Complex Large-Deformation Multimodality Image Registration Network for Image-Guided Radiotherapy of Cervical Cancer by Ping Jiang, Sijia Wu, Wenjian Qin, Yaoqin Xie

“…On the basis of deep learning, bistructural morphology is added to the model to train the pelvic area registration evaluator, and the model can obtain parameters covering large deformation for loss function. The model was verified by the actual clinical data of cervical cancer patients. …”
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Parents' Distress and Demands for Children With Cancer‐Related Cognitive Impairment in Western China: A Qualitative Study by Tao Liu, LiFang Xu, Yuqing Shen, Zefang Chen, Juan Yao, Lin Mo

“…Results Three categories and 11 subcategories were obtained from the data analysis, including diverse levels of cognitive impairment in children (speech communication difficulties, impaired executive function, attention deficit, and intellectual disability), persistent negative emotions (anxiety and worry, complaints and resentment, negative avoidance and positive experiences after psychological adjustment), multiple needs (need for disease information, need for professional management, and an urgent need for more external support). …”
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Quantitative Methods of Selecting a Tool for Project Management in the Financial Sector by D. A. Vlasov, P. A. Karasev, A. V. Sinchukov

“…The formalized assessment of the functionality of the pre-selected tools made it possible to justify the choice of the most preferred alternative. …”
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Flexible physical sensors based on membranes: from design to application by Liwei Lin, Changqing Wu, Youfeng Cui, Minghao Pan, Ning Fang, Man Zhou, Yuzhe Zhang, Wang Zhang, Zhongyu Li, Ziyao Zhou, Yuanzhe Piao, Sun-Ha Paek

“…The first section of this review discusses membrane substrates and functional materials, summarizing the development of flexible physical sensors. …”
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Autonomic Responses to Emotional Stimuli in Children Affected by Facial Palsy: The Case of Moebius Syndrome by Ylenia Nicolini, Barbara Manini, Elisa De Stefani, Gino Coudé, Daniela Cardone, Anna Barbot, Chiara Bertolini, Cecilia Zannoni, Mauro Belluardo, Andrea Zangrandi, Bernardo Bianchi, Arcangelo Merla, Pier Francesco Ferrari

“…We therefore assessed Moebius children’s autonomic response to emotional stimuli (video cartoons) by means of functional infrared thermal (fIRT) imaging. Patients showed weaker temperature changes compared to controls, suggesting impaired autonomic activity. …”
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Collagen I Microfiber Promotes Brain Capillary Network Formation in Three–Dimensional Blood–Brain Barrier Microphysiological Systems by Kimiko Nakayama-Kitamura, Yukari Shigemoto-Mogami, Marie Piantino, Yasuhiro Naka, Asuka Yamada, Shiro Kitano, Tomomi Furihata, Michiya Matsusaki, Kaoru Sato

“…Moreover, BBB functional proteins show species differences; therefore, humanized in vitro BBB models are urgently needed to improve the predictability of preclinical studies. …”
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Bone scaffolds-based localized drugs delivery for osteosarcoma: current status and future perspective by Wenqing Liang, Hengguo Long, Hongwei Zhang, Juqin Bai, Bo Jiang, Jiangwei Wang, Lifeng Fu, Wenyi Ming, Jiayi Zhao, Bin Zeng

“…The discussion also includes difficulties and perspectives regarding the use of scaffold-based DDSs. …”
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Experience summary of a case of resetting the injection seat with flipping technique in an infusion port (1例输液港注射座翻转手法复位经验总结) by SUN Mengru (孙梦茹), GUO Yanping (郭燕平), GONG Yuan (龚媛)

“…Intervention measures including nutrition support, psychological care, health education and maintenance of infusion port were taken, and the infusion port function was normal after manual reduction. There were no further complications in the patient's subsequent treatment. …”
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Quality of life in patients with non-small cell lung cancer by Šarac Sanja, Milić Rade, Vasiljević Mira, Šarac Momir

“…There were no changes in the global health status score between the baseline, the 2nd and the 4th cycle of chemotherapy (42.78 ± 15.76, 45.56 ± 17.59, 48.20 ± 19.24, respectively; p = 0.1). Social function score, symptom scores: nausea and vomiting, pain, appetite loss, constipation, diarrhea and financial difficulties score differed significantly among chemotherapy cycles, indicating improved or worsened the QoL. …”
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Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later. by Adam Attaheri, Áine Ní Choisdealbha, Sinead Rocha, Perrine Brusini, Giovanni M Di Liberto, Natasha Mead, Helen Olawole-Scott, Panagiotis Boutris, Samuel Gibbon, Isabel Williams, Christina Grey, Maria Alfaro E Oliveira, Carmel Brough, Sheila Flanagan, Usha Goswami

“…This phenomenon has been measured in both children and adults, reflecting speech understanding by adults as well as cognitive functions such as attention and prediction. Furthermore, atypical low-frequency cortical tracking of speech is found in children with phonological difficulties (developmental dyslexia). …”
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Adaptation to Long-Term Home Non-Invasive Ventilation for People with Chronic Hypercapnic Respiratory Failure: A Qualitative Study by Nur Zahrah Yuko Yacob Hussain, Norasyikin Hassan, Hang Siang Wong, Yingjuan Mok, Piyanee Klainin-Yobas

“…<b>Background/Objectives:</b> Home non-invasive ventilation use is the primary treatment for improving respiratory function in people with chronic hypercapnic respiratory failure. …”
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Research Themes in KAT6A Syndrome: A Scoping Review by Tanya Tripathi, Miya St John, Jordan Wright, Natacha Esber, David J. Amor

“…Data were synthesised into six themes: (1) the genotype and phenotype map, revealing a broad phenotypic spectrum with common features like ID, absent speech, and craniofacial dysmorphism, as well as rare features such as severe aplastic anaemia and pancraniosynostosis; (2) the neurodevelopmental profile, detailing communication deficits, sleep disturbances, and impaired adaptive functioning; (3) the epigenetic and developmental roles of <i>KAT6A</i>, highlighting its critical function in histone acetylation, chromatin remodelling, and gene regulation; (4) molecular biomarkers, identifying distinct DNA methylation episignatures and dysregulated cellular pathways; (5) drug discovery, with preliminary studies suggesting that pantothenate and L-carnitine may mitigate mitochondrial dysfunction and histone acetylation deficits, while RSPO2 overexpression reverses cognitive impairment in animal models; (6) phenotypic overlap with Rett syndrome and <i>KAT6B</i>-related disorders. …”
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Exploring the Impact of the COVID-19 pandemic on depression in middle-aged and older Canadians with diabetes: Insights on incidence, recurrence, and risk factors from the Canadian... by ZhiDi Deng, B.Sc, PharmD, Grace Li, PhD, Maria E. Rowsell, MSW, RSW, Dorina Cadar, Esme Fuller-Thomson, PhD

“…Factors associated with increased risk of incident and recurrent depression during the pandemic among older adults with diabetes include being female, greater educational attainment, higher income/savings, functional limitations, loneliness/social isolation, chronic pain, family conflict, and difficulties accessing health care. …”
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Unraveling the complex genetic landscape of OTOF-related hearing loss: a deep dive into cryptic variants and haplotype phasing by Pei-Hsuan Lin, Cheng-Yu Tsai, Yu-Ting Chiang, Chang-Han Ho, Yue-Sheng Lu, Jacob Shu-Jui Hsu, Yen-Fu Cheng, Shih-Feng Tsai, Chuan-Jen Hsu, Pei-Lung Chen, Chen-Chi Wu

“…However, challenges remain in interpreting OTOF variants, including difficulties in confirming haplotype phasing using traditional short-read sequencing (SRS) due to the large gene size, the potential incomplete penetrance of certain variants, and difficulties in assessing variants at non-canonical splice sites. …”
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Experience in Using ^99mTc-Technephyt Esophageal Transit Scintigraphy for Assessing Pneumatic Dilation Outcome in Patients with Achalasia Cardia by R. A. Bashirov, A. I. Shelepova, L. E. Samoilenko, S. A. Ryzhkin, B. M. Sharafutdinov, A. F. Yusupova, L. F. Ziganshina, B. A. Magomedov, A. I. Kukushkin, V. Yu. Matveev, D. R. Bashirov

“…It is a physiological and safe procedure, which can be recommended in cases of difficulties in evaluating the esophageal function by X-ray, endoscopic and manometric methods or when their use is impossibile.…”
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Yo3RL-Net:A fusion of two-phase end-to-end deep net framework for hand detection and gesture recognition by Xiang Wu, Yuanhao Ma, Shijie Zhang, Tianfei Chen, He Jiang

“…Additionally, the Inner-CIoU loss function is replaced. These enhancements greatly improve the extraction of hand characteristics in video frames. …”
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Secondary Hip Osteoarthritis due to Neurofibroma Treated with Total Hip Replacement by Suksan Tangsataporn, Alireza Shakib, Paul R. Kuzyk, David J. Backstein, Allan E. Gross, Oleg A. Safir

“…One year after the surgery, the patient had excellent clinical function, hip stability, leg length equality and was satisfied with the outcome. …”
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Results of Cross-Sectional Study of the Opinion from Parents of Children with Clubfoot on Medical Care via Ponseti Method in Outpatient Center of Surgery, Traumatology and Orthoped... by Ilya V. Krestyashin, Aleksandr Yu. Razumovsky, Vladimir M. Krestyashin, Arina M. Chmykhova, Lyubov S. Zolotareva

“…Patients with clubfoot can have pain and functional disorders that lead to disability. Familiarity of obstetrician-gynecologists, general practitioners, surgeons with its early diagnosis and timely management may prevent disablement.Objective. …”
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Moderating role of positive aspects of caregiving in the relationship between caring burden and suicidal ideation in family caregivers of community-dwelling older adults with neuro... by Zhaohua Huo, Benjamin Hon-Kei Yip, Allen Ting-Chun Lee, Sheung-Tak Cheng, Wai Chi Chan, Ada Wai-Tung Fung, Suk Ling Ma, Calvin Pak-Wing Cheng, Frank Ho-Yin Lai, Samuel Yeung-Shan Wong, Linda Chiu-Wa Lam

“…Higher prevalence was observed among female carers, those with comorbid mood disorders, and those caring for individuals with high comorbidity or functional dependence. Psychological distress significantly mediated the relationship between caregiving burden and suicidal ideation (80.5%, p = 0.023). …”
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A novel reinforcement learning framework-based path planning algorithm for unmanned surface vehicle by Jianhui Mou, Bo Shi, Bo Wang, Chengcheng Yu, Yangwei Wang, Fusheng Zhong, Li Zheng, Jian Wang, Junjie Li

“…Second, a comprehensive reward function incorporating artificial potential field (APF) inspiration is designed to guide the USV to reach the target region. …”
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