The role of cocoa flavanols in modulating peripheral and cerebral microvascular function in healthy individuals and populations at-risk of cardiovascular disease: a systematic review by Sophie Richardson, Janice Marshall, Catarina Rendeiro

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Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation by Gee Euhn Choi, Ji Yong Park, Mo Ran Park, Chang Woo Chae, Young Hyun Jung, Jae Ryong Lim, Jee Hyeon Yoon, Ji Hyeon Cho, Ho Jae Han

“…Similarly, prenatal corticosterone exposure led to impaired neuropsychiatric and cognitive function in the offspring by affecting mitochondrial distribution and synaptogenesis, rescued by Miro1WT, but not N-terminal GTPase active form Miro1P26V, expression. …”
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Diabetes-associated sleep fragmentation impairs liver and heart function via SIRT1-dependent epigenetic modulation of NADPH oxidase 4 by Yuanfang Guo, Jie Wang, Dongmei Zhang, Yufeng Tang, Quanli Cheng, Jiahao Li, Ting Gao, Xiaohui Zhang, Guangping Lu, Mingrui Liu, Xun Guan, Xinyu Tang, Junlian Gu

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Spade Leaf Extract Phytosome Modulates Krox-20, Neuregulinـ1, Phospholipids, and Cognitive Function of Traumatic Brain Injury Model in Rats by Alif Fariz Jazmi, Putri Fitri Alfiantya, Sitti Ayu Hemas Nurarifah, Erlin Aditia Purmitasari, Lilin Andreas Vitania, Wibi Riawan

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Optical band gap modulation in functionalized chitosan biopolymer hybrids using absorption and derivative spectrum fitting methods: A spectroscopic analysis by Dyari M. Mamand, Dana S. Muhammad, Daron Q. Muheddin, Karzan A. Abdalkarim, Dana A. Tahir, Hawkar A. Muhammad, Shujahadeen B. Aziz, Sarkawt A. Hussen, Jamal Hassan

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PEDF-Expressing mesenchymal stem cells restore ovarian function via Tim-3-Mediated immune modulation in primary ovarian failure by Seyida Yimamuyushan, Song Shi, Aikeremujiang Muheremu, Jinling Yi

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The STAT3-VDAC1 axis modulates mitochondrial function and plays a critical role in the survival of acute myeloid leukemia cells by Kellen B. Gil, Jamie Borg, Rosana Moreira Pereira, Anagha Inguva-Sheth, Geovana Araujo, Jeremy Rahkola, William Showers, Abby Grier, Angelo D’Alessandro, Clayton Smith, Christine McMahon, Daniel A. Pollyea, Austin E. Gillen, Maria L. Amaya

“…We discovered a novel interaction of STAT3 with voltage-dependent anion channel 1 (VDAC1) in the mitochondria which provides a mechanism through which STAT3 modulates mitochondrial function and cell survival. …”
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Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding in vitro and links PrP function and dysfunction. by James F Graham, Dominic Kurian, Sonya Agarwal, Lorna Toovey, Lawrence Hunt, Louise Kirby, Teresa J T Pinheiro, Steven J Banner, Andrew C Gill

“…Consistent with previous results, the same protein inhibited fibrillisation kinetics of recombinant PrP. Since functional interactions between PrP(C) and Na(+)/K(+)-ATPase have previously been reported in astrocytes, our data highlight this molecule as a key link between PrP function, dysfunction and misfolding.…”
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Module M1 of zebrafish neuroglobin acts as a structural and functional protein building block for a cell-membrane-penetrating activity. by Seiji Watanabe, Keisuke Wakasugi

“…These results enable us to conclude that such module substitutions will facilitate the design and production of novel functional proteins.…”
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Comparative effects of renin-angiotensin-aldosterone system modulators on right heart function and prognosis in patients with severe systolic chronic heart failure by K. G. Adamyan, L. R. Tumasyan, A. L. Chilingaryan

“…To compare the effects of renin-angiotensin-aldosterone system (RAAS) modulators in patients with severe chronic heart failure (CHF). …”
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THE STUDY OF CELL VALUES DISTRIBUTION LAWS IN THE STATIC RAM CHIPS USED AS A PHYSICALLY UNCLONABLE FUNCTION IN A MUTUAL AUTHENTICATION MODULE by G. S. Aliev, O. V. Malsugenov, O. S. Mezentseva

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Emerging therapeutic strategies: The potential of caffeic acid-vanadium nanozymes in modulating macrophage function and reducing skin flap ischemia–reperfusion injury by Jintao Fu, Huile Gao

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Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination by Melanie Lohrberg, Lena Sünke Mortensen, Carolina Thomas, Franziska Fries, Franziska van der Meer, Alexander Götz, Carolin Landt, Hong Jun Rhee, JeongSeop Rhee, David Gómez-Varela, Manuela Schmidt, Wiebke Möbius, Torben Ruhwedel, Luis A. Pardo, Linus Remling, Nadine Kramann, Claudia Wrzos, Erik Bahn, Christine Stadelmann, Alonso Barrantes-Freer

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Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function by Tao Li, Wei Li, Cheng Zheng, Jannette M. Dufour, William H. Walker, Shuiqiao Yuan, Zhibing Zhang

“…Since SPAG6L decorates microtubules and modulates cytoskeleton function, and Sertoli cells have a well-developed microtubule transport network, the potential function of SPAG6L in Sertoli cells was evaluated. …”
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Teosinte-derived SynCom and precision biofertilization modulate the maize microbiome, enhancing growth, yield, and soil functionality in a Mexican field by Juan Alfredo Hernández-García, Julio S. Bernal, Sanjay Antony-Babu, Lourdes Villa-Tanaca, César Hernández-Rodríguez, Esaú De-la-Vega-Camarillo, Esaú De-la-Vega-Camarillo, Esaú De-la-Vega-Camarillo

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Crohn’s Disease-associated variant in laccase domain containing 1 (LACC1) modulates T cell gene expression, metabolism and T cell function by Yingcong Li, Gabriel Ascui, Martina Dicker, Thomas Riffelmacher, Vivek Chandra, Benjamin Schmiedel, Ting-Fang Chou, Pandurangan Vijayanand, Mitchell Kronenberg

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Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters by Kit-Leong Cheong, Amanullah Sabir, Suresh Veeraperumal, Franck Quero, Rui Li, Qiaoli Zhao, Karsoon Tan, Saiyi Zhong, Udayakumar Veerabagu

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Bovine colostrum-derived extracellular vesicles protect against non-alcoholic steatohepatitis by modulating gut microbiota and enhancing gut barrier function by Daye Mun, Sangdon Ryu, Daniel Junpyo Lee, Min-Jin Kwak, Hyejin Choi, An Na Kang, Dong-Hyun Lim, Sangnam Oh, Younghoon Kim

“…Recent studies have highlighted the therapeutic potential of bovine colostrum-derived extracellular vesicles (BCEVs) in modulating gut microbiota and enhancing gut barrier function, but their effects on NASH remain largely unexplored. …”
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Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway by Yoshitaka Adachi, Seitaro Terakura, Masahide Osaki, Yusuke Okuno, Yoshitaka Sato, Ken Sagou, Yuki Takeuchi, Hirofumi Yokota, Kanae Imai, Peter Steinberger, Judith Leitner, Ryo Hanajiri, Makoto Murata, Hitoshi Kiyoi

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Clostridium butyricum enhances cognitive function in APP/PS1 mice by modulating neuropathology and regulating acetic acid levels in the gut microbiota by Ye Shiqing, Lu Xinjie, Zhu Xiaotong, Chen Jiayan, Lu Jiahai, Chen Xiaodong, Lou Yongliang, Li Xiang

“…In APP/PS1 mice, CBM588 improved cognitive function and alleviated colonic tissue pathology by modulating tight junction proteins (upregulating Claudin 1, ZO-1, and Occludin) and reducing inflammatory cytokines (IL-6, IL-1β, and TNF-α mRNA). …”
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