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The therapeutic success of approaches to the gastrointestinal microbiome modulation in the treatment of obesity, metabolic syndrome and type 2 diabetes mellitus
Published 2025-01-01“…In this regard, attempts are made to modulate the composition and functional activity of the microbiota as a primary or adjuvant way of treating various disorders. …”
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A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.
Published 2012-09-01“…However, functions for any of the plasmodial protein phosphatases are unknown. …”
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3267
Defeating angle tracking: A comprehensive analysis of scan rate modulation jamming against sequential lobing radars
Published 2024-11-01“…Furthermore, the optimal duty cycle as a function of JSR, which maximises break‐lock probability is presented. …”
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3268
Electrical modulation of the sympathetic nervous system in order to augment cerebral blood flow: a protocol for an experimental study
“…Autoregulation is evaluated with transfer function analysis and autoregulatory index calculations.Ethics and dissemination Ethical registration was granted by Medical Review Ethics Committee Groningen (ID METc 2010.123). …”
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Synergistic modulation of gut microbiota and mindfulness-based interventions in schizophrenia: Integrating neurotransmitter regulation and multimodal therapeutic strategies
Published 2025-05-01“…In parallel, MBIs, including Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT), promote improvements in emotional regulation, cognitive function, and neuroplasticity through the modulation of neurophysiological pathways, notably by attenuating amygdala reactivity and heightening prefrontal cortex engagement. …”
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Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation
Published 2025-02-01“…Abstract This study investigates the role of Gum Arabic Mannose Oligosaccharides (GA-MOS) in modulating gut microbiota and alleviating symptoms of Inflammatory Bowel Disease (IBD). …”
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Bovine colostrum-derived exosomes alleviate muscle degeneration by modulating gut microbiota and metabolic homeostasis in atrophy models
Published 2025-07-01“…This study aimed to evaluate the potential functional role of bovine colostrum-derived exosomes (BCE) in reducing muscle atrophy. …”
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Very-Large-Scale Integration-Friendly Method for Vital Activity Detection with Frequency-Modulated Continuous Wave Radars
Published 2025-03-01“…A simple algorithm for respiratory activity detection in data produced by Frequency-Modulated Continuous-Wave (FMCW) radars is presented in this paper. …”
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THE FREQUENCY AND FITNESS OF m6A-ASSOCIATED VARIANTS COULD BE MODULATED BY THE THERMODYNAMIC STABILITY OF AN OVERLAPPING G-QUADRUPLEX
Published 2023-10-01“…Their synergy also has functional consequences. Since m6A is known to be enzymatically created in the DRACH-motif, and that genetic variants can create a novel DRACH-motif or abolish a pre-existing DRACH-motif, we can hypothesize that variants which affect the gene product level through modulating m6A-G4 colocalization, may also consequently affect fitness and change the allele frequency. …”
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Optimizing the Shape of Signals with Quadrature Amplitude Modulation According to the Criterion of Given Reduction Rate of Out-of-Band Emissions
Published 2022-09-01“…When searching for optimal signals, the mathematical apparatus of communication theory and functional analysis, as well as the methods of calculus of variations, were used. …”
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Observation of Orbital-Selective Dual Modulations in an Anisotropic Antiferromagnetic Kagome Metal TbTi_{3}Bi_{4}
Published 2025-07-01“…By combining soft x-ray and vacuum ultraviolet angle-resolved photoemission spectroscopy measurements, neutron powder diffraction, scanning tunneling microscopy, and density-functional-theory calculations, we identify these dual-band reconstructions as manifestations of the AFM order driven by a (approximately 1/3, 0.28, 0) nesting instability of the intercalated Tb 5d_{xz} orbitals. …”
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Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes.
Published 2010-10-01“…Based on studies using the purified compound, PGL-1 was proposed to mediate the tropism of M. leprae for the nervous system and to modulate host immune responses. However, deciphering the biological function of this glycolipid has been hampered by the inability to grow M. leprae in vitro and to genetically engineer this bacterium. …”
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