Metabolic Markers Demonstrate the Heterogeneity of Walking Ability in Non-Disabled Community-Dwelling Older Adults by Shanshan Yao, Ziling Mao, Megan M. Marron, Eleanor M. Simonsick, Venkatesh L. Murthy, Ravi V. Shah, Anne B. Newman

“…A self-reported walking ability index (WAI) covering the difficulty and ease of walking captures a broader spectrum of walking ability in healthy older persons. …”
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Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation by Aishwarya Gondane, Harri M. Itkonen

“…Results We show that OGT / OGA inhibition reciprocally affect protein recruitment to RNA Pol II, and appropriate O-GlcNAcylation levels are required for optimal function of the RNA Pol II complex. These paradoxical effects are explained through IPA, because despite being prematurely poly-adenylated, these mRNAs are scored as mature in SLAM-seq. …”
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Multi-Objective Automated Machine Learning for Inversion of Mesoscopic Parameters in Discrete Element Contact Models by Xu Ao, Shengpeng Hao, Yuyu Zhang, Wenyu Xu

“…The developed AutoML model, comprising two hidden layers of 256 and 32 neurons with ReLU activation function, achieved coefficients of determination (<i>R</i>²) of 0.992, 0.710, and 0.521 for <i>E</i>, <i>k_s</i>/<i>k_n</i>, and <i>E_d</i>, respectively, demonstrating acceptable predictive accuracy and generalizability. …”
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Slow walking speed and health-related exit from employment among older workers over 5 years of follow-up: evidence from the Health and Employment After Fifty (HEAF) cohort study by Karen Walker-Bone, Holly E Syddall, Stefania D'Angelo, Elena Zaballa, G Ntani, Gregorio Bevilacqua

“…If workers at risk of mismatch of demand and capability could be identified early, there would be opportunities for intervention for health or lifestyle and/or re-training or redeployment.Objective To investigate whether self-reported walking speed (a good measure of function in elderly people) predicted health-related job loss (HRJL) longitudinally over 5 years of follow-up among middle-aged workers.Design Data came from the Health and Employment After Fifty (HEAF) prospective cohort study of middle-aged people (aged 50–64 years) in UK.Setting General population survey (sampling frame was 24 General Practice registers).Participants The cohort included 8134 people recruited in 2013–2014. …”
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Targeted therapy of bronchial asthma in children and adolescents: А narrative review by M. S. Matevosova, L. I. Agapitov, I. A. Averina, I. V. Sokolova, S. V. Zotova, R. A. Chernigovskiy

“…According to recent clinical studies among children and adolescents, biologicals to varying degrees can affect symptom control, lung function, frequency of exacerbations, requests for emergency medical care and hospitalizations, as well as reducing the dosages of glucocorticosteroids and beta-2-agonists used.Conclusion. …”
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Metastatic Adamantinoma of Fibula to the Lungs: A Rare Case Report by Knaj D, Ahmad G, Alshehabi Z, Ahmad IY

“…During treatment (after 2 cycles) the tumor showed progressive growth, resulting in decreased function of the affected limb. She was referred to the surgical department where the appropriate surgical amputation was performed. …”
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Operative Technique: Proximal Femur Allograft Reconstruction and Subtalar Fusion after Total Calcanectomy for a Large Giant Cell Tumor of the Calcaneus by Israel C Manuel, Ilian Dominiq D Eusebio, Emilleo A Dacanay, Bernardino B Alpuerto II

“…We decided to do salvage surgery for the patient and restore as much function as we can. We used the proximal femur allograft as its size and shape are almost the same as with the contralateral calcaneus. …”
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Nanostructure-controlled Cu-doped MnO2 for ozone synergistic catalytic disinfection by JianGuo Huang, Rashid Khan, Chunhui Zhai, Xianting Ding, Li-Sha Zhang, Jin-Ming Wu, Zhizhen Ye

“…Existing disinfection techniques commonly suffer from secondary pollution and difficulty in achieving continuous disinfection while ensuring safety and effectiveness, particularly in crowded environments. …”
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Cross-cultural research on cognitive development in infancy and early childhood: an overview of methods and research by Hacène SAADI

“…Studies of infants' attention and perception, object permanence and cognitive functioning, in general, in early childhood are discussed in relation to theoretical and methodological backgrounds (Piagetian studies, psychometric tests). …”
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Methodological quality of multivariate prognostic models for intracranial haemorrhages in intensive care units: a systematic review by Denis Frasca, Fanny Feuillet, Maxime Leger, Raphaël Cinotti, Yohann Foucher, Jeanne Simon-Pimmel, Laetitia Bodet-Contentin, Etienne Dantan

“…Objectives Patients with severe spontaneous intracranial haemorrhages, managed in intensive care units, face ethical issues regarding the difficulty of anticipating their recovery. Prognostic tools help clinicians in counselling patients and relatives and guide therapeutic decisions. …”
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First Experience of Multifocal and Toric Extended Depth of Focus Intraocular Lenses Implantation (Short-Term Analysis) by К. B. Pershin, N. F. Pashinova, А. Yu. Tsygankov, E. A. Antonov

“…Aim. Analysis of the functional results of new IOL with an extended depth of focus implantation a in the short-term (6 months) follow-up period.Patients and methods. …”
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Effects of Workplace-Related Factors on the Prevalence of Fibromyalgia among Israeli Kindergarten Teachers by Yafa Buskila, Tamar Chen-Levi, Dan Buskila, Giris Jacob, Jacob J. Ablin

“…Healthcare professionals treating individuals engaged in this occupation should be vigilant for the occurrence of symptoms that are clinically associated with FMS and overlapping functional disorders.…”
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FEATURES OF ETIOLOGY AND PATHOGENESIS OF DISORDERS OF TEMPOROMANDIBULAR JOINT, COMPLICATED BY DYSFUNCTION OF MASTICATORY MUSCLES by I.V. Yatsenko, D.S. Avetikov, V.M. Havrylyev, O.S. Ivanytska, N.A. Sokolova, I.V. Boiko

“… Unstable relationships of anatomical structures of temporomandibular joint (TMJ) which lead to its functional impairment is one of poorly studied problems in surgical dentistry. …”
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The association between multimorbidity and mobility disability-free life expectancy in adults aged 85 years and over: A modelling study in the Newcastle 85+ cohort. by Laurie E Davies, Stewart W Mercer, Katie Brittain, Carol Jagger, Louise Robinson, Andrew Kingston

“…<h4>Background</h4>Mobility disability is predictive of further functional decline and can itself compromise older people's capacity (and preference) to live independently. …”
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Postural Muscle Dyscoordination in Children With Cerebral Palsy by Jolanda C. van der Heide, Mijna Hadders-Algra

“…Until now, three children with CP functioning at GMFCS (Gross Motor Function Classification System) level V have been documented. …”
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Vibration Antiresonance Design for a Spacecraft Multifunctional Structure by Dong-Xu Li, Wang Liu, Dong Hao

“…This method can solve the structural vibration control problem under the function constraints of load bearing and energy supplying and will expand the performance of spacecraft functional modules.…”
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Case Report: A complex congenital bilateral multidirectional glenohumeral hyperlaxity with instability: surgical, anatomical, and forensic insights by Marco Capuzzo, Marco Capuzzo, Fernando Henrique Mizuno, Gaetano Maci, Luca Carboni, Aron Emmi, Veronica Macchi, Raffaele De Caro, Andrea Porzionato, Rafael Boscolo-Berto

“…At the one-year follow-up after the second surgery, the patient demonstrated substantial improvements in shoulder stability and functional outcomes. The Constant Shoulder Score (CSS) improved from 53 to 77 for both shoulders, indicating a 45.3% improvement and progression from “Moderate” to “Good” function. …”
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How to Make the Physical Parameters Small by Sergey G. Rubin

“…On the other hand, the discreteness of the energy levels of compact extra dimensions complicates the analysis. This difficulty can be overcome with the truncated Green functions.…”
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Morphosyntactic production and processing skills in relation to age effects and lexical-phonological levels among children with cochlear implants and typically hearing peers: a foc... by Sophie Fagniart, Sophie Fagniart, Brigitte Charlier, Brigitte Charlier, Véronique Delvaux, Véronique Delvaux, Véronique Delvaux, Bernard Georges Harmegnies, Bernard Georges Harmegnies, Bernard Georges Harmegnies, Anne Huberlant, Myriam Piccaluga, Myriam Piccaluga, Kathy Huet, Kathy Huet

“…Despite this, CI users showed distinct patterns of function word use, with fewer complex forms and more frequent errors, likely reflecting the perceptual challenges linked to CI. …”
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La terre des aînés : représentations du sol dans le système à maison pyrénéen by Claude Mercier

“…The polysemy of this term, far from constituting a difficulty, enabled us to explore several levels of observation which enlightened different aspects of the social functioning of the Pyrenean house-centred system to which constitutes the frame of this research. …”
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