Structure activity relationships of antischistosomal N-phenylbenzamides by incorporation of electron-withdrawing functionalities by Ameera Mohammed Dawoodjee, John Sichinga, Harrison Banda, Steve Mbaya, Evelyn Funjika, Godfrey Mayoka, Christabel Hikaambo, Karol R. Francisco, Yujie Uli Sun, Lawrence J. Liu, Conor R. Caffrey, Peter Mubanga Cheuka

“…Our previous SAR studies, designed by selecting representative substituents from the Craig plot, identified 9 and 11 which possessed electron-withdrawing groups that benefited potency. This study sought to enhance the potency of this chemotype by incorporating other electron-withdrawing functionalities not studied previously and to overcome the potential pharmacokinetic liabilities associated with the high lipophilicity of frontrunner compounds. …”
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A novel indicator for predicting functional recovery in elderly hip fracture patients by Weicheng Wu, Zhening Guo, Peiyao Zhu, Bo Lv, Yongtao Mao, Chang She, Wei Xu, Jun Gu, Jie Pan, Liubing Li, Liubing Li

“…BackgroundThe inflammatory response following hip fracture significantly influences postoperative functional recovery in patients. However, to date, no inflammatory index has been identified as a reliable and accurate predictor of functional recovery, especially in elderly patients with hip fractures. …”
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Modeling functional connectivity with learning and memory in a mouse model of Alzheimer's disease by Lindsay Fadel, Elizabeth Hipskind, Steen E. Pedersen, Jonathan Romero, Caitlyn Ortiz, Caitlyn Ortiz, Eric Shin, Md Abul Hassan Samee, Robia G. Pautler, Robia G. Pautler, Robia G. Pautler

“…Notably, FC changes were also observed in the Default Mode Network, exhibiting a loss of hyperconnectivity over time. Modeling revealed functional connections that support learning and memory performance differ between the 6- and 10-month groups.DiscussionThese ML models show potential for early disease detection by identifying connectivity patterns associated with cognitive decline. …”
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IMPACT OF LEVOSIMENDAN ON RENAL FUNCTION IN COMPLEX TREATMENT OF ACUTE DECOMPENSATED HEART FAILURE by M. V. Lediakhova, S. N. Nasonova, I. V. Zhirov, M. V. Andreevskaya, R. M. Bogieva, T. M. Uskach, M. A. Saidova, V. P. Masenko, S. N. Tereshchenko

“…To study impact of levosimendan on renal function in patients with ADHF with reduced systolic function.Material and methods. …”
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Genomic and functional analysis of isochorismate synthase genes in sugarcane and their roles in disease resistance by Zhen Zeng, Xinyu Zhu, Jiaoyun Chen, Shilong Zhang, Sisi Zhou, Kailin Li, Wankuan Shen

“…This study establishes the groundwork for functional studies of sugarcane ICS genes and enhances our understanding of the mechanisms of disease resistance in sugarcane.…”
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Functional changes in the hypothalamic-pituitary-adrenal axis after successful cardiopulmonary resuscitation by Le An, Zhijiang Qi, Huan Shao, Chunsheng Li

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Thalamic functional dysconnectivity in patients with left-hemisphere chronic capsular and pontine stroke by Jun Guo, Jun Guo, Hongchuan Zhang, Hongchuan Zhang, Jingchun Liu, Caihong Wang, Chen Cao, Jingliang Cheng, Chunshui Yu, Wen Qin

“…The thalamic subfields functional connectivities were compared between groups using a two-way repeated analysis of variance (ANOVA), corrected for confounders including age, gender, education and scanners. …”
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Upper limb functional testing: does age, gender, and sport influence performance? by Camille Tooth, PT, PhD, Cédric Schwartz, PhD, Jean-Louis Croisier, PT, PhD, Amandine Gofflot, PT, Stephen Bornheim, PT, PhD, Bénédicte Forthomme, PT, PhD

“…However, for some evaluations, and especially for functional testing, there is a lack of normative values, which limits the interpretation of the values measured. …”
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Influence of catheter ablation for atrial fibrillation on atrial and ventricular functional mitral regurgitation by Masaharu Masuda, Kimiko Sekiya, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Yasuhiro Matsuda, Yosuke Hata, Hiroyuki Uematsu, Taku Toyoshima, Naoko Higashino, Toshiaki Mano

“…Abstract Aims The purpose of this study was to compare the impact of catheter ablation on cardiac structural reverse remodelling and atrial (AFMR) and ventricular (VFMR) functional mitral regurgitation (MR), and the long‐term prognosis of patients with AFMR and VFMR. …”
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The effect of birthweight and gestational age on cognitive function in midlife: the Bogalusa heart study by Eunsun Gill, David J. Libon, Soo Jung Kang, Ileana De Anda-Duran, Lydia A. Bazzano, Wei Chen, Camilo Fernandez-Alonso, Emily W. Harville

“…Abstract Background Although the relationships between birthweight, gestational age (GA), and cognitive function (CF) before midlife have been demonstrated, the relationships after midlife and potential racial disparities remain inconclusive. …”
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Effect of an 8-week training program on the rebalancing of functional asymmetry in young footballers by Walid Bouzid, Omar Ben Rakaa, Aziz Chokri, Aziz Eloirdi, Abdelmoujoud Elhaboussi, Mohamed Barkaoui

“…Significant reductions in functional asymmetries were observed across all variables and age groups. …”
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Insomnia, cardiorespiratory function and quality of life in individuals with post-COVID-19 fatigue by Nathalea Spode de Arruda, Alessandra Hofstadler Deiques Fleig, Charles Rech, Carine Cristina Callegaro

“…Objective: This study aimed to compare the prevalence of insomnia, lung function, inspiratory muscle function, functional capacity, and quality of life in individuals with and without post-COVID-19 fatigue. …”
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Somatic symptom severity during acute illnesses among children with functional gastrointestinal disorders by Rattanachart Sirinil, Anundorn Wongteerasut

“…Background Functional gastrointestinal disorders (FGIDs) are associated with various gastrointestinal (GI) and non-GI symptoms, risk factors for which commonly include psychosocial and physical stresses. …”
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Body mass index, exercise capacity and functional status in chronic heart failure by Steve R. Noumegni, Arnaud D. Kaze, Gregg C. Fonarow, Justin B. Echouffo-Tcheugui

“…Abstract Aims This short communication aims to assess the associations of body mass index (BMI) with key functional parameters, including exercise tolerance and functional status, among individuals with chronic heart failure. …”
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Alterations in static and dynamic functional network connectivity in subcortical vascular cognitive impairment by Haixia Mao, Yachen Shi, Qianqian Gao, Min Xu, Xiaoyun Hu, Feng Wang, Xiangming Fang

“…In the dFNC analysis, brain functional activity was grouped into four highly structured functional connection states. …”
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Structural and Functional Correlations in Patients with Advanced Stages of Primary Open-Angle Glaucoma by V. I. Kotelin, S. Yu. Petrov, A. N. Zhuravleva, M. V. Zueva, I. V. Tsapenko

“…In the study of morphological-functional relationships, the most significant correlations were revealed for the parameters of S-PERG. …”
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Normal Parathyroid Function with Decreased Bone Mineral Density in Treated Celiac Disease by Bernard Lemieux, Michel Boivin, Jean-Hugues Brossard, Raymond Lepage, Daniel Picard, Louise Rousseau, Pierre D’Amour

“…Parathyroid function results were also found to be similar in both groups. …”
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Impact of vitamin C deficiency on imaging patterns and ventilatory function in pulmonary tuberculosis by Ramona Cioboata, Ramona Cioboata, Mara Amalia Balteanu, Ovidiu Mircea Zlatian, Silviu Gabriel Vlasceanu, Mircea Vasile Popescu Driga, Denisa Maria Mitroi, Oana Maria Catana, Cezar Ionut Buciu, Georgiana Camen, Adina Andreea Mirea

“…Pulmonary function tests showed greater impairment in the low vitamin C group. …”
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The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes by Xiaoyu Zeng, Ying Lv, Zhongxiu Gu, Zhe Jia, Chen Zhang, Xiaoxiao Lu, Chenchen Chu, Yichen Gao, Yu Nie, Yanxia Wang, Yan Zhang, Shaozhen Zhao

“…Diabetic duration is an important factor that affects functions of the lacrimal functional unit in patients with Type II diabetes. …”
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Impact of COVID-19 Vaccination on Cardiac Function and Survival in Maintenance Hemodialysis Patients by Xiao Tu, Tingfei He, Bing Xu, Jiazhen Yin, Fangyu Yi, Ye Li, Jinchi Gao, Peng Bi, Wanyue Xu, Rihong Hu, Lidan Hu, Yayu Li

“…We compared the pre- and post-infection changes in heart function (echocardiographic parameters) and BNP levels between the two groups and assessed their association with the survival rates. …”
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