Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling by Dianaly T. Au, Mary Migliorini, Dudley K. Strickland, Selen C. Muratoglu

“…Finally, circulating levels of sFRP-5, a potent anti-inflammatory adipokine that functions as a decoy receptor for Wnt5a, were elevated in LDLR−/−; macLRP1−/− mice. …”
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Comparative Analysis of Modulation Strategies for Indirect Matrix Converter Based on RMS Value of Common-mode Voltage by HUANG Linfeng, BAI Huan, YOU Shuai, WEN Liang, ZHANG Cheng, ZHANG Yanlei

“…However, these converters inevitably generate common-mode voltages during modulation operations, causing motor damage and affecting the reliable functioning of the systems. …”
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Dietary supplementation with L-citrulline improves amino acid composition and broiler performance, and modulates gut microbiota by Yan Ma, Tingting Liu, Shuaihu Chen, Hong Shen, Jungang Wang

“…This indicates that L-Cit can enhance the production performance of broilers, and improve antioxidant activity and immune functions, thereby protecting intestinal health. The optimum dietary amount of L-Cit is 1 to 1.5%.…”
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Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation by Sarvatit Patel, Kai Ellis, Kai Ellis, Corey A. Scipione, Jason E. Fish, Jason E. Fish, Jason E. Fish, Jason E. Fish, Kathryn L. Howe, Kathryn L. Howe, Kathryn L. Howe, Kathryn L. Howe, Kathryn L. Howe

“…This study determined how senescent ECs communicate with monocytes, whether extracellular vesicles (EVs) released from senescent ECs affect monocyte functions, and investigated the potential for epigallocatechin-3-gallate (EGCG), a flavonoid in green tea, to reverse these effects. …”
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Design and synthesis of a novel quinoline thiazolidinedione hybrid as a potential antidiabetic PPARγ modulator by Ayman M. Ibrahim, Mai E. Shoman, Radwa Taher Mohie el-dien, Entesar Ali Saber, Mahmoud Abdelnaser, Sherif A. Maher, Alaa M. Hayallah, Mahmoud Abdul-Aziz El-Rehany, Gamal El-Din A. Abuo-Rahma

“…Herein, we report the design and synthesis of (Z)-5-benzylidene-3-((2-chloroquinolin-3-yl)methyl)thiazolidine-2,4-dione (compound 7), a novel TZD derivative that functions as a potential PPARγ modulator. Compound 7 reduced blood glucose level (BGL) by 22.33% after 15 days of treatment with a daily single oral dose, demonstrating an antidiabetic effect comparable to TZDs. …”
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MicroRNA-150 Modulates Adipogenic Differentiation of Adipose-Derived Stem Cells by Targeting Notch3 by Xiang Li, Yu Zhao, Xiuquan Li, Qiao Wang, Qiang Ao, Xiaohong Wang, Xiaohong Tian, Hao Tong, Deyu Kong, Shijie Chang, Shuling Bai, Jun Fan

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Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways by Xuhui Yuan, Jiayu Li, Bo Yu, Feng Cai, Binqi Chen, Jun Liu, Yuanxiang Peng, Duo Zeng, Qi Liao, Lang Liu

“…Methods: OS cell lines (MG63 and 143B) were exposed to varying concentrations of DEM, followed by assessment of diverse cell functions. RNA sequencing was implemented to identify the molecular pathways affected by DEM exposure. …”
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Nutrient availability modulates the effects of plastic leachates on the growth and community dynamics of free-living freshwater bacteria by Marius Schubert, Fazel Abdolahpur Monikh, Fazel Abdolahpur Monikh, Fazel Abdolahpur Monikh, Yuyi Yang, Yuyi Yang, Yuyi Yang, Hans-Peter Grossart, Hans-Peter Grossart

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Microplastics, invasive species and fungal stressors modulate antioxidative mechanisms, rhizosphere enzymes and microbial dynamics in alfalfa by Muhammad Anas, Muhammad Riaz, Meng-Ting Yan, Yi-Fan Liu, Ying Li, Shan- Shan Qi, Zhi-Cong Dai, Dao-Lin Du

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Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

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PENGEMBANGAN E-MODUL INTERAKTIF UNTUK MENDUKUNG ALGEBRAIC THINKING PADA MATERI TURUNAN FUNGSI ALJABAR by Sri Winarni, Rony Pargaulan Simanjuntak, Marlina Marlina, Rohati Rohati, Ade Kumalasari

“…The aim of this research is to produce and test interactive e-modules to support algebraic thinking on material derived from algebraic functions using the ADDIE model which is valid, practical and effective. …”
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HCAR2 Exerts Anti-Depressive Effects on Corticosterone-Induced Depression in Mice by Modulating Microglial Activity by Zhao Pan, Li Jiang, Jiacheng Chen, Sicong Xu, Ping Zhang, Yili Yi, Yangzhi Xie, Yongjun Chen

“…Hydroxy-carboxylic acid receptor 2 (HCAR2) functions as a receptor for various diet-derived metabolites. …”
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Study of the analog response of the silicon tracking system sensors of the CBM experiment using the LTspice package by O. O. Kshyvanskyi, V. M. Pugatch, M. A. Teklishyn

“…A method for simulating the functioning of analog electronics of detector modules based on double-sided microstrip silicon sensors of the Silicon Tracking System (STS) of the CBM experiment has been developed. …”
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Distinct potency of compounds targeting the T1R3 subunit in modulating the response of human sweet and umami taste receptors by Maiko Kawasaki, Yuta Kidera, Ryusei Goda, Chiaki Taketani, Misato Ide, Wataru Fujii, Tomoya Nakagita, Takumi Misaka

“…The difference in the heterodimeric partners to T1R3 may account for their distinct modulation patterns of receptor function.…”
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A Multi-Step Topological Optimization Approach for Spacer Shape Design in Double-Sided SiC MOSFET Power Modules Considering Thermo-Mechanical Effects by Yuhang Guo, Ke Chen, Wentao Jiang, Longnv Li, Gaojia Zhu

“…Following this, TO with the selected target function is performed on 3D simplified models featuring diverse spacer combination architectures, with the preferable one chosen based on the outcomes. …”
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Modulating Osteoclast Activity and Immune Responses with Ultra-Low-Dose Silver Nanoparticle-Loaded TiO₂ Nanotubes for Osteoporotic Bone Regeneration by Zhen Wang, Penghui Xiang, Zhe Xu, Meiqi Gu, Rui Zhang, Yifei Li, Fei Xin, Chengla Yi

“…In vitro assays focused on evaluating cell viability and osteoclast function, while in vivo assessments employed osteoporotic rat models to monitor bone healing via histological examination and micro-computed tomography (micro-CT) imaging. …”
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Porous Silicon & Titanium Dioxide Coatings Prepared by Atmospheric Pressure Plasma Jet Chemical Vapour Deposition Technique-A Novel Coating Technology for Photovoltaic Modules by S. Bhatt, J. Pulpytel, F. Krcma, V. Mazankova, F. Arefi-Khonsari

“…The FTIR and SEM analyses were better used to monitor the chemical composition and the morphology of the films in function of the different experimental conditions.…”
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Unlocking microbiota potential: the role of organic copper in enhancing healthy white shrimp (Penaeus vannamei) farming by Jinzhu Yang, Xiaoyang Yao, Zhonghao Zhang, Gang Lin, Mingzhu Li, Kangsen Mai, Yanjiao Zhang

“…Taxa associated with nutrient metabolism, including Butyricicoccus, Lactobacillus, and genera in the family Lachnospiraceae, Prevotellaceae, Rikenellaceae and Ruminococcaceae, were significantly enriched, correlating well with improved nutritional profiles. In accordance, functional annotation revealed that the organic copper group exhibited higher abundances of functional modules associated with nutrient and energy metabolism such as carbon and nitrogen cycling. …”
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The effect of binaural pulse modulation (B.P.M) on brain state in depression and anxiety: a case series by Gerry Leisman, Joseph Wallach, Yanin Machado-Ferrer, Mauricio Chinchilla-Acosta, Abraham Gérard Meyer, Robert Lebovits, Scott Donkin

“…Abstract Objective In this pilot study a binaural pulse modulator was tested to see if it leads to a change in self-reported measures of distress. …”
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Autonomic modulation at rest and in response to postural change in adolescents with Duchenne muscular dystrophy: a cross-sectional study by Mariana Viana Rodrigues, Mileide Cristina Stoco-Oliveira, Talita Dias da Silva, Celso Ferreira, Heloisa Balotari Valente, Laís Manata Vanzella, Luiz Carlos Marques Vanderlei

“…Participants’ weight and height were assessed. Lower limb function, motor limitations and functional abilities of the participants in the DMD group were classified using the Vignos scale, Egen classification and motor function measurement, respectively. …”
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