CD45 and CD148 Are Critically Involved in Neutrophil Recruitment and Function During Inflammatory Arthritis in Mice by Jan-Niklas Heming, Andreas Margraf, Karolina Najder, Giulia Germena, Mathis Richter, Anika Cappenberg, Katharina Henke, Bernadette Bardel, Lena Schemmelmann, Marina Oguama, Pia Lindental, Wida Amini, Jacqueline Sobocik, Georg Schett, Gerhard Krönke, Helena Block, Jan Rossaint, Oliver Soehnlein, Alexander Zarbock

“…Furthermore, we could demonstrate that activation of Src family kinases in neutrophils is differentially regulated by CD45 and CD148 in a stimulus-dependent manner. Summarizing, our results suggest that CD45 is positively involved, while CD148 is positively and negatively involved in neutrophil recruitment and function during inflammatory arthritis.…”
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Nutritional supplement Youtianli regulates Treg function and gut immunity via SCFA-producing microbiota modulation by Hexiu Yuan, Yichun Xiao, Yubo Huang, Leming Huang

“…Fecal microbiota transplantation (FMT) demonstrated that immunoregulatory effects of YTL were microbiota-dependent. These findings suggest that YTL improves immune function by modulating gut microbiota and enhancing SCFA metabolism. …”
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Natural and sexual selection and functional roles influence colouration but not the amount of variation in butterfly wing colour patterns by Bhavya Dharmaraaj, Krushnamegh Kunte

“…Abstract Background Trait variation is shaped by functional roles of traits and the strength and direction of selection acting on the traits. …”
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Deformable detection transformers for domain adaptable ultrasound localization microscopy with robustness to point spread function variations by Sepideh K. Gharamaleki, Brandon Helfield, Hassan Rivaz

“…However, MB localization faces challenges due to dynamic point spread functions (PSFs) caused by harmonic and sub-harmonic emissions, as well as depth-dependent PSF variations in ultrasound imaging. …”
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The Impact of Combined Scapular Stabilization and Breathing Training on Pain and Respiratory Function in Individuals with Upper Cross Syndrome by Xin Yan, Tae-Ho Kim

“…After four weeks of exercise, changes in the pressure pain threshold (PPT), respiration function, and lower chest expansion (LCE) were measured again. …”
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A MATHEMATICAL APPROACH TO INVESTMENT WITH CHARGE ON BALANCE AND VOLUNTARY CONTRIBUTIONS UNDER WEIBULL MORTALITY FORCE FUNCTION by Edikan Edem Akpanibah, Peter Benneth, Ase Matthias Esabai

“…Also, the portfolio considers additional voluntary contributions (AVC) by members, tax on the stock market price, charge on balance (CB), and the mortality risk of the pension scheme members (PSM) modeled by the Weibull mortality force function.  Furthermore, an optimization problem is established from the extended Hamilton Jacobi Bellman (EHJB) equation using variational method. …”
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Dietary Exercise as a Novel Strategy for the Prevention and Treatment of Metabolic Syndrome: Effects on Skeletal Muscle Function by Wataru Aoi, Yuji Naito, Toshikazu Yoshikawa

“…Metabolic syndrome is associated with metabolic function in the skeletal muscle, a major consumer of nutrients. …”
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The Effect of 8 Weeks of Core Stability Training Program on Lumbar-Pelvic Function in Children with Autism Spectrum by Sarvin Salar, Hassan Daneshmandi

“…Core stabilization training was performed based on Jeffrey protocol for 8 weeks, 3 sessions per week individually in the experimental group. The lumbar-pelvic function was measured by step down test. After checking data normality by Kolmogorov-Smirnov test, data were analyzed by dependent and independent t tests. …”
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Formal and functional factors in classifier choice: Evidence from American Sign Language and Danish Sign Language by Engberg-Pedersen Elisabeth, Brentari Diane K., Davis Jeffery

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Functional recoding of Chlamydomonas reinhardtii thioredoxin type-h into photosynthetic type-f by switching selectivity determinants by Stéphane D. Lemaire, Gianluca Lombardi, Andrea Mancini, Alessandra Carbone, Alessandra Carbone, Julien Henri

“…Specialization of thioredoxin function is correlated to its selectivity towards a type-dependent repertoire of protein targets. …”
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Functionality and translation fidelity characterization of mRNA vaccines using platform based mass spectrometry detection by Alyssa Q. Stiving, Benjamin W. Roose, Christopher Tubbs, Mark Haverick, Ashley Gruber, Richard R. Rustandi, Jesse Kuiper, Matthew Schombs, Hillary Schuessler, Xuanwen Li

“…This workflow enabled evaluation of mRNA functionality under thermal stress and assessment of multivalent formulations with high sequence homology. …”
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Sustainable materials for novel food packaging based on alginate, methylcellulose and glycerol films functionalized with gallic acid by Francisco Javier Leyva-Jiménez, Carlos Abellán-Dieguez, Rodrigo Oliver-Simancas, Antonio M. Rodríguez-García, M. Elena Alañón

“…Moreover, the films functionalized with gallic acid displayed enhanced antioxidant properties in a concentration-dependent manner. …”
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SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae. by Mickaël Durand-Dubief, William Ryan Will, Edoardo Petrini, Delphine Theodorou, Rachael R Harris, Margaret R Crawford, Konrad Paszkiewicz, Felix Krueger, Rosa Maria Correra, Anna T Vetter, J Ross Miller, Nicholas A Kent, Patrick Varga-Weisz

“…Here we show that Fun30, a poorly understood SWI/SNF-like chromatin remodeling factor conserved in humans, promotes point centromere function through the formation of correct chromatin architecture at centromeres. …”
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Transcription of GABAA receptor subunits in circulating monocytes and association to emotional brain function in premenstrual dysphoric disorder by Louise Stiernman, Erika Comasco, Maja Johansson, Marie Bixo

“…We related mRNA subunit expression to serum levels of neurosteroids and to functional activation of the amygdala, a key brain region involved in emotion generation, measured using functional magnetic resonance imaging (fMRI). …”
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Cued Reactivation of Motor Learning during Sleep Leads to Overnight Changes in Functional Brain Activity and Connectivity. by James N Cousins, Wael El-Deredy, Laura M Parkes, Nora Hennies, Penelope A Lewis

“…We use functional magnetic resonance imaging (fMRI) to show a change in the neural representation of a motor memory after targeted reactivation in slow-wave sleep (SWS). …”
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Structure-Function Analysis of DipA, a Francisella tularensis Virulence Factor Required for Intracellular Replication. by Audrey Chong, Robert Child, Tara D Wehrly, Dedeke Rockx-Brouwer, Aiping Qin, Barbara J Mann, Jean Celli

“…DipA is a 353 amino acid protein with a Sec-dependent signal peptide, four Sel1-like repeats (SLR), and a C-terminal coiled-coil (CC) domain. …”
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THE STATE OF THE SIRS AND ENDOTHELIAL FUNCTION IN HYPERTENSIVE PATIENTS, STAGE II IN THE PROCESS OF ISCHEMIC HEART DISEASE DEVELOPING by I. M. Fushtey, V. A. Mochonyi, E. V. Sid’, N. F. Efimenko

“…In order to determine the concentration of immuno-inflammatory markers in the blood plasma, interleukin-1β (IL-1β), interleukin-10 (IL-10), high-sensitivity C-reactive protein (HS-CRP) and their relationship with endothelial function (according to end-point metabolites of nitric oxide and reactive hyperemia) a comprehensive study of 180 patients with stage II EH was conducted. …”
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Functional control of the technical condition method for aircraft control system sensors under complete parametric uncertainty by J. V. Bondarenko, E. Yu. Zybin

“…This leads to the need for the problem of aircraft flight dynamics modeling with a high level of uncertainties to be solved, which complicates the application of functional test methods and determines the necessity of excessive sensors hardware redundancy. …”
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Post translational modification regulation of transcription factors governing pancreatic β-cell identity and functional mass by Alicia Wong, Emilyn U. Alejandro

“…The development and maintenance of pancreatic β-cell identity, function, and adaptation to stress is governed, in part, by the spatiotemporal expression of transcription factors (TFs), whose activity is regulated by signal-dependent post-translational modifications (PTM). …”
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Bavachin enhances paclitaxel sensitivity in ovarian cancer cells through modulation of mitochondrial function and ER stress by Sang-Jin Lee, Kee K. Kim, Jin-Young Lee

“…Mechanistically, bavachin disrupted mitochondrial function by inducing membrane depolarization and calcium dysregulation, leading to comprehensive impairment of cellular bioenergetics including both oxidative phosphorylation and glycolysis. …”
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