Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes. by Anthony Aylward, Mei-Lin Okino, Paola Benaglio, Joshua Chiou, Elisha Beebe, Jose Andres Padilla, Sharlene Diep, Kyle J Gaulton

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Kidins220/ARMS is a novel modulator of short-term synaptic plasticity in hippocampal GABAergic neurons. by Joachim Scholz-Starke, Fabrizia Cesca, Giampietro Schiavo, Fabio Benfenati, Pietro Baldelli

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Effects of taurine, brimonidine and betaxolol on oscillation modulation and stimulation efficiency in degenerated rd10 mouse retinas by Kim Schaffrath, Claudia Ingensiep, Frank Müller, Peter Walter, Sandra Johnen

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Experimental Optimization of the Energy Characteristics of a Ground Penetrating Radar with Continuous Linear-Frequency-Modulated Radiation by I. Yu. Malevich, A. S. Lopatchenko

“…The responses of the system to an increase in the durtion of the probing pulse and a change in the type of window function were evaluated. An empirical dependence of signal losses during propagation in radio channels of LFM GPR has been established. …”
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Different action of glucocorticoid receptor in adipose tissue remodelling to modulate energy homeostasis by chronic restraint stress by Yinghua Luo, Qinyu Liu, Yaqian Mao, Junping Wen, Gang Chen

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Compact, Energy Efficient Simultaneous Transmission of Analog and Different Digital Signals With a Single Ring Modulator by Mohamed I. Hosni, Younus Mandalawi, Janosch Meier, Ahmed H. Elghandour, Linjie Zhou, Thomas Schneider

“…All results were achieved without any power-consuming pre- or postprocessing to adapt the signals to the transfer function of the modulators. The simultaneous transmission of analog and digital signals in a device with a small footprint and low power consumption may be especially advantageous for future access networks.…”
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Unravelling the role of ubiquitin-specific proteases in breast carcinoma: insights into tumour progression and immune microenvironment modulation by Huiyuan Yang, Tingting Sun, Zhenni Sun, Haining Wang, Dongjie Liu, Dapeng Wu, Tao Qin, Mi Zhou

“…Deubiquitination, an essential epigenetic modification, is regulated by deubiquitinating enzymes (DUBs) and plays a critical role in immune function and tumor progression. Ubiquitin-specific proteases (USPs), a prominent subgroup of DUBs, are involved in regulating immune cell functions, antigen processing, and T cell development in the context of breast cancer. …”
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EGF-Receptor against Amphiregulin (AREG) Influences Costimulatory Molecules on Monocytes and T Cells and Modulates T-Cell Responses by Stephan Dreschers, Christopher Platen, Louise Oppermann, Caitlin Doughty, Andreas Ludwig, Aaron Babendreyer, Thorsten W. Orlikowsky

“…Here, we tested the hypothesis that AREG influences costimulatory monocyte functions, which are crucial for T-cell responses. …”
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Repurposing of CNS accumulating drugs Gemfibrozil and Doxylamine for enhanced sensitization of glioblastoma cells through modulation of autophagy by Smita Dey, Prerika Mathur, Sudeshna Mukherjee, Rajdeep Chowdhury, Syamantak Majumder, Aniruddha Roy, Shibasish Chowdhury

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Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment—Progresses in Their Use in Combined Cancer Therapy by Adrián Povo-Retana, Rodrigo Landauro-Vera, Carlota Alvarez-Lucena, Marta Cascante, Lisardo Boscá

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Capacity Planning and Operation Strategy of New PV-Storage Power Station Based on Frequency Modulation Service by Guoming QIAN, Jie MENG, Haidong ZHU, Quan DING, Xiaoyu CHEN

“…Second, on the basis of the primary and secondary frequency modulation mechanism, the model of PV-Storage power station participating in power grid frequency modulation capacity planning is established with the maximization of the frequency modulation revenue as the optimization objective function. …”
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Neuronal ion channel modulation by Drimys winteri compounds: Opening a new chemical space to neuropharmacology by Macarena E. Meza, Oscar Ramirez-Molina, Oscar Flores, Katherine Fariña-Oliva, Pamela A. Godoy, Jorge Fuentealba, Gonzalo E. Yévenes

“…Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction, which depend on the function of ion channels. Due to their critical involvement in health and disease, the search for new compounds that modulate these proteins is still relevant. …”
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Modulation of Anopheles stephensi gene expression by nitroquine, an antimalarial drug against Plasmodium yoelii infection in the mosquito. by Jian Zhang, Shuguang Zhang, Yanyan Wang, Wenyue Xu, Jingru Zhang, Haobo Jiang, Fusheng Huang

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Sphingosine 1-phosphate receptor 1 modulators exert neuroprotective effects in central nervous system disorders by Shouming Chen, Shouming Chen, Lan Wu, Lan Wu, Bingchen Lang, Bingchen Lang, Guoyan Zhao, Guoyan Zhao, Wensheng Zhang, Wensheng Zhang

“…The sphingosine 1-phosphate (S1P) signaling pathway has important and diverse functions. S1P receptors (S1PRs) are involved in the regulation of lymphocyte trafficking, cardio-cerebral function, vascular permeability, and bronchiolar tone, and have been recognized as therapeutic targets for a variety of diseases. …”
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Auricularia polytricha noodles prevent hyperlipemia and modulate gut microbiota in high-fat diet fed mice by Donglu Fang, Dan Wang, Gaoxing Ma, Yang Ji, Huihua Zheng, Hui Chen, Mingwen Zhao, Qiuhui Hu, Liyan Zhao

“…Auricularia polytricha possesses hypolipidemic effects and decreases lipid accumulation, leading to potential food additives for functional food processing. In this research, we explored the potential effects of A. polytricha noodles on hyperlipidemia and gut microbiota dysbiosis, and elucidated their possible regulatory mechanisms on lipid metabolism in high-fat diet (HFD) mice. …”
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Influence of auditory-based cognitive training on auditory resolution, executive function, and working memory skills in individuals with mild cognitive impairment – a pilot randomi... by Kishan MM, Priya G, Gopee Krishnan, VaniLakshmi R

“…Conclusion Auditory-based cognitive training may improve auditory processing and executive function in older adults with mild cognitive impairment (MCI). …”
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Intranasal oxytocin modulates brain activity during emotional processing in children with treatment resistant conduct problems by Suzanne O’ Brien, Arjun Sethi, James Blair, John Tully, Daniel Martins, Hester Velthuis, Marija M. Petrinovic, Stephen Scott, Nigel Blackwood, Declan G.M. Murphy, Michael C. Craig

“…Twenty boys (mean age 9.85±1.26 years) with persistent CP underwent functional magnetic resonance imaging in a within-subject randomised control design to investigate whether, compared to placebo, a single-dose of intranasal oxytocin could ‘shift’ abnormal neural processing to fear. …”
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Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Modulate Chemoradiotherapy Response in Cervical Cancer Spheroids by Kesara Nittayaboon, Piyatida Molika, Rassanee Bissanum, Kittinun Leetanaporn, Nipha Chumsuwan, Raphatphorn Navakanitworakul

“…Previous research has focused on BM-MSCs, demonstrating their functional involvement in cancer progression as mediators in the tumor microenvironment. …”
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Mitochondrial modulation treating postoperative cognitive dysfunction neuroprotection via DRP1 inhibition by Mdivi1 by Jun Ying, Xiaobing Deng, Ruini Du, Qiyang Ding, Hao Tian, Yue Lin, Bin Zhou, Wei Gao

“…Abstract This study investigated the role of mitochondrial dynamics in postoperative cognitive dysfunction (POCD) and assessed the therapeutic potential of mitochondrial modulation, particularly through the inhibition of dynamin-related protein 1 (DRP1) with Mdivi-1. …”
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Glycerol-assisted grain modulation in femtosecond-laser-induced photochemical synthesis of patterned ZnO nanomaterials by Yingchen Wang, Songyan Xue, Yinuo Xu, Jing Long, Binzhang Jiao, Hui Gao, Xuhao Fan, Yuncheng Liu, Leimin Deng, Wei Xiong

“…ZnO nanomaterials have become appealing for next-generation micro/nanodevices owing to their remarkable functionality and outstanding performance. However, in-situ, one-step, patterned synthesis of ZnO nanomaterials with small grain sizes and high specific surface areas remains challenging. …”
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