Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus. by Chantal E Hargreaves, Chisako Iriyama, Matthew J J Rose-Zerilli, Sietse Q Nagelkerke, Khiyam Hussain, Rosalind Ganderton, Charlotte Lee, Lee R Machado, Edward J Hollox, Helen Parker, Kate V Latham, Taco W Kuijpers, Kathleen N Potter, Sarah E Coupland, Andrew Davies, Michael Stackpole, Melanie Oates, Andrew R Pettitt, Martin J Glennie, Mark S Cragg, Jonathan C Strefford

“…Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). …”
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Unraveling the nexus: Sleep's role in ferroptosis and health by Peng-cheng Zhao, Zhen-yu Wu, Yu-hang Zhu, Tao-wu Gong, Zhao-qiong Zhu

“…Sleep is an important physiological process to maintain physiological health, which involves the regulation of many systems in the body, which is not only closely related to hormone balance, immune system and nervous system function in the body. Recent studies have emphasized the complex relationship between sleep and cell death mechanisms. …”
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Are physical factors associated with poor prognosis following a whiplash trauma?: a protocol for a systematic review and data synthesis by Deborah Falla, Alessio Gallina, Ahmed Alalawi

“…Studies will be required to assess the prognostic ability of one or more physical factors that directly involve a body function and/or structure and can be measured objectively. …”
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Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-1/Smad3 signaling and miR-181a expression by Jingsong Shen, Min Huang, Zixu Ye, Yuling Jing, Ziyang Yuan, Zeming Xiang, Miao Ding, Tao Li, Qiang Ye

“…After 4 weeks, ventricular fibrillation thresholds were assessed via electrical stimulation. Cardiac function (echocardiography), fibrosis (Masson’s trichrome staining), and molecular markers (transforming growth factor-β1, Smad3, miR-181a; assessed via western blotting/quantitative polymerase chain reaction) were analyzed. …”
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Effect of Biosynthesized Zinc oxide Nanoparticles on Phenotypic and Genotypic Biofilm Formation of Proteus mirabilis by Noor Hamza Faiq, Mais E. Ahmed

“…From all findings conducted by this study, zinc oxide nanoparticles can function as anti-bacterial agent in concentration dependent manner. …”
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Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. by Kyoko Nakamura, Toshiaki Kogame, Hiroyuki Oshiumi, Akira Shinohara, Yoshiki Sumitomo, Keli Agama, Yves Pommier, Kimiko M Tsutsui, Ken Tsutsui, Edgar Hartsuiker, Tomoo Ogi, Shunichi Takeda, Yoshihito Taniguchi

“…Previous studies show that CtIP plays a critical role in the generation of 3' single-strand overhang at "clean" DSBs, thus initiating homologous recombination (HR)-dependent DSB repair. To analyze the function of CtIP in detail, we conditionally disrupted the CtIP gene in the chicken DT40 cell line. …”
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Optimal selection of diagnostic method for diabetes mellitus using complex bipolar fuzzy dynamic data by Hanan Alolaiyan, Maryam Liaqat, Abdul Razaq, Umer Shuaib, Abdul Wakil Baidar, Qin Xin

“…We formulate a modified score function to address the shortcomings of the current score function in the CBF settings. …”
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Endothelial Dysfunction in the Young Adult: a Retrospective Cohort Study on the Effect of Low Birth Weight by Augustine Purnomowati, Sri Hartini KS Kariadi, Tri H Achmad, Johanes C Mose, Budhi Setianto

“… Aim: to investigate the effect of low birth weight (LBW) on endothelial function, and to determine the role of plasma adiponectin in endothelial dysfunction by conducting flow mediated brachial artery (FMBA) test or vasodilation response (VR) and by measuring plasma asymmetrical dimethylarginine (ADMA) of young adults born with LBW. …”
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Frequency model of an essentially nonlinear steering drive with a digital microcontroller by S. V. Gryzin

“…The algorithms are essentially nonlinear in nature and are based on a change in the gain of the direct circuit of the drive depending on the frequency of the input signal, which greatly complicates the calculation of the transfer function of the steering drive for use in the frequency model of the stabilization system. …”
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Improving frequency stability in grid-forming inverters with adaptive model predictive control and novel COA-jDE optimized reinforcement learning by Muhammad Zubair Yameen, Zhigang Lu, Fayez F. M. El-Sousy, Waqar Younis, Baqar Ali Zardari, Abdul Khalique Junejo

“…This process, termed cost function minimization using COA-jDE in a reinforcement learning framework, enhances GFM performance by adaptively adjusting virtual inertia and damping. …”
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Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. by Dylan Carter-Cusack, Stephen Huang, Sahar Keshvari, Omkar Patkar, Anuj Sehgal, Rachel Allavena, Robert A J Byrne, B Paul Morgan, Stephen J Bush, Kim M Summers, Katharine M Irvine, David A Hume

“…To dissect the phenotype and function of macrophages in postnatal development, we generated transcriptomic profiles of all major organs of wild-type and Csf1rko rats at weaning and in selected organs following rescue by BMT. …”
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Responses of Tomato Photosystem II Photochemistry to Pegylated Zinc-Doped Ferrite Nanoparticles by Ilektra Sperdouli, Kleoniki Giannousi, Julietta Moustaka, Orestis Antonoglou, Catherine Dendrinou-Samara, Michael Moustakas

“…An inhibitory effect on PSII function was observed after more than ~120 min exposure to both ZnFer NPs concentrations, implying a negative effect on PSII photochemistry. …”
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Role of metabolic transformation in cancer immunotherapy resistance: molecular mechanisms and therapeutic implications by Sandesh Shende, Jaishriram Rathored, Tanushree Budhbaware

“…Myeloid-derived suppressor cells and regulatory T cells are promoted, immune responses are suppressed, and T cell activity is impaired when lactate and other metabolites build up. changes in the metabolism of amino acids in the pathways for arginine and tryptophan, which are nutrients crucial for immune function. By enhancing their function in the tumour microenvironment, these metabolic alterations aid in resistance to immune checkpoint inhibitors. …”
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Continuous tunability of refractive index contrast in LiNbO3 optical waveguides fabricated by high-vacuum vapor-phase proton exchange by Mihnea Raoul Sandu, Alicia Petronela Rambu, Laura Hrostea, Sorin Tascu

“…Additionally, the index contrast dependence of the annealing time is also fitted by an exponential function. …”
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Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke by Solmaz Najjary, Hossein Mostafavi, Hadi Feizi, Fatemeh Moradi, Mehdi Eskandari

“…Pretreatment with cinnamon significantly diminished the P-Selectin protein levels as compared with the model group dose dependently (p<0.001).Conclusion: It seems that cinnamon restores BBB function by regulating the elements involved in its permeability.…”
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Influence of the course of type 1 diabetes on the left ventricular myocardial geometry and intracardiac hemodynamic. by K. I. Moshenets

“…The aim of the study was to examine changes in left ventricle (LV) geometry and to evaluate the systolic and diastolic function of LV in patients with type 1 diabetes mellitus (T1DM) depending on the course of the disease. …”
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Space as a Semantic Unit of a Language Consciousness by Віталій Шимко, Анжела Бабаджанова

“…The indicated correlation performs the function of space identification in terms of recognizing its properties and their subjective significance, depending on the features of the observer`s motivational sphere. …”
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Baxdrostat and finerenone: new aldosterone synthase-aldosterone-mineralocorticoid receptor hormonal system inhibitors for the drug treatment of resistant arterial hypertension by O. B. Kuzmin, N. V. Buchneva, V. V. Belyanin, V. V. Zhezha, M. V. Stolbova

“…Its assumed that in this pathological process, in addition to aldosterone, is also involved the small Rho GTFase Rac1 — regulatory G-protein, which can enter into a direct ligand-independent interaction with mineralcorticoid receptors, performing the function of a powerful nonsteroidal activator of the transmission of their intracellular signals. …”
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Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations. by Kevin C Knower, Sabine Kelly, Louisa M Ludbrook, Stefan Bagheri-Fam, Helena Sim, Pascal Bernard, Ryohei Sekido, Robin Lovell-Badge, Vincent R Harley

“…<h4>Background</h4>In human embryogenesis, loss of SRY (sex determining region on Y), SOX9 (SRY-related HMG box 9) or SF1 (steroidogenic factor 1) function causes disorders of sex development (DSD). …”
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In vivo antidiabetic and ex-vivo antioxidant activities of dichloromethane extract of Xerophyta spekei by Michael Musila Ndile, Wycliffe Arika Makori, Cromwell Mwiti Kibiti, Mathew Piero Ngugi

“…After 21 days, lipid profiles, kidney and liver function tests as well as ex vivo antioxidant assays were carried out. …”
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