Loss of CFHR5 function reduces the risk for age-related macular degeneration by Mary Pat Reeve, Stephanie Loomis, Eija Nissilä, Thomas W. Soare, Tobias Rausch, Zhili Zheng, Pietro DELLA BRIOTTA PAROLO, Daniel Ben-Isvy, Elias Aho, Emilia Cesetti, Yoko Okunuki, Helen McLaughlin, Johanna Mäkelä, FinnGen, Mitja Kurki, Michael E. Talkowski, Jan O. Korbel, Kip Connor, Seppo Meri, Mark J. Daly, Heiko Runz

“…We demonstrate through a FinnGen sample recall study that CFHR5 variant carriers exhibit dose-dependent reductions in serum levels of the CFHR5 gene product FHR-5 and two functionally related proteins at the locus. …”
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Fractal functions of exponential type that is generated by the $\mathbf{Q_2^*}$-representation of argument by M.V. Pratsovytyi, Ya. V. Goncharenko, I. M. Lysenko, S.P. Ratushniak

“…We consider function $f$ which is depended on the parameters $0<a\in R$, $q_{0n}\in (0;1)$, $n\in N$ and convergent positive series $v_1+v_2+...…”
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Peculiarities of functional neutrophil activity in rats having periodontitis in thesetting of toxic hepatitis by L. V. Vokhmintseva, N. N. Mayanskaya, S. S. Rymar′, P. A. Zheleznyi, A. P. Nadeyev, V. V. Vanyunina

“…On the 1-st and 7-th day, ratio of neutrophil-macrophag was determined in smears of the upper maxillas gingival, oxygen-dependent functional activity of neutrophils was assessed based upon HST-test, functional activity reserves were assessed by the stimulation index. …”
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CLASSIFICATION AND FUNCTIONS OF AUTHOR'S INDIVIDUAL NON-USUAL UNITS IN A PHILOSOPHICAL TEXT by S. Bredikhin, I. Makhova, O. Chudnova

“…The item focuses both on the functions and the pragmatics of non-usual units, which serve to explicate the ultimate concepts and ideas in texts belonging to the discourse of philosophy. …”
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Functional distribution of income in Africa: An estimation of the shares of owners of capital and labour in GDP by Idowu Shola Ajayi

“… The functional distribution of income in Africa is a critical aspect of economic analysis that focuses on how income is distributed among various factors of production. …”
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Assessing Predictive Ability of Dynamic Time Warping Functional Connectivity for ASD Classification by Christopher Liu, Juanjuan Fan, Barbara Bailey, Ralph-Axel Müller, Annika Linke

“…Functional connectivity MRI (fcMRI) is a technique used to study the functional connectedness of distinct regions of the brain by measuring the temporal correlation between their blood oxygen level-dependent (BOLD) signals. fcMRI is typically measured with the Pearson correlation (PC), which assumes that there is no lag between time series. …”
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Results of calculation and experimental studies of the functioning of the drive of an electric self-propelled machine by Oganyan E.A., Khmelev R.N.

“…The paper presents the results of computational and experimental studies of the functioning of the drive of a wheeled electric self-propelled vehicle. …”
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Functional Analysis of Thyroid Peroxidase Gene Mutations Detected in Patients with Thyroid Dyshormonogenesis by Srikanta Guria, Biswabandhu Bankura, Nisha Balmiki, Arup Kumar Pattanayak, Tapas Kumar Das, Anirban Sinha, Sudipta Chakrabarti, Subhankar Chowdhury, Madhusudan Das

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Positioning of the femoral tunnel in anterior cruciate ligament reconstruction: functional anatomical reconstruction by Pedro Baches Jorge, Diego Escudeiro, Nilson Roberto Severino, Cláudio Santili, Ricardo de Paula Leite Cury, Aires Duarte Junior, Luiz Gabriel Betoni Guglielmetti

“…The aim of this study was to review and update the literature in regard to the anatomy of the femoral origin of the ACL, the concept of the double band and its respective mechanical functions, and the concept of direct and indirect fibres in the ACL insertion. …”
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mRNA trafficking directs cell-size-scaling of mitochondria distribution and function by Joshua J. Bradbury, Georgia E. Hulmes, Ranjith Viswanathan, Guilherme Costa, Holly E. Lovegrove, Shane P. Herbert

“…Abstract The subcellular positioning of organelles is critical to their function and is dynamically adapted to changes in cell morphology. …”
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Bioactive Lipids in <i>Dunaliella salina</i>: Implications for Functional Foods and Health by Rita Pais, Tiago Conde, Bruna B. Neves, Marisa Pinho, Marta Coelho, Hugo Pereira, Alexandre M. C. Rodrigues, Pedro Domingues, Ana Maria Gomes, Ralph Urbatzka, Rosário Domingues, Tânia Melo

“…In conclusion, the lipid extract of <i>D. salina</i> has the potential to be used as a functional food ingredient or in the nutraceutical and cosmeceutical industries.…”
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Surface-Functionalizing Strategies for Multiplexed Molecular Biosensing: Developments Powered by Advancements in Nanotechnologies by Shangjie Zou, Guangdun Peng, Zhiqiang Ma

“…During this functionalizing process, nanomaterials can either be the objects of surface modification or the materials used to modify other base surfaces. …”
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An in vitro neurobacterial interface reveals direct modulation of neuronal function by gut bacteria by Juan Lombardo-Hernandez, Jesús Mansilla-Guardiola, Riccardo Aucello, Cristian Botta, Maria Teresa García-Esteban, Antonio Murciano-Cespedosa, David Muñoz-Rodríguez, Elisa Quarta, Álvaro Mateos González, Carmen Juan-Llamas, Kalliopi Rantsiou, Stefano Geuna, Luca Cocolin, Celia Herrera-Rincon

“…We developed an in vitro model using the foodborne bacterium Lactiplantibacillus plantarum and rat cortical neural cultures to study neuronal responses to bacterial presence through morphological, functional, and transcriptomic analyses. We found that L. plantarum adheres to neuronal surfaces without penetrating the soma. …”
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Structure and function of the lysine methyltransferase SETD2 in cancer: From histones to cytoskeleton by Christina Michail, Fernando Rodrigues Lima, Mireille Viguier, Frédérique Deshayes

“…Recently, SETD2 was further shown to methylate non-histone proteins particularly the cytoskeletal proteins tubulin and actin with subsequent impacts on cytoskeleton structure, mitosis and cell migration.Herein, we provide a review of the role of SETD2 in different cancers with special emphasis on the structural basis of the functions of this key lysine methyltransferase. Moreover, beyond the role of this enzyme in epigenetics and H3K36me3-dependent processes, we highlight the putative role of ''non-epigenetic/H3K36me3'' functions of SETD2 in cancer, particularly those involving the cytoskeleton.…”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

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Effects of fluvastatin, valsartan, and their combination on endothelial function in patients with arterial hypertension and dyslipidemia by T. Sh. Mirilashvili, S. V. Villewalde, Yu. V. Kotovskaya, Zh. D. Kobalava

“…To study the effects of an angiotensin II receptor antagonist (ARA II) valsartan, a statin (fluvastatin XL), and their combination on endothelial function (EF) in patients with arterial hypertension (AH) and dyslipidemia (DLP).Material and methods. …”
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The functional condition of fetoplacental system in pregnant women with thyroid gland autoimmune pathology by T. A. Melikova

“…To study the characteristics of the hormonal function of fetoplacental complex in pregnant women with autoimmune thyroid disease. …”
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Combination ‘v lyubom sluchaye’ (any way): Functioning in Text and Pragmatic Potential by N. Yu. Pilyugina

“…It is shown that at a certain position in the text on the border of the utterance, the combination performs the function of a text clip, forms standard text blocks. …”
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Intranasal insulin enhances resting-state functional connectivity in Type 2 Diabetes. by Zongpai Zhang, Vera Novak, Peter Novak, Christos Mantzoros, Long Ngo, Vasileios Lioutas, Weiying Dai

“…An MRI sub-study of the MemAID trial was conducted, involving a 24-week treatment with either intranasal insulin or placebo. Blood oxygen level-dependent (BOLD) functional MRI (fMRI) images were acquired on eighteen DM subjects at baseline and eleven DM subjects (eight DM-INI patients and three DM-Placebo) at the end-of-treatment. …”
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Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo. by Olivier Morteau, Samkeliso Blundell, Aron Chakera, Sophia Bennett, Charita M Christou, Philip D Mason, Richard J Cornall, Christopher A O'Callaghan

“…<h4>Results</h4>Overnight ex vivo treatment of peripheral blood cells from healthy controls with ciclosporin or tacrolimus inhibited NK cell degranulation and IFN-γ production in a dose-dependent manner. A similar impairment of function was seen in NK cells from patients treated in vivo with calcineurin inhibitors. …”
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