Activation of the Rat P2X7 Receptor by Functionally Different ATP Activation Sites by Fritz Markwardt, Malte Berthold, Sanaria Hawro Yakoob, Günther Schmalzing

“…The 7-7-7 concatamer exhibited a biphasic ATP⁴⁻ concentration dependence, best fit by the sum of two Hill functions, confirming the existence of functionally distinct ATP⁴⁻ activation sites. …”
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IMPULSE OSCILLOMETRY FOR DIAGNOSIS OF EARLY CHANGES IN THE RESPIRATORY SYSTEM FUNCTIONAL STATE IN PATIENTS WITH MILD ASTHMA by N. M. Leontieva, I. V. Demko, E. A. Sobko, O. P. Ishchenko, I. A. Solov’yova

“…Currently, the analysis of respiratory function of lungs at suspicion of obstructive pulmonary diseases is recommended to start with spirometry as the most sensitive method of obstruction detection. …”
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SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions by Qiwei Jiang, Nana Zheng, Lang Bu, Xiaomei Zhang, Xiaoling Zhang, Yuanzhong Wu, Yaqing Su, Lei Wang, Xiaomin Zhang, Shancheng Ren, Xiangpeng Dai, Depei Wu, Wei Xie, Wenyi Wei, Yasheng Zhu, Jianping Guo

“…Conclusions Our results not only reveal a physiological regulation of PDK1 by E3 ligase SPOP, but also highlight the oncogenic roles of loss-of-function mutations of SPOP or gain-of-function mutations of PDK1 in tumorigenesis through activating the AKT kinase.…”
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IMMUNOLOGICAL PARAMETERS, FUNCTIONAL AND METABOLIC ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH BASAL CELL SKIN CARCINOMA by L. M. Kurtasova, G. A. Arutyunyan, E. A. Shkapova, A. E. Pobilat

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Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W by Bernardo A. Bustillos, Liam T. Cocker, Mathew A. Coban, Caleb A. Weber, Jenny M. Bredenberg, Paige K. Boneski, Joanna Siuda, Jaroslaw Slawek, Andreas Puschmann, Derek P. Narendra, Neill R. Graff-Radford, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross, Thomas R. Caulfield, Wolfdieter Springer, Fabienne C. Fiesel

“…The functional analysis was accompanied by structural investigation of PRKN p.R275W. …”
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NON-SPECIFIC CONGENITAL CONNECTIVE TISSUE DISORDERS AS AN INDEPENDENT PREDICTOR OF STRUCTURAL AND FUNCTIONAL ARTERIAL CHANGES by A. A. Semenkin, O. V. Drokina, G. I. Nechaeva, L. A. Zhivilova, A. B. Zhenatov

“…To assess the impact of non-specific congenital connective tissue disorders (CCTD) on the changes in arterial stiffness and endothelial function; to study the role of CCTD as an independent predictor of structural and functional arterial changes.Material and methods. …”
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The long-term correlates of developmental stress on whole-brain functional connectivity during emotion regulation by Seda Sacu, Andrea Hermann, Tobias Banaschewski, Martin F. Gerchen, Nathalie E. Holz

“…Our findings revealed distinct associations between stress exposure and task-specific functional connectivity, depending on the developmental timing of stress exposure. …”
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The interactions of non-functionalized polystyrene nanoparticles with human albumin and erythrocyte proteins: implications and potential consequences by Kamil Płuciennik, Mariusz Szabelski, Katarzyna Miłowska, Karol Ciepluch, Piotr Duchnowicz, Anita Krokosz, Paulina Sicińska, Bożena Bukowska

“…Abstract The aim of the study was to determine the concentration- and size-dependent effects of ~30 nm, ~45 nm and ~70 nm non-functionalized polystyrene nanoparticles (PS-NPs) on human serum albumin (HSA) and human erythrocyte proteins in vitro. . …”
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Functional state of the cardiorespiratory system after orthotopic heart transplantation with prolonged cold ischemia time by I. Yu. Loginova, O. V. Kamenskaya, A. V. Fomichev, D. V. Doronin, A. M. Chernyavskiy, V. V. Lomivorotov

“…All the parameters of pulmonary function tests did not differ significantly depending on cold ischemia duration. …”
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A systematic review and dose response meta analysis of Omega 3 supplementation on cognitive function by Hossein Shahinfar, Zahra Yazdian, Neda Asgari Avini, Kimia Torabinasab, Sakineh Shab-Bidar

“…Abstract The dose-dependent effects of omega-3 supplementation on cognitive function remain unclear. …”
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Protective Potential and Functional Role of Antibodies Against SARS-CoV-2 Nucleocapsid Protein by Alexandra Rak, Ekaterina Bazhenova, Polina Prokopenko, Victoria Matyushenko, Yana Orshanskaya, Konstantin V. Sivak, Arina Kostromitina, Larisa Rudenko, Irina Isakova-Sivak

“…The animals were infected with 10⁵ or 10⁴ TCID₅₀ of SARS-CoV-2 (B.1, Wuhan or BA.2.86.1.1.18, Omicron) 6 h after serum passive transfer, and protection was assessed by weight loss, clinical manifestation of disease, viral titers in the respiratory tract, as well as by the histopathological evaluation of lung tissues. The functional activity of anti-N(B.1) antibodies was evaluated by complement-dependent cytotoxicity (CDC) and antibody-dependent cytotoxicity (ADCC) assays. …”
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Free vibration analysis of functionally graded shell panels with various geometric shapes in thermal environment by Duong Thanh Huan, Tran Huu Quoc, Tran Minh Tu

“…Material properties are assumed to be temperature-dependent and graded in the thickness direction according to a power law function. …”
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The Strict Stability of Impulsive Differential Equations with a Caputo Fractional Derivative with Respect to Other Functions by Ravi P. Agarwal, Snezhana Hristova, Donal O’Regan

“…These sufficient conditions depend significantly on the type of impulsive function.…”
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Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome by Michael A Noble, J Scott Whittaker, Anil K Mangal, Cedric J Carter, Hugh J Freeman

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Changes in brain functional connectivity associated with transcutaneous auricular vagus nerve stimulation in healthy controls by Daniel A. Monti, Nancy Wintering, Faezeh Vedaei, Alicia Steinmetz, Feroze B. Mohamed, Andrew B. Newberg, Andrew B. Newberg

“…To evaluate the primary outcome of neurophysiological effects, all participants received blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) during the TaVNS on and off states.ResultsThe results demonstrated significant changes in functional connectivity during TaVNS that differed depending on the frequency of stimulation and which ear was stimulated. …”
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Assessment of dynamics of asynchronous drive by nonlinear transfer function. Correction of nonlinearity of asynchronous electric drive by A. A. Baldenkov, V. L. Kodkin, A. S. Anikin

“…For the first time, the nonlinearity of the mechanical characteristics of an asynchronous electric motor is taken into account in the transfer function of the torque former, which is expressed in dependence of this function on sliding (lag of the rotor speed of rotation of the speed of rotation of the stator magnetic field) and on the frequency of the voltage at the motor stator. …”
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Dynamics and Stabilization of Chaotic Monetary System Using Radial Basis Function Neural Network Control by Muhamad Deni Johansyah, Aceng Sambas, Fareh Hannachi, Seyed Mohamad Hamidzadeh, Volodymyr Rusyn, Monika Hidayanti, Bob Foster, Endang Rusyaman

“…The system demonstrates a variety of behaviors, including chaotic, periodic, and equilibrium states depending on parameter values. Additionally, we explore the multistability of the system and present a radial basis function neural network (RBFNN) controller design to stabilize the chaotic behavior. …”
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Environmental Noise Assessment of Residential Buildings with Ground Floor Commercial Function Specific to the Canyon Effect by Derin Hilal Bilmez, Cüneyt Diri

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Nonvanishing Eliashberg gap function in YBa2Cu3O7 above Tc by Guang-Lin Zhao

“…For T < Tc, there is a large anisotropy of superconducting gap on the Fermi surface of YBCO.[2,3] Furthermore, above Tc, such as 105 K, it was found that the real part of gap function is not zero at finite frequency, although for the frequency near 0, the real part of gap function is zero. …”
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Role of context on the perception of syllable composition by French and English listeners as a function of their dominant language by Elise Ryst

“…Thanks to a 3-step pilot auditory perception experiment, the study attempts to evaluate the perception of a syllable as a function of its context (as an isolated syllable or inside an entire word), and of the hearers (French or English native monolingual speakers, French-English bilinguals or English-French bilinguals).…”
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