Wound repair and immune function in the Pseudomonas infected CF lung: before and after highly effective modulator therapy by Emma Lea Matthews, Emma Lea Matthews, Meghan June Hirsch, Meghan June Hirsch, Federico Prokopczuk, Luke I. Jones, Eriel Martínez, Jarrod W. Barnes, Jarrod W. Barnes, Stefanie Krick, Stefanie Krick

“…With the approval of highly effective modulator therapies like elexacaftor/tezacaftor/ivacaftor (ETI), pwCF eligible for ETI have seen drastic improvements in lung function and clinical outcomes, including an increased life expectancy. …”
Get full text

Salivary Function and Quality of Life Following Adaptive Intensity-Modulated Radiotherapy for Locally Advanced Head and Neck Cancer by Wael El-Sheshtawy, Mostafa Mostafa

“…However, the potential role of adaptive radiotherapy in preserving salivary function and enhancing quality of life (QoL) remains underexplored. …”
Get full text

The Synthetic Cannabinoids ADB-FUBINACA Modulate Mitochondrial Function and Dynamics at Biologically Relevant Concentrations During In Vitro Neurodifferentiation by R.F. Malheiro, H. Carmo, F. Carvalho, J.P. Silva

“…Different mechanisms seem to underlie mitochondrial function-related effects, as only the modulation of energy supply was dependent on CB1R activation. …”
Get full text

Chimeric antigen receptor NK-92 cell function is modulated by HLA class I expression of target cells by Nicolai Stransky, Ranran Ji, Lukas Prause, Katrin Ganser, Winfried S. Wels, Peter Ruth, Stephan M. Huber, Franziska Eckert

Get full text

Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation by Heng Zhou, Xiaoling He, Yue Xiong, Yixuan Gong, Yuanyuan Zhang, Shuangli Li, Rui Hu, Ying Li, Xu Zhang, Xin Zhou, Jiang Zhu, Yunhuang Yang, Maili Liu

Get full text

Counteracting Alzheimer's disease via normalizing neurovascular unit with a self-regulated multi-functional nano-modulator by Xue Xia, Ya Wei, Qianqian Huang, Yang Zhou, Xiaorong Wang, Yulong Shi, Xiaotong Yang, Wenqin Yang, Yiwei Zhang, Ting Lei, Yuan Huang, Hanmei Li, Meng Qin, Huile Gao

“…Here, we fabricated a self-regulated muti-functional nano-modulator (siR/PIO@RP) that can intelligently navigate to damaged blood-brain barrier and release therapeutical cargoes for synergetic AD therapy. …”
Get full text

Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Modulation of MITF expression by small molecules affected the differentiation and immunosuppressive function of MDSCs. …”
Get full text

TECHNIQUE OF FUNCTIONAL UNIFICATION OF ADAPTIVE HYDRAULIC DRIVE MODULE CAPABLE OF LOAD STABILIZATION ON THE WORKING BODY OF MOBILE MACHINES by V. A. Pershin, T. A. Khinikadze

Subjects: “…functional unification…”
Get full text

Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity by Gang Wang, Yaobao Han, Ke Peng, Zhilin Jiang, Tingting Wang, Qing Zheng, Wenting Li, Hanbing Xu, Fuhai Ji, Zhen Li

Get full text

Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function by Shujuan Zhang, BangHua Li, Xiaoqun Han, LinLin Ruan, Xingxing Fu, Yanglin Chen, Hongtao Wan, Xiaojian Zhu, Dan Liu, Bo Yi

Get full text

Electronic Modulation of Cu Catalytic Interfaces by Functionalized Ionic Liquids for Enhanced CO₂ Reduction by Chuanhui Wang, Wei Zhou, Jiamin Ma, Zhi Wang, Congyun Zhang

“…In this study, to unravel the molecular-level mechanisms underlying these enhancements, density functional theory calculations (DFTs) were employed to systematically explore how ILs with different terminal groups modulate the electronic reconstruction of the Cu surface, further affecting the *CO–*CO coupling and product selectivity. …”
Get full text

Urodynamic assessment of lower urinary tract function for women with symptoms of stress urinary incontinence. ICS Educational Module by Maurizio Serati, Tufan Tarcan, Anna Padoa, Hashim Hashim, Andrea Braga, Karl Dietrich Sievert, Peter F.W.M. Rosier

Subjects: Get full text

Effects of repetitive transcranial magnetic stimulation on seizure reduction through modulation of functional connectivity in drug-resistant epilepsy by Hayom Kim, Jung Bin Kim

Get full text

Author Correction: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility by Yi Luo, Miriam Barrios-Rodiles, Gagan D. Gupta, Ying Y. Zhang, Abiodun A. Ogunjimi, Mikhail Bashkurov, Johnny M. Tkach, Ainsley Q. Underhill, Liang Zhang, Mohamed Bourmoum, Jeffrey L. Wrana, Laurence Pelletier

Get full text

Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity by Qi Chen, Peiguo Yang

“…Summary: Tripartite motif (TRIM) proteins are E3 ligases with modular structures involved in diverse cellular functions. Whether biomolecular condensation broadly regulates TRIM proteins remains unclear. …”
Get full text

Tendomodulin in pan-cancer analysis: exploring its impact on immune modulation and uncovering functional insights in colorectal cancer by Jingfeng Chen, Qin Hu, Cong Zhang, Aiqi Zhao, Bihua Guan, Yifan Wang, Min Zhang, Xia Li, Biao Chen, Lulu Zeng, Minjiang Chen, Bing Wu, Jianping Wang, Yang Yang, Jiansong Ji

Get full text

A Reconfigurable Optical Logic Gate With up to 25 Logic Functions Based on Polarization Modulation With Direct Detection by Xianfeng Tang, Zhongqin Fang, Yaxue Zhai, Xiangsen Jiao, Na Gao, Xiaoguang Zhang, Lixia Xi, Jianping Li, Wenbo Zhang

Get full text

TDCS Modulates Brain Functional Networks in Children with Autism Spectrum Disorder: A Resting-State EEG Study by Jiannan Kang, Wenqin Mao, Juanmei Wu, Xinling Geng, Xiaoli Li

“…Conclusion: These results suggest that tDCS may be a promising intervention for modulating brain functional networks in children with ASD. …”
Get full text

Not just a gut feeling: a deep exploration of functional bacterial metabolites that can modulate host health by Andrew Gold, Jiangjiang Zhu

Get full text

Corrigendum to “PRMT1 methylates METTL14 to modulate its oncogenic function” [Neoplasia 42 (2023) 100912] by Jingchao Wang, Zhen Wang, Hiroyuki Izunuka, Wenyi Wei, Jing Liu

Get full text