Modulating Electronic States of Cu in Metal‐Organic Frameworks for Emerging Controllable CH4/C2H4 Selectivity in CO2 Electroreduction by Mingxu Sun, Jiamin Cheng, Akihiko Anzai, Hirokazu Kobayashi, Miho Yamauchi

“…Here, it is reported for the first time the controllable CH4/C2H4 selectivity by modulating the electronic states of Cu incorporated in metal‐organic frameworks with different functional ligands, achieving a Faradaic efficiency of 58% for CH4 on Cu‐incorporated UiO‐66‐H (Ce) composite catalysts, Cu/UiO‐66‐H (Ce) and that of 44% for C2H4 on Cu/UiO‐66‐F (Ce). …”
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A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma. by Sonja Langthaler, Theresa Rienmüller, Susanne Scheruebel, Brigitte Pelzmann, Niroj Shrestha, Klaus Zorn-Pauly, Wolfgang Schreibmayer, Andrew Koff, Christian Baumgartner

“…This hidden Markov-based model represents the electrophysiology behind proliferation of the A549 cell, describing its rhythmic oscillation of the membrane potential able to trigger the transition between cell cycle phases, and it predicts membrane potential changes over the cell cycle provoked by targeted ion channel modulation. This first A549 in-silico cell model opens up a deeper insight and understanding of possible ion channel interactions in tumor development and progression, and is a valuable tool for simulating altered ion channel function in lung cancer electrophysiology.…”
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Modulation of microglia activation and Alzheimer's disease: CX3 chemokine ligand 1/CX3CR and P2X7R signaling by Pavithra Suresh, Sarayut Phasuk, Ingrid Y Liu

“…CX3CL1/CX3CR1 is one important signaling which controls the microglia function. Altering this pathway can have opposite effects on amyloid and tau pathology in AD. …”
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SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1 by Rui Cai, Cong Li, Wenhui Shi, Fenfen Xie, Mengmeng Fan, Hao Zhang, Zhuang Liu, Yuanhua Chen, Qiang Hong

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HES5 Activates Long Noncoding RNA UCA1 to Induce Colorectal Cancer Progression by Modulating miR-185/NOTCH3 Signaling by Mingming Wang, Qinlin Zheng, Zhengfei Zhao, Hong Deng, Qiang Zhang, Hui Yao

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circ-RANGAP1/MicroRNA-542-3p/Myosin Regulatory Light Chain Interacting Protein Axis Modulates the Osteosarcoma Cell Progression by Jundong Sheng, Jin Liu, Junwang Du, Yongping Wang

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“Unraveling EMILIN-1: A Multifunctional ECM Protein with Tumor-Suppressive Roles” Mechanistic Insights into Cancer Protection Through Signaling Modulation and Lymphangiogenesis Con... by Samanta Muzzin, Enrica Timis, Roberto Doliana, Maurizio Mongiat, Paola Spessotto

“…EMILIN-1 (Elastin Microfibril Interface Located Protein 1) is an extracellular matrix homotrimeric glycoprotein belonging to the EMILIN/Multimerin family, with both structural and regulatory roles, increasingly recognized for its tumor-suppressive functions. Initially identified for its involvement in elastogenesis and vascular homeostasis, EMILIN-1 has gradually emerged as a key player in cancer biology. …”
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ON DEFINITION OF BEAMS INHOMOGENEOUS RHEOLOGICAL PROPERTIES by Tatyana A. ANIKINA, Ivan V. BOGACHEV, Alexander O. VATULYAN

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Advances in research on SATB2 and its role in tumor development by Ge Cheng, Chi Tian, Waner Wang, Yangyang Zhou, Xiaoqing Wang, Lei Zhang

“…This review aims to provide a comprehensive summary of the structure, biological functions, and potential role of SATB2 in tumor development. …”
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Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation by Jingchen Shao, Jeonghyeon Kwon, Tianpeng Wang, Stefan Günther, Lukas S. Tombor, Timothy Warwick, Zaib Shaheryar, Ralf P. Brandes, Stefanie Dimmeler, Jan Wenzel, Stefan Offermanns, Markus Schwaninger, Nina Wettschureck

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BiP Proteins from Symbiodiniaceae: A “Shocking” Story by Estefanía Morales-Ruiz, Tania Islas-Flores, Marco A. Villanueva

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Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study by Liang-Yu Huang, Chen-Chen Tan, Wei Xu, Lan Tan, for the Alzheimer’s Disease Neuroimaging Initiative

“…These findings suggest that the interplay between lysosome function and microglia-related neuroinflammation plays key roles in amyloid metabolism.…”
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Acute effects of commercial group exercise classes on arterial stiffness and cardiovagal modulation in healthy young and middle-aged adults: A crossover randomized trial. by Xavier Melo, Adma Lopes, Raquel Coelho, Bruno Simão, Isabel Oliveira, João L Marôco, Sérgio Laranjo, Bo Fernhall, Helena Santa-Clara

“…<h4>Background</h4>Arterial stiffness and cardiac autonomic function are crucial indicators of cardiovascular health. …”
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Zero-voltage and Zero-current-switching of Half-bridge PWM Converter for High Power Applications by Berzan V., Ermurachi Iu.

“…The control of the proposed converter can be implemented by applying the technique of pulse width modulation (PWM). The functionality, stability and performance of the proposed converter topology have been verified on an experimental converter at power range 420 W (400V, 50V).…”
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CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B by Yue-yan Li, Fan-liang Meng, Si-yuan Zhou, Jia-min Du, Wen-jing Li, Qi-yun Liu, Lei Wu, Meng-meng Zhao, Yi Jin, Qun-ye Zhang, Ying Li, Guo-hai Su

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Lactate and Lactylation: Dual Regulators of T-Cell-Mediated Tumor Immunity and Immunotherapy by Zhi-Nan Hao, Xiao-Ping Tan, Qing Zhang, Jie Li, Ruohan Xia, Zhaowu Ma

“…Elevated lactate levels, a hallmark of the Warburg effect, contribute to immune suppression through CD8⁺ T cell functionality and by promoting regulatory T cell (Treg) activity. …”
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DNA‐Nanocrystal Assemblies for Environmentally Responsive and Highly Efficient Energy Harvesting and Storage by Mallikarjuna Reddy Kesama, Sunghwan Kim

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Molecular mechanisms and therapeutic prospects of 4-aminobenzoic acid in neuropsychiatric disorders: a comprehensive review of neurotransmitter modulation, anti-inflammatory pathwa... by Siyu Chen, Yan Su, Weiyan Wu, Yuting Chen, Tiandong Lin, Yangyang Liu

“…4-Aminobenzoic acid (PABA, para-aminobenzoic acid) exhibits multifaceted therapeutic potential in neuropsychiatric disorders through its roles in neurotransmitter modulation, anti-inflammatory action, and antioxidant defense. …”
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Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions by Wu S, Zhou Z, Li Y, Wu R, Jiang J

“…Firmicutes and Enterobacteriaceae influenced the arachidonic acid pathway by modulating 14.15-EET expression levels.Conclusion: MSCsQr-exo facilitate DSW wound healing through modulation of dysbiotic gut microbiota linked to DSW pathology. …”
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Reduced sTWEAK and increased sCD163 levels in HIV-infected patients: modulation by antiretroviral treatment, HIV replication and HCV co-infection. by Luis M Beltrán, Rocío Muñoz Hernández, Rebeca S de Pablo Bernal, José S García Morillo, Jesús Egido, Manuel Leal Noval, Sara Ferrando-Martinez, Luis M Blanco-Colio, Miguel Genebat, José R Villar, Rafael Moreno-Luna, Juan Antonio Moreno

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