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7861
The effect of changes in the economic performance of the region on the level of road transport
Published 2017-08-01“…The analysis of the changes in transportation volumes and freight turnover by year in the Russian Federation and in the Krasnodar region have been identified and formalized their functional dependence. Knowing the value of the equation of the trend for a specific region, with a high degree of approximation, and make predictions.…”
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7862
Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription
Published 2025-02-01“…RBPJ could bind to the MCM4 promoter to suppress the luciferase activity. Further functional analysis revealed that the functions of KAT2B in UCEC cell proliferation, DNA damage and apoptosis were mediated by MCM4, and Celastrol enhanced RBPJ acetylation and reduced MCM4 expression. …”
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7863
SAR evaluation of MIMO antennas with a wide tunable range power divider
Published 2025-04-01“…It is found that over a wide tunable power ratio range from 0.1 to 10, the local average MIMO-SAR is dependent on weight function combinations. When the human body is very close to the antenna, the coupling between the microstrip structure of the PD and the human body will affect the local average SAR. …”
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7864
Prenatal Hyperhomocysteinemia Leads to Synaptic Dysfunction and Structural Alterations in the CA1 Hippocampus of Rats
Published 2025-02-01“…Prenatal hyperhomocysteinemia (HCY) is associated with neurodevelopmental deficits, yet its long-term impact on hippocampal synaptic function remains poorly understood. This study examines the effects of moderate maternal HCY on excitatory synaptic transmission in the CA1 region of the dorsal hippocampus in rat offspring at juvenile (P21) and adult (P90) stages. …”
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7865
Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7...
Published 2025-06-01“…In cancer cells, a decrease in CI activity by RNA interference (RNAi) against NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1) arrested the cell cycle at the G1/S phase, accompanying upregulation of p21Cip1 cyclin‐dependent kinase inhibitor expression. Mechanistically, a decrease in the NAD+/NADH ratio downregulated SIRT3 and SIRT7 function, which suppressed p21Cip1 expression at the translational and transcriptional levels, respectively, resulting in the upregulation of the antiproliferative molecule. …”
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7866
Metformin Inhibits the Expression of Biomarkers of Fibrosis of EPCs In Vitro
Published 2019-01-01“…Endothelial progenitor cells (EPCs) are a group of circulating cells with important functions in vascular repair and treatment of cardiovascular diseases. …”
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7867
Inverse unit compound Rayleigh distribution: statistical properties with applications in different fields
Published 2025-08-01“…The graph of the hazard rate function of the IUCRD is the upside-down bathtub shape or nondecreasing. …”
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7868
A minimized symbiotic gene set from the 1.68 Mb pSymB chromid of Sinorhizobium meliloti reveals auxiliary symbiotic loci
Published 2025-07-01“…By employing a strain in which pSymB was removed, we used a gain-of-function approach to assess a select group of known symbiotic regions totalling 261 kb (15.5%) of pSymB. …”
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7869
Myoglobin regulates fatty acid trafficking and lipid metabolism in mammary epithelial cells.
Published 2022-01-01“…We conclude that MB can function in mammary epithelia as intracellular O2-dependent shuttle of oxidizable fatty acid substrates. …”
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7870
Modeling the Truck Appointment System as a Multi-Player Game
Published 2022-07-01“…Moreover, the solution of the multi-player model is not dependent on the objective function coefficients, unlike the single player model. …”
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7871
Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions.
Published 2010-08-01“…Our data show that T6SSs within a single organism can have distinct functions in eukaryotic versus bacterial cell interactions. …”
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7872
Center Impedance Method for Estimating Complex Modulus with Wide Frequency Range and Large Loss Factors
Published 2021-01-01“…A simple method for determining viscoelasticity over a wide frequency range using the frequency response function (FRF) mobility obtained by the center impedance method is presented. …”
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7873
A New Era of Muscarinic Acetylcholine Receptor Modulators in Neurological Diseases, Cancer and Drug Abuse
Published 2025-03-01“…The cholinergic pathways in the central nervous system (CNS) play a pivotal role in different cognitive functions of the brain, such as memory and learning. …”
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7874
Research progress on cuproptosis and copper related anti-tumor therapy
Published 2025-04-01“…Abstract Copper is a trace element which is essential for biological organisms, and its homeostatic balance is important for living organisms to maintain the normal function. When the copper homeostasis is disordered, the cellular function and structure will be disrupted. …”
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7875
Existence and Nonexistence of Positive Solutions for Fractional Boundary Value Problems with Lidstone-Inspired Fractional Conditions
Published 2025-04-01“…Our method involves constructing Green’s function by convolving the Green functions of a lower-order fractional boundary value problem and a conjugate boundary value problem and using properties of this Green function to apply the Guo–Krasnosel’skii fixed-point theorem. …”
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7876
The effect of acute exercise on cognition
Published 2020-12-01“…We demonstrate improvement in cognitive function depending on hippocampus (short-term memory) and prefrontal cortex (attention, cognitive flexibility). …”
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7877
METHOD OF IDENTIFICATION OF OBJECT STATES ACCORDING TO THE RESULTS OF FUZZY MEASUREMENTS OF CONTROLLED PARAMETERS
Published 2021-12-01“…For each of these states, the function of belonging to the fuzzy values of the corresponding parameter is defined. …”
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7878
Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro µ-opioid receptor assays and in vivo behavioral studies in mice
Published 2024-12-01“…The results showed that all nitazenes bound to MOR with nanomolar affinities, and the functional potency of several of them was comparable to or exceeded that of fentanyl. …”
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7879
Multi-channel spatio-temporal graph attention contrastive network for brain disease diagnosis
Published 2025-02-01“…Specifically, we first construct dynamic brain functional networks from fMRI data with sliding windows, and embed the structural connectivity derived from diffusion tensor imaging (DTI) to the dynamic functional connectivity graph representation to construct multi-modal brain network. …”
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7880
Latest advance anti-inflammatory hydrogel wound dressings and traditional Lignosus rhinoceros used for wound healing agents
Published 2024-11-01“…We summarized the development of functional hydrogel dressings and traditional Lignosus rhinoceros used for wound healing agents in recent years, as well as the current situation and future trends, in light of their preparation mechanisms and functional effects.…”
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