HJT-sRNA-m7 bencaosome modulates fibrosis progression in a silicosis mouse model by CHANG Jiahui, REN Pengju, ZHOU Yunyi, JIANG Chengyu, ZHANG Yanli

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Optical Comparator for 4-Bit and 6-Bit QPSK-Modulated Signals by Using Optical Delayed Interferometer by Yohei AIKAWA

“…In this paper, a novel optical comparison operation for phase-shift keying (PSK) modulated signal has been proposed by using optical delayed interferometer to realize an advanced functional component for future optical network. …”
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How do various strategies for returning residues change microbiota modulation: potential implications for soil health by Nan Jiang, Nan Jiang, Zhenhua Chen, Zhenhua Chen, Yi Ren, Shichang Xie, Zimeng Yao, Zimeng Yao, Dongqi Jiang, Yulan Zhang, Yulan Zhang, Lijun Chen, Lijun Chen

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Setting the tone for the day: Cortisol awakening response proactively modulates fronto-limbic circuitry for emotion processing by Changming Chen, Bingsen Xiong, Wenlong Tan, Yanqiu Tian, Shouwen Zhang, Jianhui Wu, Peng Song, Shaozheng Qin

“…These results indicate that the CAR proactively modulates fronto-limbic functional organization for emotion processing in male adults. …”
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The pleiotropic effects of statins: a comprehensive exploration of neurovascular unit modulation and blood–brain barrier protection by Jia-Cheng Liu, Shuang-Yin Lei, Dian-Hui Zhang, Qian-Yan He, Ying-Ying Sun, Hong-Jing Zhu, Yang Qu, Sheng-Yu Zhou, Yi Yang, Chao Li, Zhen-Ni Guo

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The Role of Neurotrophic Modulation in COPD and Its Influence on Airway Pathophysiology: A Systematic Review and Meta-Analysis by Zeeshan Hussain, Mona Rani, Soobia Pathan, Seemi Tanvir, Madeeha Minhas, Saif Ur Rahman, Muhammad Arsalan Shah

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Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study by Bader O. Almutairi, Ahmed Rady, Bashayer S. Aljuhani, Mikhlid H. Almutairi

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Deciphering the role of hsa-piR-775 in primary ovarian insufficiency through FOXG1 modulation by Hui Ding, Xuewei Qin, Yu Li, Yuan Fang, Lina Wu

“…Target gene prediction and enrichment analysis implicated FOXG1, a gene associated with ovarian function, as a potential target of hsa-piR-775. In vitro validation confirmed hsa-piR-775 can influence FOXG1 mRNA, reducing FOXG1 expression. …”
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Microbiota modulation for infectious complications following allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies by Wei Dai, Xiaofan Chen, Huanhuan Zhou, Ning Liu, Mengdi Jin, Zhi Guo

“…Through the use of probiotics, prebiotics, synbiotics, and fecal microbiota transplantation (FMT), these interventions modulate the gut microbiota and enhance immune function to prevent and treat infections. …”
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Bioinformatics Identification of Lactate‐Associated Genes in Hepatocellular Carcinoma: G6PD's Role in Immune Modulation by Hao‐ran Qu, Chao‐qun Wang, Su‐juan Sun, Wen‐wen Zhang, Cheng‐hao Liu, Xuan‐shuang Du, Yao‐yi‐ao Shu, Xi‐cheng Wang, Qin Pan, Feng‐ling Luo, Hong‐yan Wu, Xiao‐lian Zhang, Min Liu

“…Functional assays in HepG2 cells confirmed that alterations in G6PD expression affect T cell activity, with knockdown enhancing IFN‐γ production and overexpression inhibiting it, demonstrating G6PD's role in immune evasion. …”
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Propofol Suppresses Ferroptosis via Modulating eNOS/NO Signaling Pathway to Improve Traumatic Brain Injury by Zi‐Lei Zheng, Xu‐Peng Wang, Yu‐Fei Hu, Wen‐Guang Li, Qi Zhou, Fang Xu, Qiu‐Jun Wang

“…Nissl staining demonstrated enhanced neuronal function, while TUNEL staining indicated reduced neuronal apoptosis. …”
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Boosting Psychotherapy With Noninvasive Brain Stimulation: The Whys and Wherefores of Modulating Neural Plasticity to Promote Therapeutic Change by Daniele Saccenti, Leonor J. Romero Lauro, Sofia A. Crespi, Andrea S. Moro, Alessandra Vergallito, Regina Gregori Grgič, Novella Pretti, Jacopo Lamanna, Mattia Ferro

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NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage. by Harikrishnan Balachandran, Kyle Kroll, Karen Terry, Cordelia Manickam, Rhianna Jones, Griffin Woolley, Tammy Hayes, Amanda J Martinot, Ankur Sharma, Mark Lewis, Stephanie Jost, R Keith Reeves

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OsNUDX23 regulates early seed germination by modulating ROS balance and starch metabolism in rice by Xing Dai, Xing Dai, Wenwen Kong, Feiyan Wu, Zijie Pan, Lei Gao, Beixin Mo, Yu Yu, Weigui Luo

“…Reactive Oxygen Species (ROS) play a dual role during seed germination: at low concentrations, they function as signaling molecules to facilitate germination, while at high levels, they can induce oxidative damages. …”
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Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway by Shaohui Geng, Jingqi Wen, Chunli Shen, Li Liu, Yijin Jiang, Jingyuan Fu, Yiwei Guan, Zi Ye, Yuanhao Wu, Chen Li, Guangrui Huang

“…In contrast, low-dose celastrol suppressed PI3K-Akt signaling by downregulating mTOR, indicating dose-dependent modulation of immune function.ConclusionOur study demonstrates the dose-dependent immunotoxic effects of celastrol, which is toxic in high doses caused by activation of the PI3K-Akt signaling pathway, while low doses offer protection by blocking this signaling pathway. …”
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Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart by Rohini Dhat, Dattatray Mongad, Sivarupa Raji, Silpa Arkat, Nitish R. Mahapatra, Nishant Singhal, Sandhya L. Sitasawad

“…Diabetic and vehicle control animals were randomly divided into groups with/without AKG treatment. Cardiac function was monitored by performing cardiac catheterization. …”
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Unlocking mRNA Vaccine Potential in Liver Cancer Treatment via Synergistic Bile Acid Modulation by Yuqian Wang, Rui Han, Changquan Ling

“…This Letter to the Editor explores synergistic mechanisms enhancing mRNA cancer vaccine efficacy through bile acid metabolism modulation in liver cancer treatment. The latest evidence indicates that bile acids significantly impair T cell function within the liver cancer microenvironment, creating an immunosuppressive milieu that hampers anti-tumor responses. …”
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Osteocytic vinculin controls bone mass by modulating Mef2c-driven sclerostin expression in mice by Yishu Wang, Jianmei Huang, Sixiong Lin, Lei Qin, Dingyu Hao, Peijun Zhang, Shaochuan Huo, Xuenong Zou, Di Chen, Guozhi Xiao

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Melatonin modulates the Notch1 signaling pathway and Sirt3 in the hippocampus of hypoxic-ischemic neonatal rats by Atefeh Mohammadi, Water Balduini, Silvia Carloni

“…Abstract The Notch1 signaling pathway plays a crucial role in the development of the central nervous system, governing pivotal functional activities in the brain, such as neurogenesis. …”
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Rest-task modulation of fMRI-derived global signal topography is mediated by transient coactivation patterns. by Jianfeng Zhang, Zirui Huang, Shankar Tumati, Georg Northoff

“…Recent resting-state functional MRI (fMRI) studies have revealed that the global signal (GS) exhibits a nonuniform spatial distribution across the gray matter. …”
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