Dimethyl α-ketoglutarate ameliorates cisplatin-induced acute kidney injury by modulating mitophagy through the PINK1/Parkin pathway by Haijing Dou, Huihui Hao, Ruoyi Zhao, Hailun Li, Fangshu Wei, Yong Xu, Donghui Zheng, Juan Xie, Xiang Li

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Small EVs From Adipose‐Derived MSCs Modulate Epidermal Barrier and Inflammation Via Sphingosine‐1‐Phosphate Signaling Pathway by Kyong‐Oh Shin, Jun Ho Lee, Seungwoo Chae, Karin Goto, Hahyun An, Joan S. Wakefield, Dae Hyun Ha, Healim Lee, Kyojin Lee, Hyunju Lee, Ella Shin, Min Ji Kang, Sinhee Lee, Yoshikazu Uchida, Byong Seung Cho, Kyungho Park

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REU-Net: A Remote Sensing Image Building Segmentation Network Based on Residual Structure and the Edge Enhancement Attention Module by Tianen Yuan, Bo Hu

“…Furthermore, a hybrid loss function combining edge consistency loss and binary cross-entropy loss is used to train the network, aiming to improve segmentation accuracy. …”
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Modulation of miR-210 alters phasing of circadian locomotor activity and impairs projections of PDF clock neurons in Drosophila melanogaster. by Paola Cusumano, Alberto Biscontin, Federica Sandrelli, Gabriella M Mazzotta, Claudia Tregnago, Cristiano De Pittà, Rodolfo Costa

“…We investigated the function of Drosophila miR-210 in circadian behaviour by misexpressing it within circadian clock cells. …”
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Growth-inhibiting effects of the unconventional plant APYRASE 7 of Arabidopsis thaliana influences the LRX/RALF/FER growth regulatory module. by Shibu Gupta, Amandine Guérin, Aline Herger, Xiaoyu Hou, Myriam Schaufelberger, Romain Roulard, Anouck Diet, Stefan Roffler, Valérie Lefebvre, Thomas Wicker, Jérôme Pelloux, Christoph Ringli

“…Together, this study reveals a function of APY7 in cell wall formation and cell growth that is connected to growth processes influenced by the LRX/RALF/FER signaling module.…”
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Protaetia brevitarsis larvae extract ameliorated obesity in high fat diet-fed mice by modulating gut microbiota and lipid metabolism by Zongqi Zhang, Sicong Chen, Qinglei Wang, Chunqin Liu, Jinhua Xiao, Dawei Huang

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Gut Microbiome-Host Genetics Co-Evolution Shapes Adiposity by Modulating Energy and Lipid Metabolism in Selectively Bred Broiler Chickens by Guangqi Gao, Yangbo Jiao, Lai-Yu Kwok, Zhi Zhong

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Water temperature modulates multidimensional plastic responses to water flow during the ontogeny of a neotropical fish (Astyanax lacustris, characiformes) by Leandro Lofeu, Bianca Bonini-Campos, Tiana Kohlsdorf

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Analysis of Power Enhancement in Facade-BIPV Systems Through Module-Level Power Optimizer: Evaluating Performance Under Shading Conditions by Jiyoung Eum, Hyun-Jung Choi

“…This confirms the optimizer function in enabling shaded and non-shaded modules to operate independently at maximum power. …”
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Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

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Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study by Isabelle C. Jeusette, Emmanuelle Apper, Marina L. Meli, Regina Hofmann-Lehmann, Anna Salas-Mani, Anna Fernández-Pinteño, Olga Francino, Celina Torre

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Comprehensive single-cell pan-cancer atlas unveils IFI30+ macrophages as key modulators of intra-tumoral immune dynamics by Lihe Jiang, Lihe Jiang, Lihe Jiang, Peili Wang, Peili Wang, Yixuan Hou, Jingying Chen, Hua Li, Hua Li

“…Substantiated by single-cell analysis, IFI30 exhibits significant functional enrichment in immune-related pathways. Co-expression with immune-related genes, including MHC elements and immune checkpoints, further validates its relevance.ConclusionOur study positions IFI30 as a promising immunotherapeutic target. …”
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Calcium-binding site in AA10 LPMO from Vibrio cholerae suggests modulating effects during environmental survival and infection by Mateu Montserrat-Canals, Kaare Bjerregaard-Andersen, Henrik Vinther Sørensen, Eirik Kommedal, Gabriele Cordara, Gustav Vaaje-Kolstad, Ute Krengel

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Investigation of Terminalia arjuna as potential IL-4 and IL-13 modulator for the prevention of autoimmune diabetes: A Pharmacoinformatics-based study by Aziz Unnisa, Saheem Ahmad, Suresh Babu Jandrajupalli, Kareem M. Younes, Sally Hassan Abobaker, Swarnalatha Chandolu, Mohammad Khalid, Lakshmi Sudeepthi N

“… Cytokines are proteins that play a critical role in the development, maturation, and functional activities of immune cells. For the first time, we have investigated the potential role of Terminalia arjuna as IL-4 and IL-13 modulators for preventing T1DM, i.e., autoimmune diabetes. …”
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SPOCK1 promotes the progression of breast cancer by modulating cancer-associated fibroblasts and exerts a synergistic effect with ANXA2 by Yuan Jie, Xin Fei, Meng Fan

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Human embryonic stem cell-derived Sertoli cells as an immune modulator of cell transplantation therapy in a diabetic mice model by Jeoung Eun Lee, Chang Woo Lee, A-Reum Han, Jina Kim, Dong Ryul Lee

“…Materials and methods We established a protocol for mass production of SCs from human ESCs (hESC-SCs) and their functional properties were analyzed in vitro and in diabetic-induced mice after their co-transplantation with human insulin-secreting cells. …”
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Exploring the hepatic-ophthalmic axis through immune modulation and cellular dynamics in diabetic retinopathy and non-alcoholic fatty liver disease by Shuyan Zhang, Jiajun Wu, Leilei Wang, Cheng Zhang, Yinjian Zhang, Yibin Feng

“…Additionally, gene set enrichment and variation analyses (GSEA and GSVA) were performed to uncover key functional enrichments. Results Our comparative analysis of the two datasets focused on T cells, macrophages and endothelial cells, revealing SYNE2 as a notable DEG. …”
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ZFAS1/STAT3 axis modulates imatinib resistance of chronic myeloid leukemia cells through glucose metabolism reprogramming by Lan Yang, Yanqiu Han

“…However, imatinib resistance remains a major therapeutic challenge.ObjectiveThis study aims to elucidate the role of the ZFAS1/STAT3 signaling axis in mediating imatinib resistance in CML by promoting metabolic reprogramming, with a particular focus on alterations in glucose metabolism.MethodsImatinib-resistant (IM-R) K562 cells were used to investigate the functional role of ZFAS1gene. Following ZFAS1 knockdown, assessments of cell viability, apoptosis, and glucose metabolism were performed. …”
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First-Principles Study on the Modulation of Schottky Barrier in Graphene/Janus MoSSe Heterojunctions by Interface Contact and Electric Field Effects by Zhe Zhang, Jiahui Li, Xiaopei Xu, Guodong Shi

“…Due to the difference in atomic electronegativity and surface work function (WF), the Gr/JSMoSe heterojunction formed by the contact of S atoms with Gr exhibits an n-type Schottky barrier, whereas the Gr/JSeMoS heterojunction formed by the contact of the Se atoms with Gr reveals a p-type Schottky barrier. …”
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Celastrol modulates damage of renal tissues in Immunoglobulin A nephropathy via targeting TGase-2/HMGB1 signaling pathway by Yanping Wu, Ruman Chen, Danfang Deng, Wenjing Wu, Xiaoqin Wang

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