabetes by modulating the Bax/Bcl-2/Caspase-3 signaling pathway by Zhiqi Li, XiaoRan Liu, FuJiang Wen, WenGuo Jiang, ZhenHong Xia

“…In vivo experiments, SCM-198 could not only reduce the fasting blood glucose (FBG), area under the glucose curve, blood lipid, liver function, and oxidative stress level in T1DM model mice, but also effectively improve the histopathological changes of pancreas and aorta. …”
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AFF4 promotes tumor progression and cisplatin resistance by modulating the PTEN/PI3K/AKT/mTOR axis to accelerate glycolysis in lung adenocarcinoma by Xufeng Yao, Qian Chai, Yuhao Ma, Guomeng Li, Tiantian Jia, Xiaohang Zhang, Tao Xia, Xiaozheng Wei, Xueyi Feng, Yanke Zhang, Yaqiang Zhang, Xueqin Wang, Danye Han, Zongwei Li, Lei Zhao, Qian Dai

“…Changes in cell proliferation, migration, and invasion were determined using in vitro and in vivo loss- and gain-of-function assays. Additionally, glycolysis levels were assessed using metabolite determination assays of glucose and lactate. …”
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Reducing Cd Uptake by Wheat Through Rhizosphere Soil N-C Cycling and Bacterial Community Modulation by Urease-Producing Bacteria and Organo-Fe Hydroxide Coprecipitates by Junqing Zhang, Shuangjiao Tang, Hao Wei, Lunguang Yao, Zhaojin Chen, Hui Han, Mingfei Ji, Jianjun Yang

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Postural correlates of pleasant landscapes visual perception by Mbarka Akounach, Thierry Lelard, Harold Mouras

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Cognitive and anti-inflammatory effects of Palmaria palmata in a schizophrenia mouse model: insights into CREB signaling, Iba-1 expression, and CD4+ cell modulation by Shimaa Mohammad Yousof, Shimaa Mohammad Yousof, Shimaa Mohammad Yousof, Badrah S. Alghamdi, Badrah S. Alghamdi, Thamer Alqurashi, Mohammad Zubair Alam, Mohammad Zubair Alam, Reham Tash, Reham Tash, Reham Tash, Noha M. Abd El-Fadeal, Noha M. Abd El-Fadeal, Samy A. Abusikkien, Samy A. Abusikkien, Lamis Kaddam, Lamis Kaddam

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Genome-wide profiling of micro-RNA expression in gefitinib-resistant human lung adenocarcinoma using microarray for the identification of miR-149-5p modulation by Yong Hu, Xiaobing Qin, Dali Yan, Haixia Cao, Leilei Zhou, Fan Fan, Jialan Zang, Jie Ni, Xiaoyue Xu, Huanhuan Sha, Siwen Liu, Shaorong Yu, Jianzhong Wu, Rong Ma, Jifeng Feng

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The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevan... by Irene Cipollone, Irene Cipollone, Vittoria Monaco, Vittoria Monaco, José Britto-Júnior, Antonio Tiago Lima, Edson Antunes, Andre Sampaio Pupo, Ilaria Iacobucci, Ilaria Iacobucci, Flora Cozzolino, Flora Cozzolino, Maria Monti, Maria Monti, Silvia Parisi, Giuseppina Divisato, Emanuela Cascone, Alfonso De Simone, Angela Corvino, Ferdinando Fiorino, Francesco Frecentese, Vincenzo Santagada, Beatrice Severino, Rosa Sparaco, Pierfrancesco Cinque, Stefania Vertuccio, Giuseppe Caliendo, Gilberto De Nucci, Gilberto De Nucci, Gilberto De Nucci

“…A total of 817 proteins were generated, and following screening using UniProt “Retrieve/ID Mapping” function and Gene Ontology cellular component category, 124 proteins were identified as membrane proteins. …”
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Control Panel for Transport Vehicle of Technological Purpose with Electric Traction by A. V. Schenyatskiy, R. S. Muzafarov, E. R. Muzafarov, E. S. Chukhlantsev, A. N. Dombrachev

“…Indicating devices, keypad and two function keys are electrically connected to the control unit located inside the box. …”
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