Chlamydial entry involves TARP binding of guanine nucleotide exchange factors. by B Josh Lane, Charla Mutchler, Souhaila Al Khodor, Scott S Grieshaber, Rey A Carabeo

“…We show that TARP participates directly in chlamydial invasion activating the Rac-dependent signaling cascade to recruit actin. TARP functions by binding two distinct Rac guanine nucleotide exchange factors (GEFs), Sos1 and Vav2, in a phosphotyrosine-dependent manner. …”
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Measuring. Monitoring. Management. Control by A.J. Alieva, Kh.S. Alieva, M.G. Ashrafov, N.Kh. Mustafazade

“…In the optimal mode, this functionality should reach its maximum if some restrictive condition is imposed on the specified dependence. …”

A new algorithm for automating power supply of an AC traction network with a sectioning points on switches by L. A. German, A. Yu. Popov, A. V. Samorukov, D. V. Ishkin, D. V. Yakunin, K. S. Subkhanverdiev

“…The article considers modern sectioning points on contact network and determining the location of the damage, imthe switches, which differs by the introduction of new functions for plemented in the IntTer smart terminal. …”
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Error Estimate of Eigenvalues of Perturbed Higher-Order Discrete Vector Boundary Value Problems by Haiyan Lv, Yuming Shi, Guojing Ren

“…A suitable admissible function space is first introduced, a new variational formula of eigenvalues is then established under certain nonsingularity conditions, and error estimates of eigenvalues of problems with small perturbation are finally given by using the variational formula. …”
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THE INTENSITY OF EMOTIONAL TENSION IN CHILDREN WITH CLEFT PALATE IN RESPONSE TO SITUATIONAL STRESS by P. I. Tkachenko, N.M. Lokhmatova, S.A. Byеlokon, V.A. Dobroskok

“… Numerous experimental studies and clinical observations indicates that in one and the same stress situations a human being and animals express a different resistance to emotional stress, the severity of which depends greatly on the individual characteristics of self-regulation of different body functional systems. …”
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Updates on Inflammatory Molecular Pathways Mediated by ADAM17 in Autoimmunity by Margherita Sisto, Sabrina Lisi

“…ADAM17 is a member of the disintegrin and metalloproteinase (ADAM) family of transmembrane proteases with immunoregulatory activity in multiple signaling pathways. The functional ADAM17 is involved in the shedding of the ectodomain characterizing many substrates belonging to growth factors, cytokines, receptors, and adhesion molecules. …”
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Optimal control for infinite-dimensional linear systems with Markovian jumps in Borel spaces by Viorica Mariela Ungureanu, Iulia Iarina Ungureanu

“…The main objective is to minimize an infinite-horizon, non-negative quadratic cost functional for time-dependent LSMJs by generalizing previous findings on finite - dimensional systems to the infinite-dimensional case. …”
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The electronic band structure of hexagonal silicon polytypes by Chizhova Anastasia, Nikolskaya Alena, Zaitseva Ekaterina, Konakov Anton

“…The BS for the 9R polytype calculated by EPM was almost identical to that obtained by the density functional theory method. This result indicates the possibility of using EPM for constructing BSs of various polytypes. …”
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An Overview: A Design Strategy for Dioxide Carbon QCM Gas Sensor Based on MOFs or COFs by Xukun Wang, Tong Zhang

“…Metal–organic frameworks (MOFs)/covalent–organic frameworks (COFs), as a functional material, have unique physical and chemical properties and are capable of trapping and adsorbing gases in large quantities. …”
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Preparation and Photocatalytic Activity of TiO𝟐-Deposited Fabrics by Yang Xu, Wenzheng Xu, Fenglin Huang, Qufu Wei

“…The photocatalytic activity of the functional nonwoven fabrics was evaluated by the degradation of methylene blue. …”
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Experimental thermal analysis of brake cooling relative to mass flow of air through a ventilated brake disc by Tarun Kadri Sathiyan, Alexey Vdovin, Staffan Johansson, Simone Sebben

“…The brake system is crucial for vehicle safety and, thus, needs to be validated from a functional perspective.A test rig setup to accommodate a brake caliper fixture, as well as a funnel housing an anemometer, was purposefully designed and manufactured. …”
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25 by Paul Richard J Yulo, Nicolas Desprat, Monica L Gerth, Barbara Ritzl-Rinkenberger, Andrew D Farr, Yunhao Liu, Xue-Xian Zhang, Michael Miller, Felipe Cava, Paul B Rainey, Heather L Hendrickson

“…We conclude by presenting two testable hypotheses, one of which posits that heterogeneity stems from non-functional cell wall synthesis machinery, while the second posits that the machinery is functional, albeit stalled. …”
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Using 3D observations with high spatio-temporal resolution to calibrate and evaluate a process-focused cellular automaton model of soil erosion by water by A. Eltner, D. Favis-Mortlock, O. Grothum, M. Neumann, T. Laburda, P. Kavka

“…They also highlight different strengths and weaknesses of the model. Depending on the focus of the evaluation, an ensemble of objective functions may not always be necessary.…”
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Image complexation in the following coordinator of homing head to improve shooting efficiency of anti-aircraft missile system type «Strela-10M2» by D. S. Sharak, A. Yu. Liplianin, A. V. Khizhniak

“…A variant to reduce the firing cycle of AAMS by eliminating the fact of switching operating modes is presented. It's shown the dependence of likelihood of fire mission execution by a subunit armed with AAMS as a function of the image quality of the accompanied target characterized by a standard deviation of pixel brightness in the tracking monitor of the HH.…”
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C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice by Toru Tanaka, Naoto Sasaki, Aga Krisnanda, Hilman Zulkifli Amin, Ken Ito, Sayo Horibe, Kazuhiko Matsuo, Ken-ichi Hirata, Takashi Nakayama, Yoshiyuki Rikitake

“…Mechanistically, CCR4 deficiency in Tregs impaired their suppressive function and tended to inhibit their migration to the atherosclerotic aorta, and subsequently augmented Th1 cell-mediated immune responses through defective regulation of dendritic cell function, which accelerated aortic inflammation and atherosclerotic lesion development. …”
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The Role of Regulatory T Cell in Nontypeable Haemophilus influenzae-Induced Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Xuewa Guan, Yanjiao Lu, Guoqiang Wang, Peter Gibson, Fang Chen, Keyong Fang, Ziyan Wang, Zhiqiang Pang, Yingqiao Guo, Junying Lu, Yuze Yuan, Nan Ran, Fang Wang

“…Weight loss and lung function decline were observed in smoke-exposed mice. …”
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SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire by Somen K Mistri, Brianna M Hilton, Katherine J Horrigan, Emma S Andretta, Remi Savard, Oliver Dienz, Kenneth J Hampel, Diana L Gerrard, Joshua T Rose, Nikoletta Sidiropoulos, Dev Majumdar, Jonathan E Boyson

“…During thymic development, most γδ T cells acquire innate-like characteristics that are critical for their function in tumor surveillance, infectious disease, and tissue repair. …”
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Sarcopenia in a Multiethnic State: A Cross-Sectional Data Analysis of Multicentre Indonesia Longitudinal Aging Study by Kuntjoro Harimurti, Siti Setiati, Czeresna Heriawan Soejono, IGP Suka Aryana, Sri Sunarti, Fatichati Budiningsih, Roza Mulyana, Lazuardhi Dwipa, Agus Sudarso, Rensa Rensa, Rahmi Istanti, Muhammad Khifzhon Azwar, Jessica Marsigit

“…Conclusion: One in five Indonesian community-dwelling older adults had sarcopenia, associated with female sex, dependent functional capacity, frailty, and history of fall. …”
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Deubiquitinating Enzymes and Bone Remodeling by Yu-chen Guo, Shi-wen Zhang, Quan Yuan

“…Deubiquitinases, which are grouped into five families, remove ubiquitin from target proteins and are involved in several cell functions. Importantly, a number of deubiquitinases mediate bone remodeling through regulating differentiation and/or function of osteoblast and osteoclasts. …”
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MAIT and iNKT cells in tissue homeostasis and repair by Rafael Almeida Paiva, Marion Salou

“…Furthermore, we underline TCR- and/or cytokine-dependent mechanisms and potential redundant, non-redundant or even opposing functions.…”
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