Evaluating self-assistance during functional reach with a passive hydrostatic exoskeleton under artificial impairment by Julia Manczurowsky, Henry Mayne, David Nguyen, Meghan Kenney, John Peter Whitney, Christopher J. Hasson

“…Conclusions In this sample of adults with an artificial impairment, self-assistance using a passive hydrostatic exoskeleton accelerated motor performance improvements without creating a dependency on the assistance. If replicated in clinical populations, this approach may help promote upper-limb functional independence.…”
Get full text

Genome‐wide off‐rates reveal how DNA binding dynamics shape transcription factor function by Wim J de Jonge, Mariël Brok, Philip Lijnzaad, Patrick Kemmeren, Frank CP Holstege

“…Sites with different off‐rates are associated with different functional characteristics. This includes their transcriptional dependency on Abf1, nucleosome positioning and the size of the nucleosome‐free region, as well as the ability to roadblock RNA polymerase II for termination. …”
Get full text

Modular-Multi-Port-Converter-Based Battery Energy Storage System with Integrated Battery Management Functions by Bortecene Yildirim, Mohammed A. Elgendy, Andrew Smith, Mehmet C. Kulan, Bahadir Akbal

“…Modular converters offer an effective solution for battery energy storage systems (BESSs) by lowering battery pack voltage levels and enabling additional functionalities, such as state of charge (SoC) and state of health (SoH) balancing, temperature regulation, and improved system reliability. …”
Get full text

An attention-based loss function and synthetic minority oversampling technique for alleviating class imbalance in predicting diabetes by Santanu Roy, Reshma Rachel Cherish, Gifty Roy

“…(ii) A Swish activation function is deployed in the hidden layer of DB-Lite instead of Rectified Linear Unit (ReLU) to deal with the non-linear dependency of features with the final outcome. …”
Get full text

Transcranial brain-wide functional ultrasound and ultrasound localization microscopy in mice using multi-array probes by Mathis Vert, Ge Zhang, Adrien Bertolo, Nathalie Ialy-Radio, Sophie Pezet, Bruno Osmanski, Thomas Deffieux, Mohamed Nouhoum, Mickael Tanter

“…Our findings reveal a significant correlation between absolute cerebral blood volume (ΔCBV) increases and microbubble speed, indicating vessel-level dependency of the evoked response. However, the lack of correlation with relative CBV (rCBV) suggests that fUS cannot distinguish functional responses alterations across different arterial vascular compartments. …”
Get full text

Context specific effects of substrate composition on the taxonomic and functional diversity of macroinvertebrate communities in temperate lowland streams by Kate L. Mathers, Patrick D. Armitage, Matthew Hill, Melanie Bickerton, Morwenna Mckenzie, Isabel Pardo, David Tickner, Paul J. Wood

“…However, alpha diversity metrics and Local Contribution to Beta Diversity (LCBD) recorded among the different habitat units varied significantly across individual rivers, and the amount of variation explained by the habitat unit for taxonomic and functional composition demonstrated considerable differences suggesting strong context dependence. …”
Get full text

Prediction of Dynamic Characteristics of Thermocouples with Thin-Wire Sensing Elements by I. A. Safina, S. A. Artemyeva

“…Simplified relations in the form of hyperbolic functions with constant parameters and argument in the form of Vm2 ρm2 complex were obtained for airflowat different temperatures, pressures, and velocities.On the example of airflow, it is shown that the complex multi-parametric relation linking the expectedand known time constants of thermocouples can be simplified to a hyperbolic dependence, where the argument can be the Vm2 ρm2 complex. …”
Get full text

AN ANALYSIS OF ENGLISH REGISTER USED ON MAKEUP TUTORIAL CONTENTS IN INDIRA KALISTHA YOUTUBE CHANNEL by Almira Rahma Syastuti, Rahmaditya Khadifa Abdul Rozzaq Wijaya

“…In Sociolinguistics, register is a term in the specific lexical and grammatical selection used by speakres depending on the context and situation. This research focused on the types and the function of register used on makeup tutorial contents in Indira Kalistha YouTube Channel. …”
Get full text

Processing demands modulate the activities and functional connectivity patterns of the posterior (VWFA-1) and anterior (VWFA-2) VWFA by Aqian Li, Chuansheng Chen, Xiaoyan Wu, Yuan Feng, Jingyu Yang, Xiaoxue Feng, Rui Hu, Leilei Mei

“…To address these questions, the present study adopted two tasks varying in processing demands (i.e., verbal and non-verbal tasks), and used generalized psychophysiological interaction (gPPI) and dynamic causal modeling (DCM) analyses to explore the task-dependent functional connectivity patterns of the two subregions of the VWFA. …”
Get full text

The circadian regulation of sleep: impact of a functional ADA-polymorphism and its association to working memory improvements. by Carolin F Reichert, Micheline Maire, Virginie Gabel, Marcel Hofstetter, Antoine U Viola, Vitaliy Kolodyazhniy, Werner Strobel, Thomas Goetz, Valérie Bachmann, Hans-Peter Landolt, Christian Cajochen, Christina Schmidt

“…Twenty-four participants were genotyped regarding a functional polymorphism in adenosine deaminase (rs73598374, 12 G/A-, 12 G/G-allele carriers), previously associated with differences in sleep-wake regulation. …”
Get full text

Preventative Cancer Vaccine-Elicited Human Anti-MUC1 Antibodies Have Multiple Effector Functions by Michelle L. McKeague, Jason Lohmueller, Matthew T. Dracz, Najla Saadallah, Eric D. Ricci, Donella M. Beckwith, Ramya Ayyalasomayajula, Maré Cudic, Olivera J. Finn

“…Results: All three mAbs mediated antibody-dependent cytokine release (ADCR), antibody-dependent cellular cytotoxicity (ADCC), and antibody-dependent cellular phagocytosis (ADCP). …”
Get full text

Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling. by Lee M Wheldon, Bryan P Haines, Rajit Rajappa, Ivor Mason, Peter W Rigby, John K Heath

“…<h4>Conclusions</h4>This study shows that the phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR. …”
Get full text

CALIX[4]ARENE C-715 MODULATES MITOCHONDRIAL FUNCTIONING AND CONTRACTILE ACTIVITY OF UTERINE SMOOTH MUSCLE by I.S. Forys, O.V. Tsymbalyuk, R.V. Rodik, M.V. Rudnytska, H.V. Danylovych, YU.V. Danylovych

“…To elucidate the effects of calix[4]arene C-715 on the contractile activity of myometrial strips and the Ca2+-dependent functional activity of mitochondria. Materials and Methods. …”
Get full text

Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. by Nicolas Siaud, Maria A Barbera, Akinori Egashira, Isabel Lam, Nicole Christ, Katharina Schlacher, Bing Xia, Maria Jasin

“…Our results reveal functional redundancy within the BRCA2 protein and emphasize the plasticity of this large protein built for optimal HR function in mammalian cells. …”
Get full text

Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope by Michael V. Bick, Eduard Puig, David Beauparlant, Rebecca Nedellec, Iszac Burton, Keihvan Ardaghi, Thea R. Zalunardo, Raiza Bastidas, Xuduo Li, Javier Guenaga, Wen-Hsin Lee, Richard Wyatt, Wenwen Zhu, Max Crispin, Gabriel Ozorowski, Andrew B. Ward, Dennis R. Burton, Lars Hangartner

“…Summary: Antibody effector functions contribute to the immune response to pathogens and can influence the efficacy of antibodies as therapeutics. …”
Get full text

The characteristic of the engine qualities of the students of technical institute of III functional health group (special medical group) by L.N. Prosvirina, M.M. Kolokoltsev, M.A. Kolchanova, Miroslawa Cieslicka, Blazej Stankiewicz

“…Purpose : the study of the dynamics of engine qualities in the students of III functional health group (special medical group) dependent on age taking into account the frequency of occupations by physical culture for the correction of the program of their physical training. …”
Get full text

Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis by Jing Zhu, Ruize Xie, Qiaoying Ren, Jiaming Zhou, Chen Chen, Meng-Xi Xie, You Zhou, Yan Zhang, Ningjing Liu, Jinchao Wang, Zhengwei Zhang, Xipeng Liu, Wupeng Yan, Qingqiu Gong, Liang Dong, Jinwei Zhu, Fengping Wang, Zhiping Xie

“…This AArf interacted with Sec23, a COPII vesicle coat component, in a GTP-dependent manner. These findings suggest certain AArfs are membrane-associating molecular switches with the functional potential to initiate organelle biogenesis, and the evolution of a functional coat could be the next critical step towards establishing eukaryotic cell architecture.…”
Get full text

Message Framing Effects on Helping Behavior as a Function of Age in Early Childhood and School-Age Children by Heesun Chang, Hohyun Kim

“…This study determined the effects of message framing on helping behavior as a function of age in preschool and early school-age children. …”
Get full text

Hsp90 and cochaperones have two genetically distinct roles in regulating eEF2 function. by Melody D Fulton, Danielle J Yama, Ella Dahl, Jill L Johnson

“…Eukaryotic elongation factor 2 (eEF2) promotes GTP-dependent translocation of the ribosome during translation. eEF2 folding was recently shown to be dependent on Hsp90 as well as the cochaperones Hgh1, Cns1, and Cpr7. …”
Get full text

Structural myocardial changes in chronic heart failure of II functional class based on overweight and abdominal obesity by V. Z. Netyazhenko, P. P. Bidzilya

“…Research objective: to establish the structural changes of CHF of II functional class depending on the availability of overweight and abdominal type of obesity various degrees. …”
Get full text