Regulatory mechanism of ghrelin on testosterone secretion in type 1 diabetic rats by Chien-Chen Lu, Chia-Hsin Chang, Jou-Chun Chou, Po-Ling Yu, Paulus S Wang

“…Consequently, ghrelin may play a regulatory role in gonadal function. Male Sprague–Dawley rats were randomly assigned to four groups: the control, ghrelin-treated, diabetic, and diabetic plus ghrelin treatment groups. …”
Get full text

Platelet recruitment kinetics are impacted by von Willebrand factor quality in hemostatic adjuncts by Kimberly A. Thomas, Alice Liu, David L. Bark, Jr., Philip C. Spinella, Susan M. Shea

“…There was no difference in intrinsic VWF function between adjuncts in static, nonflowing assays, yet in a flow-dependent vortexing assay, PR reduced VWF cleavage by ADAMTS13, despite equivalent ADAMTS13 activity, suggesting impaired biophysical elongation and extension of VWF in PR-CryoFC, resulting in reduced cleavage and platelet binding capacity. …”
Get full text

HEIX1 Mutation Effects on Endoplasmic Reticulum Stress, Caspase Activation, and JNK2 Pathways by MA Dragh, ZS Al-Allak, ZZG Allami

“…This study examines the molecular mechanisms underlying HEIX1 loss-of-function mutations in S2 cells, focusing on P-ERK and JNK pathway activation and their effects on cellular stress responses. …”
Get full text

Deletion of Mettl3 at the Pro-B Stage Marginally Affects B Cell Development and Profibrogenic Activity of B Cells in Liver Fibrosis by Xinmei Kang, Shuhan Chen, Lijie Pan, Xiaoqi Liang, Di Lu, Huaxin Chen, Yanli Li, Chang Liu, Mian Ge, Qi Zhang, Qiuli Liu, Yan Xu

“…In summary, our study demonstrated that deletion of Mettl3 from the pro-B stage on has minimal effects on B cell development and function, as well as profibrogenic activity of B cells in liver fibrosis, revealing a stage-specific dependence on Mettl3-mediated m6A of B cell development.…”
Get full text

Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. by Matthew Van De Pette, Simon J Tunster, Grainne I McNamara, Tatyana Shelkovnikova, Steven Millership, Lindsay Benson, Stuart Peirson, Mark Christian, Antonio Vidal-Puig, Rosalind M John

“…Conversely, loss-of-function of Cdkn1c resulted in the complete developmental failure of the brown adipocyte lineage with a loss of markers of both brown adipose fate and function. …”
Get full text

Phy-ChemNODE: an end-to-end physics-constrained autoencoder-NeuralODE framework for learning stiff chemical kinetics of hydrocarbon fuels by Tadbhagya Kumar, Anuj Kumar, Anuj Kumar, Pinaki Pal

“…Effects of various model hyperparameters, such as relative weighting of different terms in the loss function and dimensionality of the AE latent space, on the accuracy of Phy-ChemNODE are assessed. …”
Get full text

Identification of widely conserved biosynthetic gene cluster involved in pigment production of Bacillus subtilis by Rune Overlund Stannius, Christopher A. Dunlap, Estelle Morvan, Mélanie Berbon, Sophie Lecomte, Antoine Loquet, Ákos T. Kovács

“…This study describes the chemical and biological features of a new class of SM BGC, which we hope will serve to improve the current BGC discovery pipelines in Bacilli.IMPORTANCEIdentification of novel microbial secondary metabolites (SMs) and their biosynthetic gene cluster (BGC) has become increasingly difficult, especially in Bacilli, as the tools for screening and genome mining are dependent on clear function or similarity to already known BGCs. …”
Get full text

On Best Proximity Point Theorems and Fixed Point Theorems for -Cyclic Hybrid Self-Mappings in Banach Spaces by M. De la Sen

“…This paper relies on the study of fixed points and best proximity points of a class of so-called generalized point-dependent -hybrid -cyclic self-mappings relative to a Bregman distance , associated with a Gâteaux differentiable proper strictly convex function in a smooth Banach space, where the real functions and quantify the point-to-point hybrid and nonexpansive (or contractive) characteristics of the Bregman distance for points associated with the iterations through the cyclic self-mapping. …”
Get full text

Formation and Regulation of Mitochondrial Membranes by Laila Cigana Schenkel, Marica Bakovic

“…Understanding the role of phospholipids in the mitochondrial membrane and their metabolism will shed light on the molecular mechanisms involved in the regulation of mitochondrial function and in the mitochondrial-related diseases.…”
Get full text

Nonpoint Symmetry and Reduction of Nonlinear Evolution and Wave Type Equations by Ivan Tsyfra, Tomasz Czyżycki

“…By using operators of Lie-Bäcklund symmetries we construct the solutions of nonlinear hyperbolic equations depending on arbitrary smooth function of one variable too.…”
Get full text

Hysteresis properties of two-dimensional spin systems by A.Yu. Polyakov, T.V. Lyutyy, A.V. Rot-Serov

“…At the same time, the exchange bias field shows the non-uniform dependence, because it is a function of outer layer type. …”
Get full text

Exponential Stabilizability of Switched Systems with Polytopic Uncertainties by Xia Zhang, Zun-Quan Xia, Yan Gao

“…The exponential stabilizability of switched nonlinear systems with polytopic uncertainties is explored by employing the methods of nonsmooth analysis and the minimum quadratic Lyapunov function. The switchings among subsystems are dependent on the directional derivative along the vertex directions of subsystems. …”
Get full text

Lipofibromatous Hamartoma of the Superficial Peroneal Nerve with Significant Macrodactyly and Macrodystrophia Lipomatosa by Rohini Prasad, Arun Kumar Rajeswaran, Karishmah Senthil Kumar, Purvashree Prasad

“…We discuss the clinical presentation, distinguishing features, and the surgical technique chosen for maximum functional outcome, along with a review of the literature. …”
Get full text

Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research by Candice Taguibao, Salma Ajraoui, Jake Centra, Kieran F. Reid, Christina Daskalopoulou, Alberto Conde Freniche, Alan L. Hamilton, Astrid M. H. Horstman, Benjamin X. Collins, Jessilyn Dunn, Elena S. Izmailova

“…Thematic synthesis revealed five meaningful aspects of health (MAH) related to PA: ambulation‐dependent activities, balance‐dependent activities, activities needing upper limb function, changing body positions, and participating in activities of different intensities. …”
Get full text

The Influence of Occupational Activity on Leisure Time of the Disabled People Who Live in the Rural Areas of the Lubelskie Voivodship by Dominik Dąbrowski, Marek Kuźmicki

“…These two dimensions in a very essential way influence each other depending on socio-demographic characteristics. In the case of disabled people vocational activity fulfils not only an economic function but also holds essential functions of rehabilitation and integration. …”
Get full text

Robust Stability Criteria for Uncertain Neutral Systems with Interval Nondifferentiable Time-Varying Delay and Nonlinear Perturbations by W. Weera, P. Niamsup

“…The constraint on the derivative of the time-varying delay is not required, which allows the time-delay to be a fast time-varying function. Based on the Lyapunov-Krasovskii theory, we derive new delay-dependent stability conditions in terms of linear matrix inequalities (LMIs) which can be solved by various available algorithms. …”
Get full text

Resilient Robust Finite-Time L2-L∞ Controller Design for Uncertain Neutral System with Mixed Time-Varying Delays by Xia Chen, Shuping He

“…The delay-dependent resilient robust finite-time L2-L∞ control problem of uncertain neutral time-delayed system is studied. …”
Get full text

The impact of fear and refuge on the dynamics of predator-prey model: Stability and simulation by Aseel Hameed, Hassan F. Al-Husseiny

“…The appropriate Lyapunov function is used to show the general stability of the balance points. …”
Get full text

THE ROLE OF NO SYNTHESIS CORRECTION IN PREVENTION OF CARDIOVASCULAR HYPERTENSIVE REMODELING by V. I. Buvaltsev, S. Y. Mashina, D. A. Pokidyshev, B. V. Smirin, L. A. Bayda, V. Y. Malyshev, E. B. Manukina

“…Comparative study of preventive effects of two beta-blocking drugs with different mode of action was performed on SHRSP and WKY rats. Morphological and functional parameters – blood pressure, endothelium-dependent vascular relaxation, plasma level of nitric oxide stable metabolites (nitrite/nitrate), cardiac hyperthrophy and vascular remodeling were monitored during chronic nebivolol and metoprolol injection in parallel groups of rats. …”
Get full text

Changes in the Surface Chemistry and Adsorptive Properties of Active Carbon Previously Oxidized and Heat-Treated at Various Temperatures. III. Studies of the Adsorption of Organic... by A. Derylo-Marczewska, A. Swiatkowski, H. Grajek, S. Biniak, Z. Witkiewicz

“…The characteristics of the surface functional groups and the porous structure of the samples obtained were estimated using various experimental methods. …”
Get full text