The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling by Naoyuki Kondo, Yuko Mimori-Kiyosue, Keizo Tokuhiro, Giuseppe Pezzotti, Tatsuo Kinashi

“…These findings uncover a function of LC3 and expand our understanding of lymphocyte regulation via LFA1.…”
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Cell surface receptors for signal transduction and ligand transport: a design principles study. by Harish Shankaran, Haluk Resat, H Steven Wiley

“…Our analysis reveals that the location of a receptor system in the avidity-consumption parameter space can be used to understand both its function and its regulation.…”
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MicroRNA-133 inhibits behavioral aggregation by controlling dopamine synthesis in locusts. by Meiling Yang, Yuanyuan Wei, Feng Jiang, Yanli Wang, Xiaojiao Guo, Jing He, Le Kang

“…Genes involved in dopamine synthesis have been shown to regulate the phase transition of locusts. However, the function of microRNAs in this process remains unknown. …”
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Bilateral Wilms Tumour: Is Neoadjuvant Doxorubicin Necessary? by Tristan Boam, Sri Paran, Israel Fernández-Pineda

“…Chemotherapy includes the use of vincristine and actinomycin-D in both protocols, but the COG approach also includes the use of doxorubicin, which is a cardiotoxic drug with important long-term effects on the cardiac function of childhood cancer survivors. What doxorubicin adds to patients with BWT in terms of radiological tumour response, resectability, long-term renal function and overall survival, is still not very well described and it may be variable depending on the tumour biology. …”
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The loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome. by Il-Young Hwang, Chung Park, Thuyvi Luong, Kathleen A Harrison, Lutz Birnbaumer, John H Kehrl

“…The organization of these compartments depends upon signaling initiated by G-protein linked chemoattractant receptors. …”
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The Physical Discourse of Fan Fiction by Hodunok Zoriana

“…But woman’s eyes and hands realize her emotions and feelings. It depends on stereotypical gender roles of mass culture: man has a function to interact with the world, and woman has a function to safe life inside (to give birth), which is confirmed by the free associative experiment. …”
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Sensitivity Analysis of Effective Parameters in Borehole Failure, Using Neural Network by Somaie Jolfaei, Ali Lakirouhani

“…According to the results, increasing the failure function of the area around the breakout tip causes the breakout to expand, until the failure function is less than 1 for all points around the breakout tip, at which point the breakout expansion is stopped and breakout reaches stability. …”
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THE SOLUTION TO THE EQUATION OF THE SHOCK WAVE BURGERS IN THE PTC MATHCAD ENVIRONMENT by R. E. Oleynikova

“…However, this error is detected through the values of the nonlinear term included in the differential equation, which is determined according to the binomial representation through the quadratic forms of the matrix of the trial function. These trends allow us to obtain an approximate solution from a limited number of members of the trial 92 function sufficient for accurate simulation of the solution in a wide range of Reynolds numbers characterizing the ratio of nonlinear and dissipative terms in the Navier - Stokes equation. …”
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Human Action Recognition Based on The Skeletal Pairwise Dissimilarity by E.E. Surkov, O.S. Seredin, A.V. Kopylov

“…The article presents the human figure representing approach based on pairwise dissimilarity function of skeletal models and a set of reference objects, also known as a basic assembly. …”
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ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila. by Emiliana Tognon, Nadine Wollscheid, Katia Cortese, Carlo Tacchetti, Thomas Vaccari

“…Drosophila genes encoding ESCRT-I, -II, -III components function in sorting signaling receptors, including Notch and the JAK/STAT signaling receptor Domeless. …”
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SCHEDULING PROBLEMS OF STATIONARY OBJECTS WITH THE PROCESSOR IN ONE-DIMENSIONAL ZONE by N. A. Dunichkina, D. I. Kogan, Yu. S. Fedosenko

“…The individual penalty function is assigned to every object, the function depending on the servicing completion time. …”
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Deep Thermalization under Charge-Conserving Quantum Dynamics by Rui-An Chang, Harshank Shrotriya, Wen Wei Ho, Matteo Ippoliti

“…“Deep thermalization” describes the emergence of universal wave-function distributions in quantum many-body dynamics, appearing on a local subsystem upon measurement of its environment. …”
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Structural Evaluation of the Effect of Bone Quality on the Mechanical Interaction between Dental Implants and Bone by Nazanin Karami, Mehdi Razeghi

“…The role determinant in the success of implant therapy is the function of the geometry and mechanical properties of the implant, jaw and bone-implant joint. …”
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Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review) by M. D. Salimova, Ya. G. Nadelyaeva, I. N. Danusevich

“…POI, defined as amenorrhea due to the loss of ovarian function before 40 years of age, can occur spontaneously or be secondary to medical therapies. …”
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In Search of Novel Targets for Heart Disease: Myocardin and Myocardin-Related Transcriptional Cofactors by Alexander T. Mikhailov, Mario Torrado

“…A close examination of the findings identifies the MYOCD-related transcriptional cofactors as putative therapeutic targets to improve cardiac function in heart failure conditions through distinct context-dependent mechanisms. …”
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Considerations in Orbital Reconstruction for the Oncologic Surgeon: Critical versus Optimal Objectives by Alex T. Legocki, Brett A. Miles

“…Background Orbital reconstruction following oncologic midface resection is uniquely challenging, and makes critical contributions to patient aesthetics, function, and identity. Approach is largely dependent on surgeon and patient preferences, and there exists no consensus on defect characterization. …”
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Optimization of Ultrasonic Extraction of Total Flavonoids from Cinnamonum zeylaniccum by Seyma Balcı, Sibel Yiğitarslan

“…Design-Expert software was used to obtain the function representing the extraction yield surface depending on the selected parameters. …”
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Efficacy of high-frequency rTMS for cognitive impairment in multiple sclerosis: a comparative study of RRMS and SPMS by Esraa Hasan Ebrahim Elsesy, Rasha El Bialy El Sharkawy, Marwa Abdellah Osman

“…Conclusion These findings suggest that high-frequency rTMS may be a beneficial therapeutic option for improving cognitive function in both RRMS and SPMS patients. However, the degree of cognitive enhancement may vary depending on the disease course.…”
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The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice. by Lee Smith, John Willan, Nick Warr, Frances A Brook, Michael Cheeseman, Richard Sharpe, Pam Siggers, Andy Greenfield

“…In order to address its physiological function, we have generated mice lacking Maestro using gene targeting. …”
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Mdga2 deficiency leads to an aberrant activation of BDNF/TrkB signaling that underlies autism-relevant synaptic and behavioral changes in mice. by Dongdong Zhao, Yuanhui Huo, Naizhen Zheng, Xiang Zhu, Dingting Yang, Yunqiang Zhou, Shengya Wang, Yiru Jiang, Yili Wu, Yun-Wu Zhang

“…These results highlight a novel MDGA2-BDNF/TrkB-dependent mechanism underlying the synaptic function regulation, which may become a therapeutic target for ASD.…”
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