Modular assembled biomimetic nanobubbles for synergistic therapy of ischemic stroke via cascade modulation thrombo-inflammatory network by Mingxi Li, Xuan Xu, Guoyan Tang, Huan Wu, Yakun Wang, Chen Cheng, Hongde Liu, Fang Yang

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Ciprofloxacin Exerts Anti-Tumor Effects In Vivo Through cGAS-STING Activation and Modulates Tumor Microenvironment by Jian-Syun Chen, Chih-Wen Chi, Cheng-Ta Lai, Shu-Hua Wu, Hui-Ru Shieh, Jiin-Cherng Yen, Yu-Jen Chen

“…Immunotherapy targeting the immune functions of the tumor microenvironment (TME) is beneficial for colorectal cancer; however, the response rate is poor. …”
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Realizing Sunlight‐Induced Efficiently Dynamic Infrared Emissivity Modulation Based on Aluminum‐Doped zinc Oxide Nanocrystals by Yan Jia, Dongqing Liu, Desui Chen, Yizheng Jin, Yufei Ge, Wenxia Zhang, Chen Chen, Baizhang Cheng, Xinfei Wang, Tianwen Liu, Mingyang Li, Mei Zu, Zi Wang, Haifeng Cheng

“…A straightforward device architecture that integrates an AZO nanocrystal film with an infrared reflective layer and a substrate, functioning as a photo‐induced dynamic infrared emissivity modulator, which can be triggered by weak ultraviolet light in sunlight, is engineered. …”
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Quarter-Wave Plate Meta-Atom Metasurfaces for Continuous Longitudinal Polarization Modulation of Hybrid Poincaré Sphere Beams by Yunxiao Li, Quanhong Feng, Gongzheng Fang, Haonan Sun, Xingyi Fan, Zhenghao Liu, Hao Wang, Yuexu Si, Shuhao Si, Xuran Li, Chen Cheng

“…This work offers new insights into the generation and control of HyOPS light fields and contributes significantly to the development of miniaturized, functionally integrated high-performance nanophotonics.…”
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Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH by Tobias Obermann, Teri Sakshaug, Vishnu Vignesh Kanagaraj, Andreas Abentung, Mirta Mittelstedt Leal de Sousa, Lars Hagen, Antonio Sarno, Magnar Bjørås, Katja Scheffler

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Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. by Philip M Elks, Sabrina Brizee, Michiel van der Vaart, Sarah R Walmsley, Fredericus J van Eeden, Stephen A Renshaw, Annemarie H Meijer

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Module Partition of Mechatronic Products Based on Core Part Hierarchical Clustering and Non-Core Part Association Analysis by Shuai Wang, Yi-Fei Song, Guang-Yu Zou, Jia-Xiang Man

“…Production using modular architecture can not only shorten the product development cycle and improve the efficiency of product development, but also facilitate the upgrading of a product’s main functions and the recycling of materials. However, mechatronic products are plagued by various problems, such as greater difficulty in development and longer product development cycles due to their large numbers of parts with intricate internal relationships. …”
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BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING by Shijie Yao, Siming Chen, Anjin Wang, Ziyan Liang, Xuelian Liu, Yang Gao, Hongbing Cai

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Fumarate and nitrate reduction regulator (FNR) modulates hypermucoviscosity and virulence in hypervirulent Klebsiella pneumoniae through anaerobic adaptation by Yidan Xu, Ruolan Guo, Ruomei Wang, Zhe Su, Yulu Wu, Chengbin Xie, Pinjia Wang

“…This study demonstrates that FNR modulates the HMV phenotype and virulence of the hvKP strain NTUH-K2044 under anaerobic conditions. …”
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Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma Via STING signaling by Zongjuan Li, Yang Zhang, Weifeng Hong, Biao Wang, Yixing Chen, Ping Yang, Jian Zhou, Jia Fan, Zhaochong Zeng, Shisuo Du

“…Mechanistically, gut microbiome dysbiosis impairs antitumor immune responses by suppressing antigen presentation and inhibiting effector T cell functions through the cGAS–STING–IFN-I pathway. Cyclic-di-AMP – an emerging second messenger of bacteria – may act as a STING agonist and is thus a potential target for the prediction and modulation of responses to RT in HCC patients. …”
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Injectable platelet-mimicking silk protein-peptide conjugate microspheres for hemostasis modulation and targeted treatment of internal bleeding by Yajun Shuai, Yu Qian, Meidan Zheng, Chi Yan, Jue Wang, Peng Wang, Jie Wang, Chuanbin Mao, Mingying Yang

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A Single Session of tDCS Stimulation Can Modulate an EEG Microstate Associated With Anxiety in Patients With Depression by Keiichiro Nishida, Shota Minami, Tomonari Yamane, Satsuki Ueda, Banri Tsukuda, Shunichiro Ikeda, Daisuke Haruna, Masafumi Yoshimura, Tetsufumi Kanazawa, Thomas Koenig

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Fluridone promotes the germination of Polygonatum cyrtonema seeds by modulating hormone signal transduction, phenylpropanoid biosynthesis, and energy metabolism by Xiaogang Jiang, Darong Li, Hua Wang, Yuying Yang, Kaidi Yu, Jinwen You, Haihua Liu, Xiaoliang Guo, Yinsheng He, Wuxian Zhou, Qingfang Wang

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Astaxanthin Mitigates ADHD Symptoms in Spontaneously Hypertensive Rats via Dopaminergic Modulation and Brain–Gut Axis Regulation by Yueyang Leng, Ning Wu, Jing Wang, Lihua Geng, Yang Yue, Quanbin Zhang

“…Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder that significantly impacts learning, daily functioning, and personal development. Astaxanthin (ASTA), a naturally occurring antioxidant, has garnered interest as a potential therapeutic agent for various diseases, particularly in mitigating oxidative stress. …”
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mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors by Li Yan, Nina Bhardwaj, Tibor Keler, Kunle Odunsi, Song Liu, Junko Matsuzaki, Takemasa Tsuji, Mark Long, Thinle Chodon, Emese Zsiros, Protul Shrikant, Jianming Wang, Alan Hutson, Stephanie Blank, Amit Lugade, Richard Koya, Spencer R Rosario, Henry G Withers, Shashikant B Lele

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Exogenous prostaglandin D2 as a modulator in bovine endometritis: implications for reducing antibiotic use in dairy cattle by Xiaolin Yang, Xiaolin Yang, Shuangyi Zhang, Shuangyi Zhang, Bo Liu, Bo Liu, Lili Guo, Lili Guo, Pengfei Gong, Pengfei Gong, Pengfei Gong, Jingze Wu, Jingze Wu, Yi Zhao, Yi Zhao, Wei Mao, Wei Mao, Jinshan Cao, Jinshan Cao

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Quercetin modulates transcription of the apoptotic and CatSper genes and optimises post thaw viability and kinematics of buck spermatozoa by Alok Kumar, J. K. Prasad, Nishant Kumar, Sonika Verma, Mukul Anand, Amrita Behera, Ajeet Kumar, Jitendra Tiwari, Rahul Dhariya, Sumit Singhal, Vishal Yadav

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A Unified Framework for Fault and Performance Prediction Using Spatio-Temporal Geometric Features Based on STSFE by Dong-Hyun Kang, A-Youn Yang, Jong-Min Lee, Jong-Gu Lee

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Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions by Yuan Gao, Yanyan Liu, Tingting Ma, Qimeng Liang, Junqi Sun, Xiaomeng Wu, Yinglong Song, Hui Nie, Jun Huang, Guangqing Mu

“…Dairy products—encompassing yogurt, kefir, cheese, and cultured milk beverages—are emerging as versatile, food-based modulators of gut microbiota and host physiology. This review synthesizes mechanistic insights demonstrating how live starter cultures and their fermentation-derived metabolites (short-chain fatty acids, bioactive peptides, and exopolysaccharides) act synergistically to enhance microbial diversity, reinforce epithelial barrier integrity via upregulation of tight-junction proteins, and modulate immune signaling. …”
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WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification by Dawei Yan, Lei Wan, Lei Wan, Lei Wan

“…WTAP expression was modulated via transfection (overexpression or knockdown), and m⁶A modification levels were analyzed using MeRIP-qPCR. …”
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