Reprogramming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation by Israel Ríos, Cristina Herrero, Mónica Torres-Torresano, Baltasar López-Navarro, María Teresa Schiaffino, Francisco Díaz Crespo, Alicia Nieto-Valle, Rafael Samaniego, Yolanda Sierra-Palomares, Eduardo Oliver, Fernando Revuelta-Salgado, Ricardo García-Luján, Paloma Sánchez-Mateos, Rafael Delgado, Amaya Puig-Kröger, Angel L Corbí

“…Since the anti-inflammatory/pro-fibrotic macrophage profile is determined by MAFB, whose activity/protein levels are regulated by GSK3, we addressed the macrophage reprogramming potential of GSK3 modulation. GM-CSF-dependent (GM-MØ) and M-CSF-dependent monocyte-derived macrophages (M-MØ) exhibited distinct levels of inactive GSK3, and inhibiting GSK3 in GM-MØ led to the acquisition of transcriptional, phenotypic, and functional properties characteristic of M-MØ (enhanced expression of IL-10 and monocyte-recruiting factors, and higher efferocytosis). …”
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Modulating carboxymethylcellulose-based hydrogels with superior mechanical and rheological properties for future biomedical applications by N. A. Dahlan, S. Y. Teow, Y. Y. Lim, J. Pushpamalar

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Radiotherapy resistance driven by Asparagine endopeptidase through ATR pathway modulation in breast cancer by Macarena Morillo-Huesca, Ignacio G. López-Cepero, Ryan Conesa-Bakkali, Mercedes Tomé, Colin Watts, Pablo Huertas, Gema Moreno-Bueno, Raúl V. Durán, Jonathan Martínez-Fábregas

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Metabolic analysis of sarcopenic muscle identifies positive modulators of longevity and healthspan in C. elegans by Steffi M. Jonk, Alan Nicol, Vicki Chrysostomou, Emma Lardner, Shu-Che Yu, Gustav Stålhammar, Jonathan G. Crowston, James R. Tribble, Peter Swoboda, Pete A. Williams

“…Skeletal muscle is a source of systemic metabolites and macromolecules important for neuronal health, function, and healthy neuronal aging. Age-related loss of skeletal muscle might result in decreased metabolite and macromolecule availability, resulting in reduced neuronal function or increased susceptibility to unhealthy aging and neurodegenerative diseases. …”
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Feedback from an avatar facilitates risk-taking by modulating the amygdala response to feedback uncertainty. by Toshiko Tanaka, Masahiko Haruno

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APPLIED DIAGNOSTIC MODULE FOR DETERMINING COGNITIVE MODEL PARAMETERS OF SUBJECTS OF EDUCATION IN AN ADAPTIVE ENVIRONMENT by Anatoly N. Vetrov

“…Objectives To increase the functional efficiency of information and educational environments created by automated training systems by realising individually oriented formation of knowledge using adaptive generation of heterogeneous educational influences based on an innovative block of parametric cognitive models and a set of programs to support the automation of research tasks. …”
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Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response. by Susanna R Bidgood, Jerzy Samolej, Karel Novy, Abigail Collopy, David Albrecht, Melanie Krause, Jemima J Burden, Bernd Wollscheid, Jason Mercer

“…Using targeted repression and/or deletion viruses we found that deletion of individual LB-redox proteins was insufficient for host redox modulation suggesting there may be functional redundancy. …”
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Astragaloside IV represses hepatocellular carcinoma progression by modulating HMGB1-ferroptosis axis by Xingyang Zhao, Ruizhe Liu, Haiyu Zhou, Deqing Wu

“…Abstract Astragaloside IV (AST-IV), as one of the main functional components of Astragalus membranaceus, has physiological functions such as regulating metabolism and anti-tumor. …”
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RNA N6-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice by Bochuan Li, Ting Zhang, Mengxia Liu, Zhen Cui, Yanhong Zhang, Mingming Liu, Yanan Liu, Yongqiao Sun, Mengqi Li, Yikui Tian, Ying Yang, Hongfeng Jiang, Degang Liang

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CLK2 blockade modulates alternative splicing compromising MYC‐driven breast tumors by Fernando Salvador, Roger R Gomis

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C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2. by Bedoor Qabazard, Samanza Ahmed, Ling Li, Volker M Arlt, Philip K Moore, Stephen R Stürzenbaum

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Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior by Eunyoung Kim, Hairuo Du, Yanqi Tan, Brandon L. Brown, Yaowen Chang, Blanca Díaz-Castro, Jonathan V. Sweedler, Xinzhu Yu

“…Abstract Accumulating evidence has supported diverse regulatory functions of astrocytes in different neural circuits as well as various aspects of complex behaviors. …”
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Rhizobium biostimulation of blackberry modulates survival pathways in Caenorhabditis elegans across biological kingdoms by Rocío Roca-Couso, José David Flores-Félix, Begoña Ayuda-Durán, Rebeca Ferreras-Charro, Ignacio García-Estévez, Paula García-Fraile, Raúl Rivas

“…This work underscores the potential of endophytic bacteria to contribute to sustainable agriculture and functional food innovation through molecular and physiological modulation in both plants and animal models.…”
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Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation by Shuai Ji, Freed Ahmad, Baizhao Peng, Ying Yang, Mengting Su, Xiaoshan Zhao, Tommi Vatanen

“…Conclusions FMT leads to significant taxonomic, functional, and lifestyle shifts in recipient phageome composition. …”
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Synthesis and Mesomorphic Properties of Geometric and Conformation-Modulated Amphiphilic β-Cyclodextrin Liquid Crystals by Austin Che, Homayoun Ghaseminezhad, Carson O. Zellmann-Parrotta, Jessica Duong, Vance E. Williams, Chang-Chun Ling

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Bandgap Engineering in InAs/GaSb II Superlattices: Modulation and Vacancy Defects Analysis by Yan Jiang, Yulin Zhou, Zongyao Zhang, Zhengdao Li, Liyuan Jiang, Xinxin Zhao, Jianbao Wu

“…The computational analysis of InAs/GaSb type-II superlattices utilizing density functional theory (DFT) with pseudopotentials has been performed. …”
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Controlling the transverse multipole components in rf cavity modes using the azimuthal modulation method by L. M. Wroe, W. Wuensch, R. J. Apsimon

“…The derived equations explicitly show the radial variation of the change in longitudinal and transverse momentum follows a polynomial rather than Bessel-function relationship. The expression for the longitudinal electric field is then compared to a field map obtained from the 3D electromagnetic simulation of an azimuthally modulated cavity designed to support a mode composed of monopole, dipole, and quadrupole components. …”
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High-speed algorithm for carrier frequency recovery and frame synchronization in QPSK-modulated modems by A. V. Sadchenko, O. A. Kushnirenko, E. K. Koshelev, V. I. Bondar

“…In most QPSK modems, the carrier frequency recovery and synchronization recovery tasks are separated and solved with the help of different functional modules, which is not the optimal solution from the point of view of increasing the energy efficiency. …”
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Publisher Correction: Uniaxial strain tuning of charge modulation and singularity in a kagome superconductor by Chun Lin, Armando Consiglio, Ola Kenji Forslund, Julia Küspert, M. Michael Denner, Hechang Lei, Alex Louat, Matthew D. Watson, Timur K. Kim, Cephise Cacho, Dina Carbone, Mats Leandersson, Craig Polley, Thiagarajan Balasubramanian, Domenico Di Sante, Ronny Thomale, Zurab Guguchia, Giorgio Sangiovanni, Titus Neupert, Johan Chang

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The Angiostrongylus vasorum Excretory/Secretory and Surface Proteome Contains Putative Modulators of the Host Coagulation by Nina Germitsch, Nina Germitsch, Tobias Kockmann, Lars M. Asmis, Lucienne Tritten, Manuela Schnyder

“…Proteins were quantified by liquid chromatography coupled to mass spectrometry and functionally characterized through gene ontology and pathway enrichment analysis. …”
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