Cannabinoid Modulation of Excitability and Short-Term Neuronal Dynamics in the Dorsal and Ventral Hippocampus by Giota Tsotsokou, Ioanna-Maria Sotiropoulou, Klearchos Stampolitis, George D. Oikonomou, Aikaterini-Paraskevi Avdi, Costas Papatheodoropoulos

“…Endocannabinoids, acting primarily through CB1 receptors, are critical modulators of neuronal activity, influencing cognitive functions and emotional processing. …”
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Multidimensional advances in neural interface technology for peripheral nerve repair: From material innovation to clinical translation by Jianchao Wu, Qixin Han, Dingkun Gui, Yun Qian

“…Technological breakthroughs include tissue-compliant flexible micro-nano fabrication, wireless self-powered systems, closed-loop neural feedback control, and multimodal precision modulation. Preclinical and clinical researches validated the therapeutic efficacy of neural interfaces in promoting axon regeneration, managing chronic pain, and restoring sensorimotor function. …”
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Probing the modulation of enzyme kinetics by multi-temperature, time-resolved serial crystallography by Eike C. Schulz, Andreas Prester, David von Stetten, Gargi Gore, Caitlin E. Hatton, Kim Bartels, Jan-Philipp Leimkohl, Hendrik Schikora, Helen M. Ginn, Friedjof Tellkamp, Pedram Mehrabi

“…Via this 5D-SSX, time-resolved experiments can now be carried out at physiological temperatures and with long time delays, providing insights into protein function and enzyme catalysis. Our findings demonstrate the temperature-dependent modulation of turnover kinetics for the mesophilic β-lactamase CTX-M-14 and the thermophilic enzyme xylose isomerase, within the full protein structure…”
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Membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper by Elodie Lafargue, Jean-Pierre Duneau, Nicolas Buzhinsky, Pamela Ornelas, Alexandre Ortega, Varun Ravishankar, James Sturgis, Ignacio Casuso, Lucie Bergdoll

“…These findings underscore how lipid heterogeneity and changes in membranes influence VDAC function.…”
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Transcranial optogenetic brain modulator for precise bimodal neuromodulation in multiple brain regions by Hyogeun Shin, Min-Ho Nam, Seung Eun Lee, Soo Hyun Yang, Esther Yang, Jin Taek Jung, Hyun Kim, Jiwan Woo, Yakdol Cho, Youngsam Yoon, Il-Joo Cho

“…Abstract Transcranial brain stimulation is a promising technology for safe modulation of brain function without invasive procedures. …”
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Impact of Viruses on Prokaryotic Communities and Greenhouse Gas Emissions in Agricultural Soils by Xing Huang, Lucas P. P. Braga, Chenxiao Ding, Bokai Yang, Tida Ge, Hongjie Di, Yan He, Jianming Xu, Laurent Philippot, Yong Li

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The efficacy and neuroplasticity of Tuina combined with repetitive transcranial magnetic stimulation in the treatment of post-stroke depression: study protocol for a single-center,... by Zhao Ma, Zhengkun Gao, Xiao Chen, Yuqian Hu, Hang Gao, Jinying Gu, Haoxiang He, Hui Jin, Jiming Tao, Min Fang

“…The primary efficacy outcome is the change from baseline to week 2 in Hamilton Depression Rating Scale (HAMD) and Functional Magnetic Resonance Imaging (fMRI). Secondary efficacy outcomes include other assessments of the Mini-Mental State Examination (MMSE), The modified Barthel index (MBI), The National Institutes of Health Stroke Scale(NIHSS), inflammatory factor (IL-6, IL – 17, TNF-α, IFN-γ, IL-4, IL-10), and Functional near-infrared spectroscopy (fNIRS). …”
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Artificial intelligence-based personalized diet: A pilot clinical study for irritable bowel syndrome by Tarkan Karakan, Aycan Gundogdu, Hakan Alagözlü, Nergiz Ekmen, Seckin Ozgul, Varol Tunali, Mehmet Hora, Damla Beyazgul, O. Ufuk Nalbantoglu

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Emerging therapy targets to modulate microbiome-mediated effects evident in cardiovascular disease by Dorothea Katharina Hoffelner, Tim Hendrikx

“…Notably, metabolites such as short-chain fatty acids, trimethylamine N-oxide, and bile acids, which are influenced by the microbiome and its functional composition, have been implicated in vascular health, immune modulation, and atherosclerosis. …”
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Enhancing visual perception by modulating prestimulus alpha and beta power with tRNS by Jinwen Wei, Huiru Zou, Qianyuan Tang, Ziqing Yao, Gan Huang, Zhen Liang, Li Zhang, Lijie Ren, Xiaodong Cai, Chen Yao, Changsong Zhou, Zhiguo Zhang

“…Further analyses revealed that fatigue influenced the oscillations’ responsiveness to tRNS, and that under low fatigue, alpha power, more than beta, demonstrated greater functional sensitivity to VCT. These findings demonstrate that tRNS can improve perception by modulating alpha/beta oscillations in specific brain states, highlighting the role of brain state in neuromodulation efficacy.…”
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Large-scale signal propagation modes in the human brain by Youngjo Song, Pyeong Soo Kim, Benjamin A. Philip, Taewon Kim

“…Crucially, we demonstrate that the superposition of these modes generates canonical spatiotemporal phenomena—including wave propagation, time-varying functional connectivity, and quasi-periodic patterns. …”
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iTBS on RDLPFC improves performance of motor imagery: a brain-computer interface study combining EEG and fNIRS by Jialin Chen, Quan Liu, Gengbin Chen, Guiyuan Cai, Junbo Jiang, Xueru Yang, Chunqiu Tan, Cailin Zhang, Guangqing Xu, Yue Lan

“…They undertook two MI-BCI training sessions, with electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) used to assess acute neuroplasticity changes. …”
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The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment by Yipin Lu, Peng Xu, Sha Li, Jie Yao

“…Differentially expressed gene (DEG) analysis, functional enrichment analysis (GSEA and KEGG), and spatial transcriptomics were utilized to explore the biological functions and mechanisms of JPT1 in tumor biology. …”
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Long-term effects of infrapatellar fat pad SVF infiltration in knee osteoarthritis management: A prospective cohort study by Klaus Werner Labarre, Gerald Zimmermann

“…The correlation between the number of injected cells and functional improvements was significant for ADL at 6 months (Spearman's rho = 0.31, p = 0.044). …”
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The impact of high-frequency rTMS treatment on brain activity in PSCI patients: a TMS-EEG study by Xinxin Song, Jianming Fu, Yunhai Yao, Yuhong Shu, Zhongli Wang, Xuting Chen, Lianjie Ma, Fang Shen, Xiaolin Sun, Xiaoqing Ma, Ting Zhang, Rujue Jin, Ming Zeng, Xudong Gu

“…Patients with higher education levels exhibited significant cognitive improvement (p = 0.039), while patients with a time since onset of 60–180 days showed a significant decline in cognitive improvement (p = 0.024).ConclusionHigh-frequency rTMS effectively modulated connectivity patterns between the left DLPFC and other brain regions in PSCI patients, enhancing cognitive functions. …”
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Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator by Ainoa Fernández-Olivares, Viviana P Orellana, Jesús Llanquinao, Gonzalo Nuñez, Pablo Pérez-Moreno, Sebastián Contreras-Riquelme, Alberto JM Martin, Fabio Mammano, Ivan E Alfaro, Juan F Calderón, Jimmy Stehberg, Mauricio A Sáez, Mauricio A. Retamal

“…Functional assays were conducted to evaluate its effects on invasion, division, spheroid formation, and mesenchymal marker expression. …”
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Pulse Width Modulation Control of Mecanum-Wheeled Mobile Robot With Random Noise by Ruijie Yin, Zhaojing Wu, Likang Feng

“…As a preliminary, PWM strategy of random nonlinear systems is obtained by the aid of the functional analysis tool. A smooth voltage controller is presented by the backstepping technique for MWMR. …”
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients by Iván Ferraz-Amaro, Iván Ferraz-Amaro, Sergio Santos-Concepción, Javier Castro-Hernández, Maria Vanesa Hernández-Hernández, Beatriz Tejera Segura, Cristina Luna, Esmeralda Delgado-Frias, Federico Díaz-González, Federico Díaz-González, Federico Díaz-González

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Gold and Silver Nanoparticles Efficiently Modulate the Crosstalk Between Macrophages and Cancer Cells by Adamecz DI, Veres É, Papp C, Árva H, Rónavári A, Marton A, Vizler C, Gácser A, Kónya Z, Igaz N, Kiricsi M

“…Since it is fairly unknown how the promising anticancer agents, silver (AgNPs) and gold nanoparticles (AuNPs) affect the bidirectional communication and reprogramming in the tumor stroma, we examined the behavior, the tumor-supporting functions, and the expression of polarization and functional marker genes of TAMs to reveal how these are modulated upon interaction with nanoparticle-exposed cancer cells.Methods: We established co-cultures of murine immortalized J774 or primary bone marrow-derived macrophages with 4T1 breast cancer cells treated with AuNPs or AgNPs or with none of the nanoparticles. …”
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Modulation of Surface Elastic Waves and Surface Acoustic Waves by Acoustic–Elastic Metamaterials by Chang Fu, Tian-Xue Ma

“…Metamaterials enable the modulation of elastic waves or acoustic waves in unprecedented ways and have a wide range of potential applications. …”
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