Timp2 loss-of-function mutation and TIMP2 treatment in a murine model of NSCLC: Modulation of immunosuppression and oncogenic signaling by David Peeney, Sarvesh Kumar, Tej Pratap Singh, Yueqin Liu, Sandra M. Jensen, Ananda Chowdhury, Sasha Coates-Park, Joshua Rich, Sadeechya Gurung, Yu Fan, Daoud Meerzaman, William G. Stetler-Stevenson

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Probiotics may improve vaginal microbiota, metabolic disorders and ovarian function-related markers by modulating gut microbiota in POI mice by Jinxiang Cao, Wenjie Ma, Xiaoxia Chang, Danhua Pu, Rongrong Tan, Luanqian Hu, Tongtong Hong, Yugui Cui, Li Gao, Jie Wu

“…Conclusions Probiotics may mitigate vaginal microbiota disruption, alleviate lipid metabolism disorders and improve indicators related to ovarian function by modulating the dysbiosis of gut microbiota in POI mice. …”
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Selective Modulation of Osteoclast Function by <i>Bothrops moojeni</i> Venom and Its Fractions: Implications for Therapeutic Targeting in Bone Diseases by Fernanda D’Amélio, Hugo Vigerelli, Isabel de Fátima Correia Batista, Rodrigo Pinheiro Araldi, Álvaro R. B. Prieto-da-Silva, Daniel Carvalho Pimenta, Irina Kerkis

“…These components primarily target cytoskeletal integrity and transcription regulation, with the OBSCN gene playing a direct role in OC function. In contrast, the low-molecular-weight (LMW) fraction selectively modulates OCs without significant cytoskeletal alterations. …”
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E2F2 Reprograms Macrophage Function By Modulating Material and Energy Metabolism in the Progression of Metabolic Dysfunction‐Associated Steatohepatitis by Zheng Liu, Hao Wang, Yuan Liang, Mu Liu, Qiyuan Huang, Mingming Wang, Jinren Zhou, Qingfa Bu, Haoming Zhou, Ling Lu

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Dexmedetomidine Improves Learning Functions in Male Rats Modeling Cognitive Impairment by Modulating the BDNF/TrkB/CREB Signaling Pathway by Sinan Saral, Tolga Mercantepe, Atilla Topçu, Ali Koray Kaya, Aykut Öztürk

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GOJI Supplements Mitigate LPS-Induced Muscle Dysfunction in Rats Through Modulation of Inflammation, Mitochondrial Function, and Muscle Fiber Composition by Xiaobo Liu, Hemalata Deshmukh, Pin-Hsueh Lee, Dawei Li, Patrick Pham, Maomen M Elmassry, Meenu Sharma, Dale M Dunn, Scott Trasti, Chwan-Li Shen

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Convolutional networks can model the functional modulation of the MEG responses associated with feed-forward processes during visual word recognition by Marijn van Vliet, Oona Rinkinen, Takao Shimizu, Anni-Mari Niskanen, Barry Devereux, Riitta Salmelin

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Lactococcus petauri LZys1 modulates gut microbiota, diminishes ileal FXR-FGF15 signaling, and regulates hepatic function by Ouyang Li, Yingshun Zhou, Dayoung Kim, Han Xu, Zhijun Bao, Fan Yang

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Nitazoxanide Modulates Mitochondrial Function and Inflammatory Metabolism in Chondrocytes from Patients with Osteoarthritis via AMPK/mTORC1 Signaling by Ha Eun Kim, Jong Yeong Lee, Ga-Yeon Son, Jun-Young Park, Ki Bum Kim, Chul-Min Choi, Young Jae Moon, Jin Kyeong Choi

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Tai Chi as a mind-body exercise modulates endothelial function in coronary artery disease: A randomized clinical trial by Yameng Li, Cuihan Li, Jiansheng Wen, Meize Cui, Qiuyang Wei, Mingyu Liu, Zaihao Chen, Hui Fang, Linli Liu, Jiahao Fu, Jianwei Zhang, Shaojun Lyu

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Prefrontal executive function enhanced by prior acute inhalation of low-dose hypoxic gas: Modulation via cardiac vagal activity by Dongmin Lee, Yudai Yamazaki, Ryuta Kuwamizu, Masahiro Okamoto, Hideaki Soya

“…We hypothesized that acute low-dose hypoxia leads to enhanced executive function via CVA modulation. Twenty-six individuals participated in both normobaric hypoxia (NH; FIO₂: 13.5 %) and normoxia (NN; ambient air) conditions. …”
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ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia by Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Carlos A. Orozco Castaño, Carlos A. Orozco Castaño, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Nataly Cruz-Rodriguez, Rafael Parra-Medina, Rafael Parra-Medina, Sandra Quijano, Jovanny Zabaleta, Alba Lucia Combita, Alba Lucia Combita, Alba Lucia Combita

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The Effects of Indirect and Direct Modulation of Endocannabinoid System Function on Anxiety-Related Behavior in Mice Assessed in the Elevated Plus Maze Test by Marta Kruk-Slomka, Agnieszka Dzik, Grazyna Biala

“…Background: The endocannabinoid system (ECS) is one of the most important systems modulating functions in the body. The ECS, via cannabinoid (CB: CB1 and CB2) receptors, endocannabinoids occurring in the brain (e.g., anandamide (AEA) and 2-arachidonoylglycerol (2-AG)) and enzymes degrading endocannabinoids in the brain (fatty-acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)), plays a key role in the regulation of mood and anxiety. …”
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Sub-inhibitory concentrations of oxacillin modulate biogenesis and function of extracellular vesicles secreted by oxacillin-sensitive methicillin-resistant Staphylococcus aureus by Zhaoxia Ran, Zhaoxia Ran, Minghui Hao, Binxin Guo, Junrui Wang, Junrui Wang

“…Notably, EV1/2MIC exhibited more pronounced functional changes and enhanced hemolytic activity against rabbit red blood cells. …”
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Effects of Asm-024, A Modulator of Acetylcholine Receptor Function, On Airway Responsiveness and Allergen-Induced Responses in Patients with Mild Asthma by Louis-Philippe Boulet, Gail M Gauvreau, Donald W Cockcroft, Beth Davis, Luc Vachon, Yvon Cormier, Paul M O’Byrne

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IGFBP2 Modulates Trophoblast Function and Epithelial–Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway by Shengping Meng, Yanping Qin, Chunyan Lyu, Sumei Wang

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Impaired Caveolae Function and Upregulation of Alternative Endocytic Pathways Induced by Experimental Modulation of Intersectin-1s Expression in Mouse Lung Endothelium by Dan N. Predescu, Radu Neamu, Cristina Bardita, Minhua Wang, Sanda A. Predescu

“…Intersectin-1s (ITSN-1s), a protein containing five SH3 (A-E) domains, regulates via the SH3A the function of dynamin-2 (dyn2) at the endocytic site. …”
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The Important Role of Dendritic Cell (DC) in iNKT-Mediated Modulation of NK Cell Function in Chlamydia pneumoniae Lung Infection by Lei Zhao, Xiaoling Gao, Hong Bai, Antony George Joyee, Shuhe Wang, Jie Yang, Weiming Zhao, Xi Yang

“…The results provided evidence on the modulating effect of iNKT cell on NK cell function, particularly the critical role of DCs in this modulation process. …”
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Chronic exercise improves renal AT1 and ETB receptor functions via modulating GRK4 expression in obese Zucker rats by Jingjing Lu, Zhengsheng Li, Yinan Yang, Fangning Wei

“…Moreover, exercise training reduced the Candesartan-induced an increase in diuresis and natriuresis and increased ETBR agonists (BQ3020)-mediated diuresis and natriuresis in obese Zucker rats, which were associated with decreased renal AT1R expression and ETBR phosphorylation levels.Conclusions The results demonstrate that exercise training lowers blood pressure via improving renal AT1R and ETBR function through modulating GRK4 expression in Obese Zucker Rats and provides potentially effective targets for obesity-related hypertension.…”
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Autophagy modulation by hADSCs and green light therapy alleviates inflammation and promotes functional recovery after spinal cord injury by Junjie Chen, Quanxin He, Huan Xie, Bin Gu, Liyi Zhou, Daoyuan Jiang, Hongxin Xie, Li Liang, Zhilai Zhou, Hui Zhang

“…This study investigated the therapeutic effects of human adipose-derived mesenchymal stem cells (hADSCs) transplantation combined with green light (GL) therapy to modulate inflammation, enhance autophagy, and facilitate functional restoration post-SCI. …”
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