Showing 3,221 - 3,231 results of 3,231 for search '(functional OR function) difficulty', query time: 0.21s Refine Results
  1. 3221

    SUNLAND: a randomized, double-blinded phase II GERCOR trial of sunitinib versus placebo and lanreotide in patients with advanced progressive midgut neuroendocrine tumors by Pascal Hammel, Denis Smith, Pauline Afchain, Sophie Dominguez-Tinajero, Jean-François Seitz, Astrid Lievre, Eric Van Cutsem, Eric Assenat, Frédéric Di Fiore, Marc Peeters, Iradj Sobhani, Eric Raymond, Emilie Charton, Dewi Vernerey, Louis De Mestier, Catherine Lombard-Bohas

    Published 2024-11-01
    “…Baseline health-related quality of life level was similar between treatment arms, except for physical and emotional functioning which were higher ( p  = 0.089) and lower ( p  = 0.023) in the sunitinib arm, respectively. …”
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  2. 3222

    Shortening duration of untreated illness in young people with first episode eating disorders: protocol of a randomised controlled feasibility trial of a smartphone friendly multi-m... by Luiza Grycuk, Dina Monssen, Molly R. Davies, Helen Sharpe, Karina L. Allen, Vibhore Prasad, Rachel Potterton, Priya Popat, Victoria A. Mountford, Sheryllin McNeil, Vanessa Lawrence, Nina Grant, Kimberley A. Goldsmith, Danielle Glennon, Sarah Byford, Amy Brown, Ulrike Schmidt

    Published 2025-02-01
    “…Outcomes will include motivation and readiness to change, attitudes and intentions towards help-seeking, ED symptoms, mood and social functioning, and health-related quality of life. Additionally, we will carry out a qualitative evaluation of participants’ views of the intervention and study design. …”
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  3. 3223

    History and development direction of iterative upgrading of deep coalbed methane reservoir reconstruction technology:Taking the Daji Block in the eastern margin of the Ordos Basin... by Fengyin XU, Huaibin ZHEN, Shuguang LI, Feng WANG, Lei ZHANG, Yubin WANG, Weichu YU, Weiping ZHU, Borui XU, Yun YANG, Haifeng ZHAO, Kunsen BAI

    Published 2025-03-01
    “…Practical application of finely tailored fracturing designs based on geological characteristics has yielded remarkable results.However, the paper identifies five key challenges and areas for improvement in deep coal reservoir stimulation: High water consumption and difficulties in managing flowback fluids during ultra-large-scale fracturing; The need for breakthroughs in intelligent fracturing technologies; Immaturity of collaborative fracturing methods; The urgent requirement to establish fracturing technology systems for deep, medium-to-low-rank coal seams; Incomplete functionality of fracturing fluids.To address these challenges, six development directions are proposed:① Advancing water-reducing fracturing techniques; ② Conducting research on fishbone horizontal wells combined with matrix acidizing for large-scale water-reduction and production enhancement; ③ Expanding the application of artificial intelligence in intelligent fracturing and post-fracturing evaluation; ④ Developing and implementing collaborative fracturing techniques to optimize well-to-fracture network integration; ⑤ Strengthening research and development and application of stimulation technologies for deep, medium-to-low-rank coal reservoirs; ⑥ Innovating new fracturing materials to further reduce costs, improve efficiency, and enhance recovery rates for deep CBM.…”
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  4. 3224

    Penerapan Importance Performance Analysis (IPA) pada Evaluasi Keberlanjutan Penggunaan e-filing untuk Pelaporan Pajak Perorangan by Imelda Saluza, Dewi Sartika

    Published 2022-02-01
    “…Some of these indicators include Understandability (clarity of information provided by e-filing), Contact (contact that can be contacted), Functionality (quality improvement and tax quality), Ease of Use (e-filing is difficult to learn), Usefulness (time saving reporting), Service Quality, Efficiency (accessing e-filing with other gadgets), Fulfillment (difficulties in meeting the needs of the reporter). …”
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  5. 3225

    Characteristics of the Epidemiological Situation in Patients with Tuberculosis of Various Age Groups Based on the Numerical Criteria of Selective Rating with the Help of the Comput... by Ilnуtskуy G.

    Published 2013-12-01
    “…The results were processed with the use of the statistical and mathematical functions of the MS Excel, parametric and nonparametric, for the establishing of the correlational relation assessing the dynamics of epidemiological parameters. …”
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  6. 3226

    Inclusión educativa de los estudiantes con discapacidad: un análisis de la percepción del profesorado (Educational inclusion of students with disabilities: an analysis of teachers'... by Lucía Pérez Vera, Susana Sánchez Herrera, María José Rabazo Méndez, María Jesús Fernández Sánchez

    Published 2024-01-01
    “…The results show that the majority of teachers affirm that the center in which they carry out their functions attends students with special educational needs and that curricular adaptations are the means by which these students receive regular educational support. …”
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  7. 3227

    A digital intervention to improve mental health and interpersonal resilience for young people who have experienced online sexual abuse: the i-Minds non-randomised feasibility clini... by Sandra Bucci, Filippo Varese, Ethel Quayle, Kim Cartwright, Amanda Larkin, Cindy Chan, Prathiba Chitsabesan, Victoria Green, William Hewins, Matthew Machin, Alice Newton, Erica Niebauer, John Norrie, Gillian Radford, Cathy Richards, Marina Sandys, Victoria Selby, Sara Shafi, Jennifer Ward, Pauline Whelan, Matthias Schwannauer

    Published 2025-07-01
    “…Quantitative and qualitative data showed that the i-Minds app was safe, acceptable and associated with promising signals of efficacy on valuable outcomes post treatment, including technology-assisted-sexual-abuse-related post-traumatic symptoms, resilience, internalising symptoms and reflective functioning. Most participants accessed or completed app modules. …”
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  8. 3228

    Didgital-art цінних паперів by Oleh Kardash, Viktor Chelombitko

    Published 2021-12-01
    “…The regularities of decoration are described — it has protective and aesthetic functions, which are realized by graphic design procedures. …”
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  9. 3229

    Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

    Published 2024-01-01
    “…On the other hand, in recent years, researchers' interest in the concept of "ecosystem" has been greatly expanded, and many researches have been conducted on what the ecosystem is and how it functions (Xi and Wang, 2021). The concept of "innovation ecosystem" has been considered since the mid-2000s as a framework for business development and the emergence of new industries. …”
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  10. 3230

    Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

    Published 2023-08-01
    “…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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  11. 3231

    Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

    Published 2024-12-01
    “…Outcome measures were recorded at baseline, 3 and 6 months (primary end point) to track changes in pain and functioning using the Short Form questionnaire-36 items physical component summary (SF-36-PCS) primary outcome measure, and were compared across the care models. …”
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