From preneoplastic lesion to heterogenous tumor: recent insights into hepatoblastoma biology and therapeutic opportunities by Jun Yang, Andrew M. Davidoff, Andrew J. Murphy

“…Early genomic studies revealed that hepatoblastoma has the lowest mutational burden of any human cancer, however, recent advances in single-cell RNA-seq, multiomics, spatial transcriptomics, and functional genomics screenings have revealed substantial complexity. …”
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DYNAMIC LOAD OF THE THIN CONICAL RADOME WITH A CONSIDERATION OF ATTACHED ADDITIONAL MASS by I. K. Turkin, D. A. Rogov

“…The temperature field can be specified as any functional dependence in both circumferential and longitudinal coordinates of a thin-walled axisymmetric shell. …”
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Experimental Verification of the Weibull Distribution in a Reverberation Chamber by Jianhua Xu, Yongjiu Zhao, Qian Xu

“…A Weibull distribution has been proposed for the probability density function (PDF) of the magnitude of the E-field in a reverberation chamber (RC). …”
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Da Vinci’s friction for granular media by Assaf Miron, Rafael Tadmor, Victor Multanen, Shmulik Pinkert

“…We show, for the first time, that kinetic friction coefficients of such systems can be described as a function of the lubricating fluid and the shape of the granules, without any fitting parameters. …”
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Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome by Xingyun Quan, Yukun Yang, Xiaolong Liu, Britta Kaltwasser, Matthias Pillath-Eilers, Bernd Walkenfort, Sylvia Voortmann, Ayan Mohamud Yusuf, Nina Hagemann, Chen Wang, Mike Hasenberg, Dirk M. Hermann, Ulf Brockmeier

“…To define the role of the autophagy hub protein p62/SQSTM1 in I/R injury, we conducted gain-of-function and loss-of-function experiments in a set of cell types, including two neuron-like cell lines, primary neurons, brain endothelial and astroglial-like cells, which we combined with mouse ischemic stroke studies. p62 levels post-I/R increased alongside intracellular ROS changes. p62 overexpression increased and p62 knockdown or pharmacological deactivation reduced I/R injury. …”
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Performance Analysis of Dual-Hop RF-UWOC Systems by Hongjiang Lei, Yiyao Zhang, Ki-Hong Park, Imran Shafique Ansari, Gaofeng Pan, Mohamed-Slim Alouini

“…Furthermore, by utilizing the expansion of Meijer&#x0027;s <inline-formula><tex-math notation="LaTeX">$G$</tex-math></inline-formula>-function and Fox&#x0027;s <inline-formula><tex-math notation="LaTeX">$H$</tex-math></inline-formula>-function, the closed-form expressions for the asymptotic OP and ABER are derived when the average signal-to-noise ratio of both links tends to infinity. …”
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Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects by Louise Kaldjob-Heinrich, Sandro Nuciforo, Steffen Lemke, Aaron Stahl, Stefan Czemmel, Sepideh Babaei, Lauriane Blukacz, Marie-Anne Meier, Yizheng Zhang, Christian M. Schürch, Irene Gonzalez-Menendez, Pascal Woelffing, Nisar P. Malek, Veit Scheble, Sven Nahnsen, Manfred Claassen, Markus Templin, Hans Bösmüller, Markus H. Heim, Daniel Dauch, Michael Bitzer

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Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults by Michael G. Nanna, Daniel Wojdyla, Eric D. Peterson, Ann Marie Navar, Jeff D. Williamson, Lisandro D. Colantonio, Stephen Y. Wang, Yasser Jamil, Alain G. Bertoni, Musarrat Nahid, Abdulla A. Damluji, Parag Goyal, Sarwat I. Chaudhry, Thomas M. Gill, Karen P. Alexander

“…Variable selection, including functional status, was based on the least absolute shrinkage and selection operator method. …”
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Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom by Yun MA, Siyuan HE

“…In contrast, the US predominantly employs a “gap closing” strategy, seeking to resolve the issues of land ownership and functional discrepancy through legal tools and land regulation. …”
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Simultaneous distributed generation and electric vehicles hosting capacity enhancement through a synergetic hierarchical bi-level optimization approach based on demand response and... by Zenhom M. Zenhom, Shady H. E. Abdel Aleem, Essam Aboul Zahab, Tarek A. Boghdady

“…To further support the proposed objective function, DR is mixed with the optimal Volt/VAR controlling offered by SIs. …”
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Low-temperature oxidation of hexagonal boron nitride during oxidative dehydrogenation reactions by Mehran Sajad, Kateřina Knotková, Roman Bulánek, Ota Bludský, Miroslav Rubeš

“…This study explores the role of gas-phase radicals, such as n-propyl and hydroxyl radicals, in initiating the oxidation process, leading to the formation of oxygen-functionalized h-BN edges. Using ab initio molecular dynamics (AIMD) and density functional theory (DFT) calculations, we reveal the mechanism of h-BN oxidation, including hydrogen abstraction, molecular oxygen adsorption, and nitrogen oxide desorption. …”
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Modern possibilities of effective cough therapy in acute respiratory infections in children by N. A. Geppe, E. G. Kondyurina, T. E. Pak

“…In choosing the therapeutic strategy, the doctor must «manage» cough, using the preparations depending on the clinical situation, those which influence on cough reflex or those which normalize drainage function of the respiratory tract. …”
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A Road Pricing Model for Congested Highways Based on Link Densities by Louis de Grange, Rodrigo Troncoso, Felipe González

“…The methodology solves a nonlinear constrained optimization problem whose objective function maximizes toll revenue or highway use (2 scenarios). …”
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Asymptotic Behaviors of Nearest Neighbor Kernel Density Estimator in Left-truncated Data by V. Fakoor

“…Moreover, the proposed estimator is used to estimate  the density function of a real data set.…”
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Longitudinal Survival Analysis Using First Hitting Time Threshold Regression: With Applications to Wiener Processes by Ya-Shan Cheng, Yiming Chen, Mei-Ling Ting Lee

“…We demonstrate the usage of LTR in two case scenarios, namely, analyzing laser reliability data without covariates, and cardiovascular health data with time-dependent covariates. Moreover, we provide a simple-to-use R function for LTR estimation for applications using Wiener processes.…”
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Fecal Microbiota Transplantation: Past, Present and Future by N. V. Yevdokimova, T. V. Chyornenkaya

“…Although the exact mechanism of action is not entirely clear, it is believed to restore the composition and function of the intestinal microbiota in diseased patients. …”
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Considerations on the Development of Therapeutics in Vascular Calcification by Ana M. Valentin Cabrera, Sophie K. Ashbrook, Joshua D. Hutcheson

“…In both cases, vascular smooth muscle cells undergo osteogenic differentiation, leading to mineral deposition and associated wall stiffening; however, the effects on cardiovascular function and morbidity vary depending on mineral morphology and location. …”
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Multi-objective Optimal Design for Passive Part of Hybrid Active Power Filter Based on Bacterial Foraging and Particle Swarm Optimization by 李圣清, 李永安, 罗晓东, 曾黎琳, 何政平

“…It takes the capacity of reactive power compensation, the harmonic effect after compensation and the original investment cost as three objectives, and restricts the important goal and dynamic constants as a method to achieve comprehensive fitness function, and then solves the multi-objective optimization problem. …”
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Normal Criterion Concerning Shared Values by Wei Chen, Yingying Zhang, Jiwen Zeng, Honggen Tian

“…We study normal criterion of meromorphic functions shared values, we obtain the following. Let F be a family of meromorphic functions in a domain D, such that function f∈F has zeros of multiplicity at least 2, there exists nonzero complex numbers bf,cf depending on f satisfying (i)  bf/cf is a constant;  (ii)min {σ(0,bf),σ(0,cf),σ(bf,cf)≥m} for some m>0;  (iii)  (1/cfk-1)(f′)k(z)+f(z)≠bfk/cfk-1 or (1/cfk-1)(f′)k(z)+f(z)=bfk/cfk-1⇒f(z)=bf, then F is normal. …”
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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities by Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O'Brien, Brenda Andrews, Charles Boone, Jason Moffat

“…Abstract Improved efforts are necessary to define the functional product of cancer mutations currently being revealed through large‐scale sequencing efforts. …”
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