Protective Impacts of <i>Chlorella vulgaris</i> on Cisplatin-Induced Toxicity in Liver, Kidney, and Spleen of Rats: Role of Oxidative Stress, Inflammation, and Nrf2 Modulation by Layla A. Almutairi, Ebtehal G. Abdelghaffar, Hany A. Hafney, Hala M. Ebaid, Sahar A. Alkhodair, Aly A. M. Shaalan, Heba N. Gad EL-Hak

“…Additionally, liver and kidney function markers were markedly impaired, and histopathological analysis revealed structural damage in the liver, kidneys, and spleen. …”
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Cardiac Contractility Modulation as bridge to recovery in a patient with advanced heart failure evaluated for left ventricular assist devices: a case report and review of literatur... by Francesca Menichetti, Marco Solari, Elisa Salvetti, Vincenzo Guarnaccia, Tommaso Girasole, Flavio Venturi, Attilio Del Rosso

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Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways by Yu Zhang, Hailong Lun, Naiqiang Zhu, Naiqiang Zhu, Ning Yang, Kaikai Ding, Bin Chen, Chengbing Chang, Haipeng Gu, Yanqi Liu

“…The aim of this study was to investigate the functions and underlying mechanisms of C1QTNF1-AS1 in the progression of osteosarcoma.MethodsThis investigation focused on elucidating the functional roles and mechanisms of C1QTNF1-AS1 in OS cells. …”
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A 24‐week double‐blind placebo‐controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptom... by Katy Bernard, Sylvie Gouttefangeas, Sylvie Bretin, Stéphanie Galtier, Philippe Robert, Vjera Holthoff‐Detto, Jeffrey Cummings, Maria Pueyo

“…After 24 weeks, no statistically significant treatment difference was demonstrated between S47445 (5, 15 or 50 mg/d) and placebo on cognition (ADAS‐Cog), function (Disability Assessment for Dementia), or depressive symptoms (CSDD). …”
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Comparative effects of xylitol and erythritol on modulating blood glucose; inducing insulin secretion; reducing dyslipidemia and redox imbalance in a type 2 diabetes rat model by Nontokozo Z. Msomi, Ochuko L. Erukainure, Veronica F. Salau, Kolawole A. Olofinsan, Md. Shahidul Islam

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A model of the professional field as the basis for an adaptive educational process by I. I. Shpak, S. N. Kasanin

“…The main purpose of the work is to study the advantages of an activity-based approach, or functional approach in comparison with a subject-based approach, or lecture-based approach for creating a model of a professional field for adaptive educational process. …”
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LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis by Yihan Liu, Yuhua Wang, Long Cui, Runze Li, Dan Xiao, Dan Xiao

“…Mechanistically, OIP5-AS1 functioned as a molecular sponge for miR-429, regulating DOCK4 expression. …”
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Intestinal IL-25 prevents high-fat diet-induced obesity by modulating the cholesterol transporter NPC1L1 expression in the intestinal epithelial cells by Siranart Jeerawattanawart, Pornpimon Angkasekwinai

“…Abstract The intestine is essential for digestion and nutrient absorption, and its altered function contributes to metabolic dysregulation and obesity-induced intestinal inflammation. …”
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Hydrostatic-Pressure Modulation of Band Structure and Elastic Anisotropy in Wurtzite BN, AlN, GaN and InN: A First-Principles DFT Study by Ilyass Ez-zejjari, Haddou El Ghazi, Walid Belaid, Redouane En-nadir, Hassan Abboudi, Ahmed Sali

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Quercetin‐Driven Akkermansia Muciniphila Alleviates Obesity by Modulating Bile Acid Metabolism via an ILA/m6A/CYP8B1 Signaling by Jiaqi Liu, Youhua Liu, Chaoqun Huang, Chuan He, Tongyudan Yang, Ruiti Ren, Zimeng Xin, Xinxia Wang

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Reversible Modulation of Motile Cilia by a Benzo[<i>e</i>][1,2,4]triazinone: A Potential Non-Hormonal Approach to Male Contraception by Maria Chatzifrangkeskou, Alexandra Perdiou, Revekka Kreouzou, Georgia A. Zissimou, Dragos F. Flesariu, Panayiotis A. Koutentis, Paris A. Skourides

“…In this study, we identified 1,3-diphenyl-6-(4-phenylpiperazin-1-yl)benzo[<i>e</i>][1,2,4]triazin-7(1<i>H</i>)-one as a potent and reversible modulator of ciliary function using the <i>Xenopus laevis</i> model. …”
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Astaxanthin mitigates diabetic cardiomyopathy and nephropathy in HF/HFr/STZ diabetic rats via modulating NOX4, fractalkine, Nrf2, and AP-1 pathways by Nesma M.E. Abo El-Nasr, Yosra A. Hussien, Marawan Abd El-Baset, Marwa E. Shabana, Dalia O. Saleh

“…Serum markers of renal and cardiac function, oxidative stress parameters, and electrocardiographic (ECG) measurements were assessed. …”
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Stimulation of corticospinal neurons by optogenetic cAMP inductions promotes motor recovery after spinal cord injury in female rats via raphespinal tract modulation by Beatriz Martínez-Rojas, Samuel Martín-Pérez, Esther Giraldo, Eric Lopez-Mocholi, Ana Alastrue, Yuniesky Andrade-Talavera, Jose Prius-Mengual, Guillem Paniagua, Maria Pedraza, Sonia Hingorani, Benjamin R. Rost, Dietmar Schmitz, Marta Llansola, Vicente Felipo, Antonio Rodríguez-Moreno, Victoria Moreno-Manzano

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Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis by Jiamin Zhao, Ling Kui, Jinqun Huang, Jie Deng, Lingjun Liu, Chenwei Zhu, Yanqiang Shi, Chengyi Li, Yue Xiao, Jinshi Yu, Qing Li, Bin Yang, Bingfeng Leng, Hung Chan

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Crude oligosaccharides extracted from bamboo shoots (Dendrocalamus asper) exhibit prebiotic activity and modulate intestinal morphology in broiler chickens without affecting growth... by Janjira Sittiya, Supawadee Chimtong, Narin Thongwittaya, Koh-en Yamauchi

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Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice by Xiaofeng Wei, Xinhong Cheng, Yang Luo, Xun Li

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Downregulation of OIP5-AS1 inhibits apoptosis in myocardial ischemia/reperfusion injury via modulating the MiR-145-5p/ROCK1 axis. by Jingyan Yang, Jing Liu, Xiaobo Liu, Dongling Xu, Juan Zhang

“…The present study was conducted with the objective of investigating the function of OIP5-AS1 in myocardial I/R injury and exploring its potential mechanisms.…”
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Optical OTFS waveform PAPR analysis for high order modulation employing CNN, DNN, and AE machine learning algorithms under a variety of channel scenarios by Arun Kumar, Nishant Gaur, Aziz Nanthaamornphong

“…Nevertheless, the high peak-to-average power ratio (PAPR) of OTFS modulation severely degrades the system performance, particularly in the case of high-order modulation formats. …”
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UTP14A, DKC1, DDX10, PinX1, and ESF1 Modulate Cardiac Angiogenesis Leading to Obesity-Induced Cardiac Injury by Xiaoyu Pan, Shuchun Chen, Xing Chen, Qingjuan Ren, Lin Yue, Shu Niu, Zelin Li, Ruiyi Zhu, Xiaoyi Chen, Zhuoya Jia, Ruoxi Zhen, Jiangli Ban

“…UTP14A, DKC1, DDX10, PinX1, and ESF1 have been identified as hub genes in obesity-induced pathological changes in the heart and may be involved in obesity-induced cardiac injury by affecting cardiac microcirculatory function.…”
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AP5Z1 affects hepatocellular carcinoma growth and autophagy by regulating PTEN ubiquitination and modulating the PI3K/Akt/mTOR pathway by Zhipeng Quan, Bo Peng, Kai Hu, Lixing Liang, Mingjiang Liu, Lijuan Liao, Shilian Chen, Jing Qin, Songqing He, Zeyuan Li

“…Methods In this study, we examined adaptor-related protein complex 5 subunit ζ1 (AP5Z1) expression in liver cancer and nearby noncancerous tissues to explore its effects on HCC cell growth, death, and autophagy. The functional and molecular mechanisms of AP5Z1 were studied using clinical sample analysis, Western blot (WB), immunohistochemistry (IHC), quantitative reverse-transcription polymerase chain reaction (qRT‒PCR), coimmunoprecipitation (Co-IP), cell proliferation assays, flow cytometry (FCM), autophagy assays, electron microscopy, mass spectrometry (MS), transcriptome analysis, and animal model experiments. …”
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