P03 | THE ROLE OF FILAMIN A IN REGULATING BREAST CANCER CELL BEHAVIOR AND TUMOR MICROENVIRONMENT INTERACTIONS

“…However, due to the cell line-specific effects and conflicting reports in the literature, further research is required to clarify the context-dependent functions of FLNa within diverse tumor microenvironments. …”
Get full text

INVESTIGATION OF BIOKINETIC PECULIARITIES OF STRONTIUM-90 METABOLISM MODEL AND POSSIBILITY OF AN ESTIMATION OF RADIONUCLIDE INTAKE LEVEL BASING ON THE RESULTS OF THE MEASUREMENTS O... by V. S. Repin

“…Besides, temporary depots of radionuclide fixation fulfill the function of averaging of radionuclide intake in a case of daily intake levels, randomly timely distributed.…”
Get full text

STUDY OF THE CELLULAR COMPONENT OF IMMUNE SYSTEM IN CASES OF TRAUMATIC MANDIBULAR FRACTURE IN PATIENTS OF DIFFERENT PSYCHOSOMATIC PERSONALITY TYPES by Ya.P. Nahirniy, V. L. Fesyk

“…The aim of the research was to study functional disorders of immune system cellular component in patients with traumatic mandibular fractures depending on psychosomatic type of personality. …”
Get full text

Ethnic characteristics of bone remodeling in female patients with type 2 diabetes mellitus by T. P. Bardymova, M. V. Shestakova, Ya. P. Sandakov, M. V. Mistiakov, M. V. Berezina

“…Background: Structural and metabolic disorders of bone tissue in women with T2DM have no clinical manifestations, but they are accompanied by the risk of fractures.Aim: To study the parameters of bone metabolism, BMD and microarchitectonics in female patients with T2DM in the Buryat population.Materials and methods: The observational single-center one-stage controlled study included 73 women with T2DM, which were divided into 2 groups depending on the functional state of the ovaries (reproductive and postmenopausal periods). …”
Get full text

Rationally targeted anti-VISTA antibody that blockades the C-C’ loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor g... by Dipti Thakkar, Lillian Liu, Bhushan Dharmadhikari, Shalini Paliwal, Siyu Guan, Shreya Kar, Nikhil K Tulsian, Joshua J Gruber, Leah DiMascio, Konrad H Paszkiewicz, Piers J Ingram, Jerome D Boyd-Kirkup

“…The expression of VISTA on normal immune cell subtypes argues for a neutralizing non-depleting antibody, however, previous reported anti-VISTA antibodies use IgG1 Fc isotypes that deplete VISTA+ cells by antibody dependent cellular cytotoxicity/complement dependent cytotoxicity and these antibodies have shown fast serum clearance and immune toxicities.Method Here we used a rational antibody discovery approach to develop the first Fc-independent anti-VISTA antibody, HMBD-002, that binds a computationally predicted functional epitope within the C-C-loop, distinct from other known anti-VISTA antibodies. …”
Get full text

Investigations on auditory spaciousness of large acoustic sources within a room by K. RUDNO-RUDZIŃSKI, J. RENOWSKI

“…Size evaluations dit not reflect the source's length, but were in linear dependence with the maximal value of a normalized cross correlation function of signals reaching the listener's left and right ear. …”
Get full text

Sorption of Radiocaesium onto Powdered and Compacted Rectorite Studied by Batch and Capillary Methods by Lei Chen, Xianjin Yu

“…The sorption of radiocaesium onto Na-rectorite as a function of pH value under ambient conditions was studied by batch and capillary methods. …”
Get full text

Thresholds of biological action of ultrasound by Valentin AKOPYAN

“…The character of the regulative mechanisms in a cell depends on the degree to which the intracellular medium has changed and, hence, on the degree of change in the cell membrane permeability which is dependent on the intensity of ultrasound action. …”
Get full text

O Naprzemienności Ruchu przy Pewnym Tłumieniu Nieliniowym by Z. Osiński

“…Making use of Refs. [1], [2] supplementing them with his own considerations, he finds that the oscillatory nature of the motion depends only on the coefficient of the first power of the power expansion of the function R(%). …”
Get full text

How early olfactory experiences influence brain development in mice by Hirofumi Nishizumi

“…Mammalian sensory systems develop through both activity-dependent and activity-independent processes. While the foundational neural circuits are encoded by genetics, their refinement depends on activity-driven mechanisms. …”
Get full text

The Sorption of Th(IV) Ions onto Montmorillonite: The Effect of pH, Ionic Strength and Fulvic Acid by Lei Chen, Xianjin Yu, Zengdian Zhao, Yunhui Dong

“…The sorption of Th(IV) ions onto montmorillonite and its cross-linked counterpart in the presence/absence of fulvic acid was investigated via a batch technique as a function of pH and fulvic acid concentration. The results obtained indicate that the sorption of Th(IV) ions was strongly dependent on the pH value of its solution, with the presence of fulvic acid enhancing such sorption at low pH values. …”
Get full text

Intraoperative transit time flow measurement in patients with diffuse coronary artery disease in the prevention of aortocoronary bypass graft occlusion by R. S. Akchurin, A. A. Shiryaev, V. P. Vasiliev, D. M. Galyautdinov, V. Yu. Zaikovsky, Sh. D. Mukimov

“…TTFM analysis showed the worst hemodynamic parameters and a higher rate of suboptimal function in group 1; blood flow parameters were comparable in groups 2 and 3. …”
Get full text

Exploring the Dynamic Changes of Brain Lipids, Lipid Rafts, and Lipid Droplets in Aging and Alzheimer’s Disease by Michele Cerasuolo, Irene Di Meo, Maria Chiara Auriemma, Giuseppe Paolisso, Michele Papa, Maria Rosaria Rizzo

“…These changes can affect the function of brain cells and may contribute to neurodegenerative diseases such as Alzheimer’s disease. …”
Get full text

Aging amplifies sex differences in low alpha and low beta EEG oscillations by Chuanliang Han, Vincent C.K. Cheung, Rosa H.M. Chan

“…Biological sex profoundly shapes brain function, yet its precise influence on neural oscillations was poorly understood. …”
Get full text

Angiogenic and Immunomodulatory effects of embryonic stem cell derived mesenchymal stem cells in a murine model of ischemic hindlimb by Do Jung Kim, Young-Nam Youn, Ji Min Kim, Sang-Hyun Lim

“…G1 exhibited normal blood perfusion and motor function, whereas E-MSC-treated groups (G3–G5) demonstrated improved perfusion compared to G2. …”
Get full text

Two cases of unresectable hepatocellular carcinoma treated via atezolizumab and bevacizumab combination therapy by Ryosuke Tsunemitsu, Motoyasu Tabuchi, Shinya Sakamoto, Kenta Ogi, Manabu Matsumoto, Jun Iwata, Takehiro Okabayashi

“…R0 resection with left trihepatectomy was impossible because of insufficient liver function, and combination therapy using atezolizumab and bevacizumab was initiated. …”
Get full text

Respiratory Muscle Strength in Patients with Coronary Heart Disease and Different Musculoskeletal Disorders by E. D. Bazdyrev, N. A. Terentyeva, N. A. Galimova, K. E. Krivoshapova, O. L. Barbarash

“…Correlation analysis revealed an association between RMS and muscle function.…”
Get full text

Synchrony of Nitrogen Wet Deposition Inputs and Watershed Nitrogen Outputs Using Information Theory by Desneiges S. Murray, Edom Moges, Laurel Larsen, Michelle D. Shattuck, William H. McDowell, Adam S. Wymore

“…Wet deposition N contributed information to river N at timescales greater than quick‐flow runoff generation, indicating that river N losses are a lagged non‐linear function of hydro‐biogeochemical forcings. River DON received the most information from all three wet deposition N solutes while wet deposition DON and NH4+ contributed the most information to all three river N solutes. …”
Get full text

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication. by Wan-Shan Yang, Mel Campbell, Pei-Ching Chang

“…Our results revealed that SUMO conjugation mediates an epigenetic regulatory function of JMJD2A and suggests that inhibiting JMJD2A SUMOylation may be a novel avenue for anti-cancer therapy.…”
Get full text

Prevalence of fatigue among pediatric cancer patients in Egypt by Nourhan Abdalkader, Alaa Mahmoud Zawrah, Shaimaa Lasheen, Ahmed Mohamed Yehia Osman

“…Moreover, significant predicting factors included depression, mobility especially upper extremity function, and treatment status. Fatigue screening and controlling these factors in pediatric oncology patients is advisable to improve their medical care plan.…”
Get full text