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1701
Effect of allopurinol on renal function in chronic kidney disease patients with asymptomatic hyperuricemia
Published 2017-01-01“…Objective To investigate the effect of allopurinol treatment on renal function in chronic kidney disease(CKD) patients with asymptomatic hyperuricemia.Methods Select the patients whom diagnosed CKD 2~3a phase with asymptomatic hyperuricemia from February 2014 to February2015 in nephrology department of yangzhou NO.1 people’s hospital.All patients were randomly divided into allopurinol treatmenl group and control group.Both groups treated with low salt,low fat,low protein and low purine diet,control blood pressure and blood glucose.Allopurinol treatment group received allopurinol 200 mg per day,the control group was not given uric acid lowering treatment One year after the treatment,observing two groups of eGFR,albuminuria and blood pressure in patients.Results In allopurinol treatment group,3 patients withdrawal due to rash,the incidence rate is7.14%.Allopurinol treatment significantly lower blood uric acid levels after 1 year later(515.28 ±114.13 vs 280.21 ± 72.58,P<0.01),the eGFR has no obvious change before and after the treatment(73.46 ± 18.38 vs 70.37 ± 20.11,P>0.05),while control group’s blood uric acid higher(487.02 ±78.57 vs 545.43 ± 89.56,P<0.05)and eGFR decline dramatically in a year later(70.43 ± 20.65 vs64.21 ± 17.42,P<0.05).In allopurinol treatment group,the level of proteinuria decreased slightly(0.62 ± 0.43 vs 0.48 ± 0.12,P>0.05),but there was no statistical significance(P>0.05),in the control group,albuminuria have no difference before and after treatment(0.60 ± 0.47 vs 0.64 ± 0.37,P>0.05).Systolic blood pressure(155.44±12.12 vs 125.21 ± 10.08,P<0.05;157.42 ± 14.12 vs128.45 ± 9.64,P<0.05) and diastolic blood pressure(88.56 ± 10.21 vs 80.45 ± 9.23,P<0.05;86.45 ± 11.56 vs 82.27 ± 6.25,P<0.05) were significantly lower than before after treatment in both groups,but there was no statistical difference between the two groups(P>0.05).Conclusions Allopurinol slowed the decline of eGFR in CKD 2~3a phase with asymptomatic hyperuricemia.…”
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1702
Kidney transplantation and evolution of parathyroid function: results of a single-center study
Published 2025-06-01“…The graft function was similar in the patients of all groups throughout the year. …”
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1703
FUNCTIONAL ABILITY AND QUALITY OF LIFE IN PATIENTS WITH RHEUMATOID ARTHRITIS RECEIVING TOCILIZUMAB THERAPY
Published 2014-02-01“…To study QoL and the functional status (FS) of Russian RA patients receiving tocilizumab (TCZ).Material and Methods. …”
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1704
Functional Properties of CD8+ Lymphocytes in Patients with Pleural Plaque and Malignant Mesothelioma
Published 2014-01-01“…The percentage of CD3+CD8+ cells in PBMCs did not differ among the three groups, although the total numbers of PBMCs of the PL and MM groups were lower than those of the healthy volunteers (HV). …”
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1705
Serum NT-proBNP levels as a marker for cardiopulmonary function in preeclampsia
Published 2020-08-01“…The PPE group had significantly higher serum NT-proBNP levels and lower LVEF than the NPE group. …”
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1706
Interaction of Dissolved Oxygen and Feed Fat Levels on Physiological Functions of Nile Tilapia
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1707
Analysis Effect of Nutrition Intake on Lung Function of Active Smoker and Non Smoker
Published 2018-11-01“…Data from 63 respondents in each group showed significant differences in nutrition intake and lung function (%FVC dan %FEV1) (p=0,001) in both groups. …”
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1708
Beta-adrenoЬlockers in patients with chronic heart failure and chronic obstructive pulmonary disease
Published 2008-12-01“…All patients underwent clinical examination, CHF FC assessment, echocardiography, 24-hour electrocardiography monitoring, renal function, lung function (LF), and quality of life assessment. …”
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1709
Enriched rehabilitation on brain functional connectivity in patients with post-stroke cognitive impairment
Published 2025-01-01“…ObjectiveThis study aims to observe the effect of enrichment rehabilitation (ER) on cognitive function in post-stroke patients and to clarify its underlying mechanism.MethodsForty patients with post-stroke cognitive impairment (PSCI) meeting the inclusion criteria were randomly assigned to two groups: conventional medical rehabilitation (CM group) and ER intervention (ER group). …”
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1710
Tranthoracic ultrasound for assessment of pulmonary function: a novel cross section study
Published 2025-04-01“…This study aims to correlate the dynamic respiratory motion of the lung during transthoracic ultrasonography with some parameters of ventilatory pulmonary function tests. Patients and methods It was carried on 42 persons classified into three groups: control group, obstructive group, and restrictive group – measurement of lung expansion parameters by an ultrasonography movie during breathing. …”
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1711
Normocalcemia and Normal Thyroid Function in a Severe Vitamin D–Deficient Population
Published 2025-07-01“…Background: Vitamin D has several physiological functions besides its well-known role in the hemostasis of calcium. …”
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1712
fMRI Study on the Functional Connectivity of Nucleus Accumbens in Patients with Knee Osteoarthritis
Published 2020-02-01“…Objective:To explore the underlying mechanism of pain syndrome in patients with knee osteoarthritis (KOA) via comparing the resting state functional connectivity (rs-FC) group difference of nucleus accumbens (NAc) between patients with KOA and healthy controls.Methods:A total of 16 KOA patients were enrolled as the KOA group, and 16 healthy controls were enrolled as the healthy control group. …”
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1713
Comparative Clinical and Functional Results of Microfracture and Mosaicoplasty in Medial Talus Osteochondral Lesions
Published 2024-09-01“…AOFAS scores improved significantly in both groups and the mosaicoplasty group had better functional results at 12 months (p=0.069). …”
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1714
Longitudinal Analysis of Honey Bee Colony Health as a Function of Pesticide Exposure
Published 2024-10-01“…This fractional change in population was evaluated as a function of pesticide load per pallet for each of the 37 pesticide chemicals detected, grouping pallets by beekeeper. …”
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1715
Enhancing the Functional Biodiversity of Ground-Dwelling Arthropods with Henbit (Lamium amplexicaule) Conservation
Published 2025-02-01“…In European countries, considerable research has focused on the conservation and improvement of biodiversity of functional groups which are useful organisms in agricultural lands. …”
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1716
Effect of Saengmaeksan on Fatigue, Liver Function, and Immunity Combined with High-Intensity Training
Published 2023-01-01“…ΔIgG, and ΔIgA vs. ΔIgG in the SMS group. These findings demonstrate that SMS intake can reduce ammonia, AST, ALT, and IgM levels, while causing an increase in IgA, which has a positive effect on fatigue reduction, liver function, and immunoglobulins in a high-intensity training or related environment.…”
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1717
Myocardial functional status in patients with arterial hypertension and hyperaldosteronism: orthogonal electrocardiography assessment
Published 2006-04-01“…To study orthogonal electrocardiography (ECG) parameters among arterial hypertension (AH) patients, in regard to renin-angiotensin-aldosterone system (RAAS) functional status. Material and methods. The study included 41 AH patients, mean age 45±2.8 years, and control group of 41 healthy individuals, mean age 41±7 years. …”
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1718
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
Published 2025-01-01“…However, their presence and functional role in non-model organisms is poorly understood. …”
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1719
Effects of acupuncture versus moxibustion on functional dyspepsia: a randomized clinical trial
Published 2025-08-01“…Abstract Background Functional dyspepsia (FD) is a prevalent gastrointestinal disorder, despite its high prevalence and impact on quality of life, effective treatments are limited. …”
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1720
Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure
Published 2009-01-01“…To study the influences of transient high intraocular pressure(IOP) during LASIK on retinal functions and ultrastructure. Methods. Thirty-two New Zealand white rabbits were randomly divided into normal control, experimental control, negative suction 20 s and negative suction 3 min groups. …”
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