INFORMATION SUPPORT FOR CROWDFUNDING AND INVESTING PROJECTS by Julia Malieieva, Olga Malyeyeva, Anatolii Demchenko, Lidiia Piddubna

“…The following tasks are solved: research of functional possibilities of existing crowdfunding platforms; development and configuration of expansion modules for the selected framework; development of the interface of the financial manager of the project with real estate. …”
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Modulation of the immune microenvironment using nanomaterials: a new strategy for tumor immunotherapy by Haozhe Piao, Yuxin Jiang, Yuxin Jiang, Shengbo Jin, Jie Shi, Jun Yu, Wenping Wang, Zhenguang Du, Huini Yao, Qian Liu, Ningxin Li, Jiaqing Fu, Yue Shen, Mingzhu Li

“…Over the past few years, nanomaterials, owing to their unique physicochemical properties, multifunctionality, and good targeting ability, have gradually become important tools for modulating the immune microenvironment. By precisely delivering immunomodulatory factors, nanomaterials can effectively activate dendritic cells (DCs), enhance the function of effector T cells, and reverse the immunosuppressive state of tumor-associated macrophages (TAMs). …”
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YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation by Cong Huang, Wenting Li, Changbing Shen, Bin Jiang, Kaoyuan Zhang, Xiahong Li, Weilong Zhong, Zizhuo Li, Zhenzhen Chen, Chaofeng Chen, Xingling Jian, Xiaoming Liu, Haiyan Huang, Lili Yang, Bo Yu

“…However, its precise function and mechanism in psoriasis pathogenesis are still not well-clarified. …”
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Phosphorylation-Directed Antibodies in High-Flux Screens for Compounds that Modulate Signal Transduction by John A. Alberta, Charles D. Stiles

“…In this paper, we show how phosphorylation-directed antibodies can be used in a colorimetric, high-throughput screen for drugs that modulate the function of specific growth factor receptors or signal-generating proteins.…”
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Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in Cryptococcus neoformans by Ci Fu, Nicole Robbins, Leah E. Cowen

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Exploring the Antifibrotic Mechanisms of Ghrelin: Modulating TGF-β Signalling in Organ Fibrosis by Mei Li, Chang Zheng, Huiyi Wang, Shan Wang

“…This imbalance can lead to compromised organ function and potential failure, posing significant health risks. …”
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Design of Multiple Power Supply Mechanisms High Frequency Auxiliary Converter Module by Xuerong LI, Hao XU, Wei FAN, Jianbo LUO

“…TLbuck transform, LLC resonance transform and three-phase inverter function were integrated in the module, which involved a variety of IGBT devices with different voltage levels, and solved the problem of voltage withstand of low-voltage devices under high-voltage conditions, suiting AC and DC power supply. …”
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Gene therapy for hearing loss: challenges and the promise of cellular plasticity and epigenetic modulation by Samprita Das, Uri Manor

“…While gene therapy holds immense promise for restoring hearing function in cases of hereditary hearing loss (HHL), current methods face certain challenges that must be overcome to successfully develop therapeutic approaches. …”
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Integrated Waveform Design of Radar and Communication Based on Chirp-rate Hopping Modulation by G. Q. Zhang, X. Rao, J. L. Fu, W. W. Hu, J. F. Hu

“…The performance of the CrHM signal is analyzed, including the ambiguity function, the principle of demodulation, and the robust properties of demodulation. …”
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Vitamin D immune modulation of the anti-inflammatory effects of HDL-associated proteins by Hanaa Mousa, Susu M. Zughaier

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fMRI-based explanations for how meditation could modulate pain processing by Faly Golshan, Marla J. S. Mickleborough

“…Drawing on findings from functional magnetic resonance imaging (fMRI) studies, general models are categorized to explain how meditation alters cortical responses in both naïve and expert practitioners when exposed to pain stimuli. …”
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Validation of Quarter-Life Management Program Module Based on Solution-Focused Therapy by Eva Rahman, Nida Ul Hasanat

“…The functional validation procedure was carried out through experimental research on 7 participants in experimental groups and 7 participants in waitlist-control group. …”
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Critical modulation frequency and critical band based on random amplitude and frequency changes by A. SĘK

“…Random amplitude and frequency changes of the simple tone were produced in the amplitude and frequency modulation process by random modulating signals. The results of the investigations enable to state that the critical modulation frequency is an increasing function of the carrier frequency. …”
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Dissociable neural mechanisms underlying the modulation of pain and anxiety? An FMRI pilot study. by Katja Wiech, Robert Edwards, Graham Lorimer Moseley, Chantal Berna, Markus Ploner, Irene Tracey

“…Safety signaling engaged elements of the descending pain control system, including the rostral anterior cingulate cortex that showed increased functional connectivity with the periaqueductal gray and VLPFC. …”
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Cellular enzyme-modulating activity of p-acetoxycinnamyl alcohol from Alpinia officinarum by Chang-Dae Lee, Hyosun Lim, Hak-Dong Lee, Sullim Lee, In Young Bae, Sanghyun Lee

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Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen by Sriram Ravindran, Marc Schapira, Philip A. Patston

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Stage-specific modulation of Drosophila gene expression with muscle GAL4 promoters by Ziwei Zhao, Erika R Geisbrecht

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Top-down modulation of sensory processing and mismatch in the mouse posterior parietal cortex by Constanze Raltschev, Sergej Kasavica, Benjamin Leonardon, Thomas Nevian, Shankar Sachidhanandam

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Research on Performance of Fiber-Based Multiple Apertures Receiver System with PPM Modulation by Kangning LI, Xu FENG, Jianwen GAO, Jing Ma

“…The performance of fi ber-based FSO with multiple apertures receiver system was studied for pulse position modulation (PPM) .Expressions of PPM modulated signal-to-noise ratio (SNR) and bit-error rate (BER) for fi ber-based FSO multiple apertures receiver system were presented based on the probability density function of Gamma-Gamma intencity distribution and non–central chisquare fi ber coupling effi ciency distribution under atmospheric infl uence.Selection combining (SC), equal gain combining (EGC) and maximum ratio combining (MRC) were considered to be three signal combining methods for multiple apertures receiver system.The BER performance of 4PPM modulted SC, EGC and MRC fi ber-based multiple apertures receiver system and single aperture receiver system with the same total aperture area were comparative analyzed by Monte Carlo simulation.The BER performance of fi ber-based multiple apertures receiver systems in 4PPM and 8PPM modulation modes were directly compared for diff erent combining methods.…”
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TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family by Philip Schmiege, Dawid Jaślan, Michael Fine, Nidish Ponath Sadanandan, Alexandra Hatton, Nadia Elghobashi-Meinhardt, Christian Grimm, Xiaochun Li

“…Abstract TRPML2 activity is critical for endolysosomal integrity and chemokine secretion, and can be modulated by various ligands. Interestingly, two ML-SI3 isomers regulate TRPML2 oppositely. …”
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