Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice by Xinyu Sun, Long Yun, Keming Xie, Renhui Liu, Xinyue Ren, Bokun Zeng, Xudong Cao, Zhi Li, Guihao Zhou, Bang Liu, Luo Peng, Lihong Yuan

“…The intervention also restored gut barrier function by upregulating mucins, goblet cell counts, and tight junction proteins (ZO-1, occludin, and claudin-1) in colonic tissue, along with reducing serum lipopolysaccharide (LPS) levels. …”
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Interspecies signaling modulates the biosynthesis of antimicrobial secondary metabolites related to biological control activities of Pseudomonas fluorescens 2P24 by Nannan Zhang, Xianfeng Zhu, Xuanying Tao, Jie Li, Qi Tang, Xiaochun Liu, Li-Ming Luo, Pingping Zhang, Li-Qun Zhang, Yong-Xing He, Honghua Ge

“…Plant growth-promoting bacterium Pseudomonas produces a spectrum of important antibiotics to inhibit plant pathogens, albeit with an associated metabolic burden. Antibiotics could function as intra- and interspecies signals at subinhibitory concentrations to coordinate gene expression and microbial behaviors. …”
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Long noncoding RNA LINC00339 promotes osteoporosis development via modulating of regulator CDC42 by binding PARP1 by Dong-Li Zhu, Yan Zhang, Xiao-Yu Zhang, Zi-Han Qiu, Ke Li, Xiao-Rong Zhou, Zhen-Zhen He, Xiao-Feng Chen, Shan-Shan Dong, Wen Tian, Ya-Kang Wang, Tie-Lin Yang, Bo Yang, Yan Guo

“…Our previous investigation provided preliminary evidence that single nucleotide polymorphisms (SNPs) may functionally interact with the LINC00339, potentially contributing to the pathogenesis and progression of osteoporosis through undefined molecular pathways. …”
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A Cybernetic Metric Approach to Course Preparation by Russell Jay Hendel

“…The mental processes on which the theory is based are executive function, atomic habit formation, Stroop interference, controllability (attribution) theory, and self-efficacy.…”
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Efficient Neural Network Control of a Brushless DC Motor by A. A. Vеlchеnko, S. A. Pauliukavеts, A. A. Radkеvich, A. K. Ibrahim

“…Based on proactive calculation, a PID controller with self-adjusting parameters using a neural network was built, as well as a block diagram of the PID control system was built on the basis of the BP neural network; also, a speed controller was built using MATLAB modules. Besides, an S-activation function was built as a controller of the BP neural network; the function was based on the mathematical description of the neural network of the control unit of a brushless DC motor. …”
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Orthokeratology for myopia control: a three-year longitudinal study on axial length modulation influenced by baseline age and spherical equivalent by Xiaoxue Hu, Zixun Wang, Boxuan Sun, Xiang Wan, Feng Chang, Weiping Lin, Ruihua Wei

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Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model by Francesca Grilli, Sadman Sakib, Fabio Variola, Shan Zou

“…This study investigates the potential of chemically functionalized nanoscale graphene oxide (GO) as carriers for delivering therapeutic genes in a 3D tumor microenvironment (TME) model, incorporating lung cancer cells, human lung fibroblasts, and macrophages in a Matrigel‐collagen matrix to mimic the structural properties and immune functions. …”
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Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study by Renxian Xie, Renxian Xie, Hongxin Huang, Hongxin Huang, Qingxin Cai, Jiayang Lu, Tong Chen, Tong Chen, Keyan Xie, Jianzhou Chen, Chuangzhen Chen

“…BackgroundRadiotherapy can improve the survival rates of patients with glioma; meanwhile, impaired cognitive functions have been brought to the forefront with the offending organ, the radiosensitive hippocampus. …”
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Temperate Forest Soil Microbiomes and Their Assembly Processes are Modulated by the Interplay of Co‐Existing Tree Species Identity, Diversity and Their Mycorrhizal Type by Hafeez Ul Haq, Bala Singavarapu, Amelie Hauer, Nico Eisenhauer, Olga Ferlian, Helge Bruelheide, Tesfaye Wubet

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Intelligent Algorithm Deep Learning Reinforcement Learning Module Integrated into the Navigation System to Enhance the Ability of Navigation to Accurately Serve Users by Li Jinhao

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<i>circSATB1</i> Modulates Cell Senescence in Age-Related Acute Myeloid Leukemia: A Mechanistic Proposal by Linxiang Han, Xi Wen, Ling Zhang, Xingcheng Yang, Ziyan Wei, Haodong Wu, Yichen Zhan, Huiting Wang, Yu Fang

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BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells by Quan Xiao, Zhe Zhao, Yun Teng, Lungang Wu, Jinlong Wang, Hongjun Xu, Sumei Chen, Quan Zhou

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PSD3, regulated by PKM2, endows growth and metastasis advantages in esophageal squamous cell carcinoma by modulating EMT progression by Qiqi Zhang, Qing Liu, Shutao Zheng, Tao Liu, Lifei Yang, Yiyi Tan, Xiaomei Lu

“…Next, the interaction between PSD3 and PKM2 was examined, and the results showed that PSD3 was directly regulated by PKM2. Functionally, PSD3 was regulated by PKM2 to promote the proliferation, migration and invasion of ESCC cells. …”
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Exploring the role of toxic and therapeutic compounds in aryl hydrocarbon receptor (AhR) modulation: insights from molecular modeling study by Manisha Sahoo, Luna Samanta, Raghunath Satpathy

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Deep Neural Network-Based Detection of Modulated Jamming in Free-Space Optical Systems: Theory and Performance Under Atmospheric Fading by Manav R. Bhatnagar

“…The DNN operates on a composite feature vector comprising raw signal samples, spectral content, energy statistics, and higher-order distributional descriptors, enabling robust detection under both modulated and persistent jamming scenarios. To benchmark the performance of the proposed architecture, we derive a closed-form upper bound on the Bayes classification error using the Bhattacharyya coefficient, expressed analytically in terms of Meijer-G functions. …”
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Modulating the Gut–Muscle Axis: Increasing SCFA-Producing Gut Microbiota Commensals and Decreasing Endotoxin Production to Mitigate Cancer Cachexia by Sagnik Roy, Amir Hossein Alizadeh Bahmani, Mark Davids, Hilde Herrema, Max Nieuwdorp

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Reconfigurable Three-Switch Leg Multi-Port Boost Inverters With Novel Modulation Schemes for Hybrid DC/AC Microgrid Systems by M. Rama Narayana Reddy, B. Dastagiri Reddy, Prajof Prabhakaran, Andrii Chub, Samir Kouro

“…The TSLMPBI topologies are designed to accommodate various configurations, including two DC ports with two AC ports, three DC ports with one AC port, and three DC ports with two AC ports, tailored for different applications. A hybrid modulation scheme was proposed, dynamically adapted to the configuration of DC and AC ports, facilitating seamless boost and dual inversion operations or combined boost, buck, and inversion functionalities within a single converter. …”
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Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat. by Silvia Gazzin, Andrea Lorena Berengeno, Nathalie Strazielle, Francesco Fazzari, Alan Raseni, J Donald Ostrow, Richard Wennberg, Jean-François Ghersi-Egea, Claudio Tiribelli

“…These data suggest that down-regulation of Mrp1 protein at the BSCFB, resulting from a direct effect of UCB on epithelial cells, may impact the Mrp1-mediated neuroprotective functions of the blood-cerebrospinal fluid barrier and actually potentiate UCB neurotoxicity.…”
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Exercise-mediated IL-6 downstream effects modulate brain pathology–can exercise training protocols influence the downstream effects? by Hezhou Li, Anand Thirupathi

“…Additionally, the level of IL-6 determines the nature of molecular signaling that underlies all IL-6-mediated functions. This can be achieved by understanding both classic and IL-6 trans-signaling in different physio-pathological conditions. …”
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Live and heat-killed Leuconostoc mesenteroides counteract the gastrointestinal dysfunction in chronic kidney disease mice through intestinal environment modulation. by Fittree Hayeeawaema, Natthawan Sermwittayawong, Chittipong Tipbunjong, Nawiya Huipao, Paradorn Muangnil, Pissared Khuituan

“…This study aimed to evaluate the probiotic potential of lactic acid bacteria derived from natural sources and to investigate the effects of both live and heat-killed Leuconostoc mesenteroides (Ln.m) on renal and gastrointestinal functions in CKD mice. Ln.m was selected from acid and bile salt intolerance tests, non-hemolytic activity, and antibiotic sensitivity. …”
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